scholarly journals Influence of TiO2 on Mucosal Permeation of Aceclofenac: Analysis of Crystal Strain and Dislocation Density

2020 ◽  
Vol 67 (4) ◽  
pp. 1227-1232
Author(s):  
Souvik Nandi ◽  
Satyaki Aparajit Mishra ◽  
Rudra Narayan Sahoo ◽  
Rakesh Swain ◽  
Subrata Mallick

Titanium dioxide can adhere with human epithelial cells and have good tolerability. Present work has been undertaken to explore the influence of TiO2 on mucosal permeation of aceclofenac. Mucosal permeation of aeclofenac solution containing TiO2 has been carried out. In fourier transform infrared spectrosopy (FTIR), the intensity of the peaks has decreased along with the increase of TiO2 content in the formulation indicating a possible binding between drug and TiO2. Melting enthalpy has been decreased with the increased content of TiO2 in the solid. The status of crystal strain and dislocation density of TiO2 and aceclofenac in the solid state formulation has also been evaluated from Xray Diffraction data using Debye-Scherrer’s equation. Mucosal permeation of aceclofenac has shown sustained effect for more than 20 h in presence of titanium dioxide. Titanium dioxide could be used in designing formulation for sustaining mucosal aceclofenac delivery after performing risk assessment study.

2019 ◽  
Vol 70 (8) ◽  
pp. 2747-2752
Author(s):  
Constantin Marutoiu ◽  
Ioan Bratu ◽  
Mircea Gelu Buta ◽  
Olivia Florena Nemes ◽  
Sergiu Petru Timbus(Monk Siluan) ◽  
...  

A two-sided wooden icon from a monastery in Transylvania was submitted for multidisciplinary investigations involving X-Ray Fluorescence, Radiographic Photographyand Fourier Transform Infrared Spectroscopy. The most important part of the icon is St. Nicholas wooden icon, painted over forty years ago. The spectroscopic methods used revealed the painting materials composition, the status of the wooden stage, and the presence of resins as varnish (Fourier Transform Infrared Spectroscopy). On one side, the St Nicholasicon was painted over an old icon, St. Arch. Michael, which was evidenced by X-Ray Photography. The obtained data can serve for the preservation and the restoration of these wooden icons.


2021 ◽  
Author(s):  
Somayeh Kheirati Rounizi ◽  
Fateme Akrami Mohajeri ◽  
Hamdollah Moshtaghi Broujeni ◽  
Fatemeh Pourramezani ◽  
Sara Jambarsang ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 1850-1861
Author(s):  
Aarzoo ◽  
Saba Naqvi ◽  
Nidhi Bharal Agarwal ◽  
Manoj P. Singh ◽  
M. Samim

The surge in vehicular activity in densely populated areas has led to an increased concentration of airborne palladium nanoparticles (PdNPs) in the environment.


2008 ◽  
Vol 59 (2) ◽  
pp. 147-152 ◽  
Author(s):  
E. Fuller Torrey ◽  
Jonathan Stanley ◽  
John Monahan ◽  
Henry J. Steadman

Author(s):  
Soimita Suciu ◽  
Dana Dabala ◽  
Adrian Florea ◽  
Alexandra Sevastre-Berghian ◽  
Emanoil Surducan ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document