scholarly journals Bladder outlet obstruction number- a good indicator of infravesical obstruction in patients with benign prostatic enlargement?

2012 ◽  
Vol 12 (3) ◽  
pp. 144
Author(s):  
Damir Aganović ◽  
Hajrudin Spahović ◽  
Alden Prcić ◽  
Osman Hadžiosmanović
Keyword(s):  
Bladder Outlet Obstruction ◽  
Outlet Obstruction ◽  
Benign Prostatic Enlargement ◽  
Infravesical Obstruction ◽  
Prostatic Enlargement

Assessment of Tamsulosin 0.2 mg for Symptomatic Bladder Outlet Obstruction Secondary to Benign Prostatic Enlargement: Data from a Korean Multicenter Cross-Sectional Study

2015 ◽  
Vol 95 (1) ◽  
pp. 50-55 ◽  
Author(s):  
Hoon Choi ◽  
Ji Sung Sim ◽  
Jae Young Park ◽  
Jae Hyun Bae
Keyword(s):  
Treatment Satisfaction ◽  
Bladder Outlet Obstruction ◽  
Outlet Obstruction ◽  
Symptomatic Improvement ◽  
Cross Sectional Study ◽  
Symptom Improvement ◽  
Benign Prostatic Enlargement ◽  
Cross Sectional ◽  
Patient Dissatisfaction ◽  
Prostatic Enlargement

Aims: To estimate efficacy and treatment satisfaction with tamsulosin 0.2 mg in patients with symptomatic bladder outlet obstruction secondary to benign prostatic enlargement and lower urinary tract symptoms in relation to personal satisfaction. Methods: The study was conducted in 1,260 subjects who were asked to fill in detailed questionnaires designed to evaluate their satisfaction with the treatment and symptom improvement 8 weeks after receiving tamsulosin 0.2 mg. Results: After being treated with tamsulosin 0.2 mg for 8 weeks, the International Prostate Symptom Score (IPSS) score improved significantly. Among the 1,260 patients, 813 (64.52%) were satisfied, while 447 (35.48%) were dissatisfied with tamsulosin 0.2 mg. The reasons for patient dissatisfaction were efficacy problems (79.87%) and side effects (4.25%). Treatment satisfaction was affected by age, underlying medical disease and baseline IPSS severity (p = 0.020, 0.0427 and <0.001, respectively), but only age and baseline IPSS were risk factors for dissatisfaction. Conclusions: Tamsulosin 0.2 mg was effective in symptomatic improvement, but a relatively high proportion of patients were dissatisfied with the treatment. Efficacy problems were selected by patients as the main reason for dissatisfaction. It is also significant to note that the degree of satisfaction was related to age and baseline IPSS severity.

scholarly journals EFEK PAPARAN GLUKOSA KONSENTRASI TINGGI TERHADAP PENINGKATKAN AKTIVITAS ISOZIM PROTEIN KINASE C (PKC)-ALPHA PADA KULTUR SEL STROMA PROSTAT

1970 ◽  
Vol 16 (1) ◽  
Author(s):  
Basuki B Purnomo ◽  
I Wayan Widharse ◽  
Aulani’am Aulani’am
Keyword(s):  
Stromal Cells ◽  
Bladder Outlet Obstruction ◽  
Primary Cultures ◽  
Outlet Obstruction ◽  
Alpha Activity ◽  
Benign Prostatic Enlargement ◽  
Kinase C ◽  
Prostatic Enlargement ◽  
Pkc Alpha ◽  
Isozyme Activity

OBJECTIVE: To prove that glucose treatment in human prostatic stromal cells (HPSC) culture would increase PKC alpha isozyme activity. MaterialS & Methods: Primary cultures of HPSC were obtained from patients with bladder outlet obstruction caused by benign prostatic enlargement. The effects of various concentrations of glucose (5, 10, 15, 20, 25, 30, 35 micro-Mol) on PKC-alpha isozyme activity were examined quantitatively by spectrophotometry methods. ResultS: Spectrophotometry analysis, which is used to assess isozyme activity quantitatively, showed that exposures to various doses of glucose resulted in increased isozyme activity. The increment of activity is linear with the increment of glucose dose. There is a strong correlation between glucose doses and PKC-alpha activity, with R2 = 0,91. Conclusion: At different concentrations glucose increases PKC-alpha isozyme activity of HPSC.

Targeting bladder outlet obstruction from benign prostatic enlargement via the nitric oxide/cGMP pathway?

2005 ◽  
Vol 96 (3) ◽  
pp. 250-253 ◽  
Author(s):  
Andre Reitz ◽  
Michael Muntener ◽  
Axel Haferkamp ◽  
Markus Hohenfellner ◽  
Brigitte Schurch
Keyword(s):  
Nitric Oxide ◽  
Bladder Outlet Obstruction ◽  
Outlet Obstruction ◽  
Benign Prostatic Enlargement ◽  
Cgmp Pathway ◽  
Prostatic Enlargement
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