The Difference of Verbal Fluency Task Performance between Alzheimer’s Disease and Subcortical Vascular Dementia: CREDOS (Clinical Research Center for Dementia of South Korea) Study

2016 ◽  
Vol 34 (1) ◽  
pp. 14-22
Author(s):  
Yisuh Ahn ◽  
Jong Hun Kim ◽  
Seong Hye Choi ◽  
Jee Hyang Jeong ◽  
Bon D. Ku ◽  
...  
Keyword(s):  
South Korea ◽  
Clinical Research ◽  
Vascular Dementia ◽  
Task Performance ◽  
Verbal Fluency ◽  
Verbal Fluency Task ◽  
Subcortical Vascular Dementia ◽  
Clinical Research Center ◽  
The Difference ◽  
Fluency Task

scholarly journals Semantic, phonologic, and verb fluency in Huntington's disease

2007 ◽  
Vol 1 (4) ◽  
pp. 381-385 ◽  
Author(s):  
Mariana Jardim Azambuja ◽  
Monica Santoro Haddad ◽  
Marcia Radanovic ◽  
Egberto Reis Barbosa ◽  
Letícia Lessa Mansur
Keyword(s):  
Executive Functioning ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Task Performance ◽  
Verbal Fluency ◽  
Frontal Lobe Dysfunction ◽  
Semantic Fluency ◽  
Verbal Fluency Task ◽  
Usual Evaluation ◽  
Fluency Task

Abstract Verbal fluency tasks have been identified as important indicators of executive functioning impairment in patients with frontal lobe dysfunction. Although the usual evaluation of this ability considers phonologic and semantic criteria, there is some evidence that fluency of verbs would be more sensitive in disclosing frontostriatal physiopathology since frontal regions primarily mediate retrieval of verbs. Huntington's disease usually affects these circuitries. Objective: To compare three types of verbal fluency task in the assessment of frontal-striatal dysfunction in HD subjects. Methods: We studied 26 Huntington's disease subjects, divided into two subgroups: mild (11) and moderate (15) along with 26 normal volunteers matched for age, gender and schooling, for three types of verbal fluency: phonologic fluency (F-A-S), semantic fluency and fluency of verbs. Results: Huntington's disease subjects showed a significant reduction in the number of words correctly generated in the three tasks when compared to the normal group. Both controls and Huntington's disease subjects showed a similar pattern of decreasing task performance with the greatest number of words being generated by semantic elicitation followed by verbs and lastly phonologic criteria. We did not find greater production of verbs compared with F-A-S and semantic conditions. Moreover, the fluency of verbs distinguished only the moderate group from controls. Conclusion: Our results indicated that phonologic and semantic fluency can be used to evaluate executive functioning, proving more sensitive than verb fluency. However, it is important to point out that the diverse presentations of Huntington's disease means that an extended sample is necessary for more consistent analysis of this issue.

scholarly journals Fully Automatic Speech-Based Analysis of the Semantic Verbal Fluency Task

2018 ◽  
Vol 45 (3-4) ◽  
pp. 198-209 ◽  
Author(s):  
Alexandra König ◽  
Nicklas Linz ◽  
Johannes Tröger ◽  
Maria Wolters ◽  
Jan Alexandersson ◽  
...  
Keyword(s):  
Task Performance ◽  
Verbal Fluency ◽  
Area Under Curve ◽  
Semantic Category ◽  
Verbal Fluency Task ◽  
Semantic Verbal Fluency ◽  
Fine Grained ◽  
Fully Automatic ◽  
Highly Correlated ◽  
Fluency Task

Background: Semantic verbal fluency (SVF) tests are routinely used in screening for mild cognitive impairment (MCI). In this task, participants name as many items as possible of a semantic category under a time constraint. Clinicians measure task performance manually by summing the number of correct words and errors. More fine-grained variables add valuable information to clinical assessment, but are time-consuming. Therefore, the aim of this study is to investigate whether automatic analysis of the SVF could provide these as accurate as manual and thus, support qualitative screening of neurocognitive impairment. Methods: SVF data were collected from 95 older people with MCI (n = 47), Alzheimer’s or related dementias (ADRD; n = 24), and healthy controls (HC; n = 24). All data were annotated manually and automatically with clusters and switches. The obtained metrics were validated using a classifier to distinguish HC, MCI, and ADRD. Results: Automatically extracted clusters and switches were highly correlated (r = 0.9) with manually established values, and performed as well on the classification task separating HC from persons with ADRD (area under curve [AUC] = 0.939) and MCI (AUC = 0.758). Conclusion: The results show that it is possible to automate fine-grained analyses of SVF data for the assessment of cognitive decline.

scholarly journals Detection of prefrontal lobe blood flow changes in patients with obsessive-compulsive disorder during a verbal fluency task by near-infrared reflectance spectroscopy

2020 ◽  
Vol 61 (2) ◽  
pp. 132-141
Author(s):  
Yin Hong-Ying ◽  
Fan Jiang ◽  
Qi-Hua Peng ◽  
Yu-Ling Wu
Keyword(s):  
Verbal Fluency ◽  
Near Infrared ◽  
Spectral Characteristics ◽  
Obsessive Compulsive ◽  
Near Infrared Reflectance ◽  
Verbal Fluency Task ◽  
Compulsive Disorder ◽  
Compulsive Behaviors ◽  
The Difference ◽  
Fluency Task

The purpose of this work was to use near-infrared reflectance spectroscopy (NIRS) to investigate the spectral characteristics and frontal lobe activation in patients with obsessive-compulsive disorder (OCD) during a verbal fluency task. Thirty-seven patients with OCD, who met the diagnostic criteria of International Classification of Diseases 10 (ICD-10), were recruited. The total score of the Symptom Checklist (SCL-90, grade 1-5) was ≥160 points. The total score of the Yale-Brown Obsessive Compulsive Scale was ≥7 points. The changes in frontal lobe blood flow were measured by NIRS when completing a verbal fluency task. Then, the differences between obsessive-compulsive thoughts and obsessive-compulsive behaviors in OCD, and the concentration variation of oxygenate hemoglobin (Oxy-Hb) and deoxygenate hemoglobin (Deoxy-Hb) were investigated. The difference was significant (P<0.03) between obsessive-compulsive behaviors and obsessive-compulsive thoughts. Obsessive-compulsive behaviors were positively correlated (P<0.01, P<0.05) with depression, anxiety, psychosis and other factors in the SCL-90, and significantly positively correlated (P<0.01, P<0.03) with somatization, hostility and paranoid factor scores in the SCL-90. There was also a trend of partial overlap between the waveform and task period, and the difference was significant (P<0.01) between these. Obsessive-compulsive thoughts were negatively correlated (P<0.05) with channels 9 and 19. The NIRS monitoring spectrum for patients with OCD has certain spectral characteristics of schizophrenia, but there is a repetitive trend between the recovery period and the task period.

scholarly journals Activation of the hypothalamic-pituitary adrenal axis in response to a verbal fluency task and associations with task performance

2019 ◽  
Author(s):  
Linda Becker ◽  
Ursula Schade ◽  
Nicolas Rohleder
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Task Performance ◽  
Hpa Axis ◽  
Verbal Fluency ◽  
Field Studies ◽  
Hypothalamic Pituitary Adrenal ◽  
Verbal Fluency Task ◽  
Acute Stressor ◽  
Fluency Task

AbstractSpeech fluency can be impaired in stressful situations. The aim of the present study was to investigate whether a verbal fluency task without any further stress induction by itself induces responses of the hypothalamic-pituitary adrenal (HPA) axis and of the sympathetic nervous system (SNS).The sample consisted of n = 85 participants (68.2% female; 33.3 ± 15.2 years, BMI = 23.7 ± 4.3 kg/m2) who performed two consecutive verbal fluency tasks for two minutes each. The categories were either ‘stress’ or ‘disease’ and ‘animals’ or ‘foods’ which were presented in a randomized order. Three saliva samples were collected, prior to the task (t0), immediately after (t1), and ten minutes after (t2). Salivary α-amylase and cortisol were assessed. Furthermore, blood pressure, heart rate, and subjective ratings of actual stress perception, level of effort, and tiredness were measured.The verbal fluency task induced an HPA axis response with a maximum cortisol level at t2 (p < .001, ηp2 = .19) which was independent of task performance. Furthermore, subjective stress and effort as well of tiredness increased immediately after the task (all p < .001; all d ≥ 1.0). Tiredness immediately after the task was negatively correlated with task performance (p = .002). No α-amylase, blood pressure or heart rate responses were found.We conclude that a verbal fluency task acts like an acute stressor that induces a cortisol response without the need of further (e.g., social-evaluative) stress components. Therefore, it is a little time-consuming alternative to other stress tasks that can be used in field studies with little effort.

scholarly journals Verbal fluency task performance in persons with moderate intellectual disability

2018 ◽  
Vol 17 (3) ◽  
pp. 283-305
Author(s):  
Milica Gligorović ◽  
Nataša Buha ◽  
Bojan Dučić ◽  
Svetlana Kaljača
Keyword(s):  
Intellectual Disability ◽  
Task Performance ◽  
Verbal Fluency ◽  
Verbal Fluency Task ◽  
Moderate Intellectual Disability ◽  
Fluency Task

scholarly journals EXPRESS: Attention in Post-Lexical Processes of Utterance Production: Dual-Task Cost in Younger and Older Adults

2021 ◽  
pp. 174702182110341
Author(s):  
Maryll Fournet ◽  
Michaela Pernon ◽  
Sabina Catalano Chiuvé ◽  
Ursula Lopez ◽  
Marina Laganaro
Keyword(s):  
Older Adults ◽  
Dual Task ◽  
Verbal Fluency ◽  
Verbal Task ◽  
Lexical Selection ◽  
Speech Task ◽  
Verbal Fluency Task ◽  
Dual Task Cost ◽  
Lexical Processes ◽  
Fluency Task

There is a general agreement that speaking requires attention at least for conceptual and lexical processes of utterance production. However, conflicting results have been obtained with dual-task paradigms using either repetition tasks or more generally tasks involving limited loading of lexical selection. This study aimed to investigate whether post-lexical processes recruit attentional resources. We used a new dual-task paradigm in a set of experiments where a continuous verbal production task involved either high or low demand on lexical selection processes. Experiment 1 evaluates lexical and post-lexical processes with a semantic verbal fluency task, whereas experiments 2 and 3 focus on post-lexical processes with a non-propositional speech task. In each experiment, two types of non-verbal secondary tasks were used: processing speed (simple manual reaction times) or inhibition (Go/No-go). In Experiment 1, a dual-task cost was observed on the semantic verbal fluency task and each non-verbal task. In Experiment 2, a dual-task cost appeared on the non-verbal tasks but not on the speech task. The same paradigm was used with older adults (Experiment 3), as increased effort in post-lexical processes has been associated with ageing. For older adults, a dual-task cost was also observed on the non-propositional verbal task when speech was produced with the inhibition non-verbal task. The results suggest an attentional cost on post-lexical processes and strategic effects in the resolution of the dual-task.

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