scholarly journals Surgical Management of Multiple Myeloma and Plasmocytoma of the Spine

2020 ◽  
pp. 054-059
Author(s):  
Evangelisti G ◽  
Pesce E ◽  
Gala R ◽  
Bandiera S ◽  
Tedesco G ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Surgical Management

scholarly journals Successfully non-surgical management of flail chest as first manifestation of multiple myeloma: A case report

2019 ◽  
Vol 8 (5) ◽  
pp. 59-63
Author(s):  
Rosana Muñoz-Bermúdez ◽  
Eugenia Abella ◽  
Flavio Zuccarino ◽  
Joan Ramon Masclans ◽  
Juan Nolla-Salas
Keyword(s):  
Multiple Myeloma ◽  
Case Report ◽  
Surgical Management ◽  
Flail Chest

scholarly journals Surgical Management of Multiple Myeloma With Symptomatic Involvement of the Spine

10.14444/7112 ◽  
2020 ◽  
Vol 14 (5) ◽  
pp. 785-794
Author(s):  
HELENA MILAVEC ◽  
NIVETHA RAVIKUMAR ◽  
NICHOLAS L. SYN ◽  
CINNIE YENTIA SOEKOJO ◽  
WEE JOO CHNG ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Surgical Management

scholarly journals Successfully non-surgical management of flail chest as first manifestation of multiple myeloma: A case report

2019 ◽  
Vol 8 (5) ◽  
pp. 59-63 ◽  
Author(s):  
Rosana Muñoz-Bermúdez ◽  
Eugenia Abella ◽  
Flavio Zuccarino ◽  
Joan Ramon Masclans ◽  
Juan Nolla-Salas
Keyword(s):  
Multiple Myeloma ◽  
Case Report ◽  
Surgical Management ◽  
Flail Chest

scholarly journals Successfully non-surgical management of flail chest as first manifestation of multiple myeloma: A case report

2019 ◽  
Vol 8 (5) ◽  
pp. 82-86
Author(s):  
Rosana Muñoz-Bermúdez ◽  
Eugenia Abella ◽  
Flavio Zuccarino ◽  
Joan Ramon Masclans ◽  
Juan Nolla-Salas
Keyword(s):  
Multiple Myeloma ◽  
Case Report ◽  
Surgical Management ◽  
Flail Chest

The surgical management of abdominal pain in the multiple myeloma patient

2012 ◽  
Vol 203 (2) ◽  
pp. 127-131 ◽  
Author(s):  
Jared Garrett ◽  
V. Suzanne Klimberg ◽  
Elias Anaissie ◽  
Bart Barlogie ◽  
Richard Turnage ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Abdominal Pain ◽  
Surgical Management ◽  
Myeloma Patient ◽  
Multiple Myeloma Patient

Proteasome inhibitors as therapeutics

2005 ◽  
Vol 41 ◽  
pp. 205-218
Author(s):  
Constantine S. Mitsiades ◽  
Nicholas Mitsiades ◽  
Teru Hideshima ◽  
Paul G. Richardson ◽  
Kenneth C. Anderson
Keyword(s):  
Multiple Myeloma ◽  
Drug Class ◽  
Proteasome Inhibitors ◽  
Cell Cycle Regulators ◽  
Current State ◽  
Intracellular Mechanism ◽  
Ubiquitin Proteasome ◽  
Proteasome Pathway ◽  
Hodgkin's Lymphomas ◽  
Clinical Research Data

The ubiquitin–proteasome pathway is a principle intracellular mechanism for controlled protein degradation and has recently emerged as an attractive target for anticancer therapies, because of the pleiotropic cell-cycle regulators and modulators of apoptosis that are controlled by proteasome function. In this chapter, we review the current state of the field of proteasome inhibitors and their prototypic member, bortezomib, which was recently approved by the U.S. Food and Drug Administration for the treatment of advanced multiple myeloma. Particular emphasis is placed on the pre-clinical research data that became the basis for eventual clinical applications of proteasome inhibitors, an overview of the clinical development of this exciting drug class in multiple myeloma, and a appraisal of possible uses in other haematological malignancies, such non-Hodgkin's lymphomas.

Surgical Management of Patients With 22q11.2 Deletion Syndrome

2019 ◽  
Vol 4 (5) ◽  
pp. 857-869
Author(s):  
Oksana A. Jackson ◽  
Alison E. Kaye
Keyword(s):  
Surgical Management ◽  
Preoperative Evaluation ◽  
Preoperative Assessment ◽  
22Q11.2 Deletion Syndrome ◽  
Deletion Syndrome ◽  
22Q11.2 Deletion ◽  
Surgical Decision ◽  
Obstructive Sleep ◽  
Spine Abnormalities ◽  
Speech Assessment

Purpose The purpose of this tutorial was to describe the surgical management of palate-related abnormalities associated with 22q11.2 deletion syndrome. Craniofacial differences in 22q11.2 deletion syndrome may include overt or occult clefting of the palate and/or lip along with oropharyngeal variances that may lead to velopharyngeal dysfunction. This chapter will describe these circumstances, including incidence, diagnosis, and indications for surgical intervention. Speech assessment and imaging of the velopharyngeal system will be discussed as it relates to preoperative evaluation and surgical decision making. Important for patients with 22q11.2 deletion syndrome is appropriate preoperative screening to assess for internal carotid artery positioning, cervical spine abnormalities, and obstructive sleep apnea. Timing of surgery as well as different techniques, common complications, and outcomes will also be discussed. Conclusion Management of velopharyngeal dysfunction in patients with 22q11.2 deletion syndrome is challenging and requires thoughtful preoperative assessment and planning as well as a careful surgical technique.

Bone sialoprotein mRNA and protein expression in human multiple myeloma cell lines and patients

2000 ◽  
Vol 111 (4) ◽  
pp. 1118-1121 ◽  
Author(s):  
A. Bellahcene ◽  
I. Van Riet ◽  
C. de Greef ◽  
N. Antoine ◽  
M. F. Young ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Protein Expression ◽  
Cell Lines ◽  
Myeloma Cell ◽  
Bone Sialoprotein ◽  
Multiple Myeloma Cell ◽  
Human Multiple Myeloma ◽  
Mrna And Protein Expression
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