scholarly journals Hepatitis C infection in risk groups

2006 ◽  
Vol 6 (4) ◽  
pp. 13-17 ◽  
Author(s):  
Sead Ahmetagić ◽  
Kasim Muminhodžić ◽  
Elmir Čičkušić ◽  
Vildana Stojić ◽  
Jasminka Petrović ◽  
...  

Hepatitis C infection is important global health problem with wide spectrum of health, social and economic consequences. The goal of this research was to estimate prevalence of hepatitis C virus infection in risk groups, and to determine association hepatitis C virus (HCV) infection and risk factors. Research included 4627 subjects divided in two groups. Test group included 2627 subjects divided in 4 subgroups with risk for HCV infection: those who received blood transfusion without screening on HCV (it was introduced in 1995) (700); intravenous drug users (60); patients on hemodialysis (168) and health care workers (1699). Control group included 2000 healthy volunteer blood donors. In all subjects anti-HCV antibodies were tested with third generation ELISA test. Positive serum samples were tested for presence of HCVRNA, using reaction of reverse transcription and polymerase chain reaction. In all anti-HCV positive subjects further epidemiological and clinical workup was performed. Prevalence of HCV infection in risk groups was: 4.6% in subjects who have received blood transfusions without HCV blood screening, 35% in intravenous drug users, 58.9% in patients on chronic dialysis, and 0.4% in health care workers. In control group prevalence was low (0.2%). In the group of 158 anti-HCV positive subjects, 73.4% had HCVRNA. The largest number of subjects with HCV infection was in the age group of 30-49 years (45.8%). This study showed that multiple blood transfusions before introducing the blood screening for HCV, longer duration of intravenous drug abuse, longer duration of hemodialysis treatment, larger number of accidental injuries in health care workers are independent and statistically significant risk factors for those groups examined. Results of this study confirm that general screening for HCV infection is recommended in risk groups for HCV infection in order to identify to prevent and to treat it.

1970 ◽  
Vol 25 (3) ◽  
pp. 126-129 ◽  
Author(s):  
Shahinul Alam ◽  
Nooruddin Ahmad ◽  
Mobin Khan ◽  
Golam Mustafa

Background and aims: Parenteral route is the principal mode of transmission of Hepatitis C Virus (HCV). Health care workers are at risk of infection with HCV. Aim of study was to estimate seroprevalence of HCV amongst health care workers and identify possible risk factors of HCV infection. Materials and Methods: 355 health care workers were selected from July 2005 to June 2006 working in different departments of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Among them 43.5% were doctors, 32.1% nurses, 11.8% ward boys, 5.9% operation theatre staffs (OT staffs), and 6.8% others. Sera were tested for HCV antibodies by ELISA. Data analyzed by SPSS 10.0 version. Results: Mean age was 31.56±7.4 years. Males were 51.4% and females 48.6%. Anti-HCV was positive in 5(1.4%) cases out of 355. Most prone to HCV infection were nurses (3) followed by doctor (2). No ward boy or OT staff was affected. Previous surgical (80%) and dental procedures (60%) were the main risk factors than recipients of blood transfusion (20%), intravenous drug users (20%), and multiple sexual exposures (20%). Conclusions: Nurses are more prone to HCV infection. Surgical procedures are the main risk factors for acquiring HCV infection. Proper sterilization of surgical instruments is recommended. (J Bangladesh Coll Phys Surg 2007; 25 : 126-129)


2021 ◽  
Vol 13 (7) ◽  
pp. 32
Author(s):  
Theresa Nwagha ◽  
Babatunde I Omotowo ◽  
Uchenna N Ijoma ◽  
Ijeoma A Meka ◽  
Obinna D Onodugo ◽  
...  

BACKGROUND: Hepatitis C virus (HCV) infection is a global public health issue. Health care workers (HCWs) are particularly at risk. Nigeria hepatitis prevention policy aims to achieve country wide elimination of hepatitis through early detection using mass screening with life-style modifications of “at risk population” which are key preventive strategies. AIM: To determine the seroprevalence of HCV infection among HCWs in a large regional referral hospital in Nigeria METHODS: A hospital-based descriptive cross-sectional study (hepatitis mass screening) was done at the University of Nigeria Teaching Hospital, Enugu, Nigeria between July and August 2016. Non-randomised sampling was used. Blood samples were assayed for antibodies to HCV. Data on knowledge, risk factors and mode of transmission were collected using a structured, pre-validated, pretested, questionnaire and analysed using SPSS version 20. RESULTS: A total of 3132 out of 5144 (60.9%) HCWs participated in the study. The seroprevalence of hepatitis C among UNTH staff was 0.90% (28/3132). The mean knowledge score of 68.95% ± 24.23 and 56.70±17.25 translates to fair knowledge level about mode of transmission and risk of transmission of hepatitis C among HCWs, respectively. There was no reported case of hepatitis B and C co-infection. Females HCWs had highest sero-prevalence for HCV 17/5144 (0.33%) (P = 0.164, AOR= 1.76, 95%CI =0.431-2.413) CONCLUSION: This study found a low seropositivity of HCV among HCWs. A pointer to the possible success of the hospital-based education awareness programme, an implementation of Nigeria’s national hepatitis prevention policy.


1995 ◽  
Vol 59 (7) ◽  
pp. 990-994 ◽  
Author(s):  
Angella M. Goetz ◽  
Oliver K. Ndimbie ◽  
Marilyn M. Wagener ◽  
Robert R. Muder

Author(s):  
B. O. M. Vanderborght ◽  
C. Rouzere ◽  
C. F. Ginuino ◽  
G. Maertens ◽  
H. Van Heuverswyn ◽  
...  

Nearly 400 hemodialysis patients treated at 5 different hemodialysis units in Rio de Janeiro were tested for one year for the presence of hepatitis C and B markers. During the same period, samples were also obtained from 35 continuous ambulatory peritoneal dialysis (CAPD) patients and from 242 health care workers. Depending on the hemodialysis unit studied, anti-HCV prevalence rates ranging from 47% to 82% (mean 65%) were detected. CAPD patients showed a lower prevalence of 17%. The prevalence of antibodies against hepatitis C virus (anti-HCV) among health care workers was 2.9%. We observed a hepatitis C attack rate of 11.5% per year in the anti-HCV-negative hemodialysis patient population. An average of 9.4% of the hemodialysis patients were chronic carriers of hepatitis B virus (HBV) (range 1.8% - 20.4%), while 48.9% showed markers of previous HBV infection. The HBV attack rate was 4.5% per year (range 0% - 6%). These results indicate an alarming high prevalence of anti-HCV among hemodialysis patients of this studied region.


2010 ◽  
Vol 38 (9) ◽  
pp. 757-758 ◽  
Author(s):  
Soehartinah Kramadibrata Antono ◽  
Reynie Purnama Raya ◽  
Sri Yusnita Irda Sari ◽  
Irvan Afriandi ◽  
Anita Deborah Anwar ◽  
...  

2020 ◽  
Vol 50 (1) ◽  
pp. 58-64
Author(s):  
Shaimaa Abdelrheem ◽  
Yosra Saleh ◽  
Hebat-Allah Abdelatif ◽  
Mohamed Elbadry

2011 ◽  
Author(s):  
Annika Parantainen ◽  
Minna Anthoni ◽  
America Valdes ◽  
Marie-Claude Lavoie ◽  
Ulla-Maija Hellgren ◽  
...  

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