scholarly journals Biosynthesis of food constituents: Vitamins. 1. Fat-soluble vitamins - a review

2008 ◽  
Vol 25 (No. 1) ◽  
pp. 1-16 ◽  
Author(s):  
J. Velíšek ◽  
K. Cejpek

This review article gives a survey of the generally accepted biosynthetic pathways that lead to fat-soluble vitamins (vitamin A, vitamin D, vitamin E, vitamin K, the corresponding provitamins, and the closely related ubiquinones and plastoquinones) in animals, plants, and microorganisms. Extensively used are reaction schemes, sequences, and mechanisms with the enzymes involved, with detailed explanations using chemical principles and mechanisms.

2020 ◽  
Vol 2 (2) ◽  
pp. 73-80
Author(s):  
Puji Lestari

Pengetahuan gizi merupakan landasan perilaku gizi seseorang, yang akan berefek pada asupan makanan dan status gizi siswi. Tujuan penelitian ialah mengetahui hubungan pengetahuan gizi dan asupan makanan dengan status gizi. Jenis penelitian adalah deskriptif dengan desain cross sectional. Subjek penelitian ini sebanyak  51 siswi Mts Darul Ulum kelas 8 dan 9. Penelitian dilakukan bulan September 2019-Februari  2020. Uji hubungan menggunakan uji  Pearson dan uji Sperman’s rho. Uji korelasi pengetahuan gizi dan asupan energi p=0,103;  protein p=0,556; lemak p= 0,570; karbohidrat p=0,261; vitamin A p=0,036; vitamin D p=0,745; vitamin E=0,506; vitamin K p=0,590; vitamin C p=0,534; natrium p=0,491; kalsium p=0,640; zat besi p= 0,323. Hasil uji korelasi asupan energi dengan status gizi p=0,021; karbohidrat p=0,107; protein p=0,020; lemak p=0,32; vitamin A p=0,242; vitamin D p=0,491; vitamin E p=0,587; vitamin K p= 0,600; vitamin C p=0,069; natrium p=0,031; kalsium p=0,077; zat besi p=0,018. Ada hubungan pengetahuan gizi dan makanan dengan status gizi.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 108-109
Author(s):  
Leandro Del Tuffo ◽  
Mike D Tokach ◽  
Cassandra K Jones ◽  
Joel M DeRouchey ◽  
Robert D Goodband

Abstract With recent increases in vitamin prices, the typical margins of safety used in formulation need to be evaluated. Therefore, the objective of this study was to compare two premixes with different vitamin concentrations on growth performance and carcass characteristics of pigs housed under commercial conditions. A total of 1,188 pigs (PIC 359×1050; initially 16.1 kg) were used in a randomized complete block design with 27 pigs per pen and 22 pens per treatment. There were two dietary treatments with different vitamin concentrations. Premix A provided the following vitamins per kg of premix: 3,527,360 IU vitamin A; 881,840 IU vitamin D, 17,637 mg vitamin E; 1,764 mg vitamin K; 15.4 mg B12; 33,069 mg niacin; 11,023 mg pantothenic acid; and 3,307 mg riboflavin. Premix B provided lower vitamin concentrations and contained the following vitamins per kg of premix: 1,653,450 IU vitamin A; 661,380 IU vitamin D; 17,637 mg vitamin E; 1,323 mg vitamin K; 13.2 mg B12; 19,841 mg niacin; 11,023 mg pantothenic acid; and 3,307 mg riboflavin. Premixes were included in the diet at 0.25, 0.15, 0.125, 0.10, and 0.075% from 16 to 27, 27 to 50, 50 to 75, 75 to 100, and 100 to 125 kg, respectively. Data were analyzed with pen as the experimental unit. Overall, there was no evidence for differences in ADG, ADFI, total pen gain and pen feed intake. There was a tendency (P = 0.089) for increased HCW for pigs fed Premix A due to a numeric increase in removal of lightweight pigs compared to pigs fed Premix B. No evidence for differences were observed for carcass traits, mortality, or percentage of pigs removed between the two treatments. In conclusion, the lower inclusions of vitamins A, D, B12, and niacin in premix B did not influence growth and carcass traits of grow-finish pigs.


Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 483
Author(s):  
Olaf Sommerburg ◽  
Susanne Hämmerling ◽  
S. Philipp Schneider ◽  
Jürgen Okun ◽  
Claus-Dieter Langhans ◽  
...  

Rationale: Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, leads to impaired pancreatic function and therefore reduced intestinal absorption of lipids and fat-soluble vitamins especially in patients with CF developing pancreatic insufficiency (PI). Previous studies showed that CFTR modulator therapy with lumacaftor-ivacaftor (LUM/IVA) in Phe508del-homozygous patients with CF results in improvement of pulmonary disease and thriving. However, the effects of LUM/IVA on plasma concentration of the lipid soluble vitamins A and E remain unknown. Objectives: To investigate the course of plasma vitamin A and E in patients with CF under LUM/IVA therapy. Methods: Data from annual follow-up examinations of patients with CF were obtained to assess clinical outcomes including pulmonary function status, body mass index (BMI), and clinical chemistry as well as fat-soluble vitamins in Phe508del-homozygous CF patients before initiation and during LUM/IVA therapy. Results: Patients with CF receiving LUM/IVA improved substantially, including improvement in pulmonary inflammation, associated with a decrease in blood immunoglobulin G (IgG) from 9.4 to 8.2 g/L after two years (p < 0.001). During the same time, plasma vitamin A increased significantly from 1.2 to 1.6 µmol/L (p < 0.05), however, levels above the upper limit of normal were not detected in any of the patients. In contrast, plasma vitamin E as vitamin E/cholesterol ratio decreased moderately over the same time from 6.2 to 5.5 µmol/L (p < 0.01). Conclusions: CFTR modulator therapy with LUM/IVA alters concentrations of vitamins A and vitamin E in plasma. The increase of vitamin A must be monitored critically to avoid hypervitaminosis A in patients with CF.


2020 ◽  
pp. 813-843
Author(s):  
Sean Ainsworth

This chapter presents information on neonatal drugs that begin with V, including use, pharmacology, adverse effects, fetal and infant implications of maternal treatment, treatment, and supply of Vancomycin, Varicella-zoster immunoglobulin and vaccine, Vasopressin, desmopressin, and terlipressin, Vigabatrin, Vitamin A (retinol), Vitamin B12 (hydroxocobalamin), Vitamin D (special formulations), Vitamin D (standard formulations), Vitamin E (alpha tocopherol), Vitamin K1 = phytomenadione (rINN), phytonadione (USAP), and Vitamins (multi-vitamins)


2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Marut Saensukjaroenphon ◽  
Caitlin E Evans ◽  
Chad B Paulk ◽  
Jordan T Gebhardt ◽  
Jason C Woodworth ◽  
...  

Abstract Feed ingredients and additives could be a potential medium for foreign animal disease entry into the United States. The feed industry has taken active steps to reduce the risk of pathogen entry through ingredients. Medium chain fatty acid (MCFA) and heat pulse treatment could be an opportunity to prevent pathogen contamination. The objective of experiment 1 was to determine the impact of 0, 30, 60, or 90 d storage time on fat-soluble vitamin stability when vitamin premix (VP) and vitamin trace mineral premix (VTM) were blended with 1% inclusion of MCFA (1:1:1 blend of C6:C8:C10) or mineral oil (MO) with different environmental conditions. Samples stored at room temperature (RT) (~22 °C) or in an environmentally controlled chamber set at 40 °C and 75% humidity, high-temperature high humidity (HTHH). The sample bags were pulled out at days 0, 30, 60 and 90 for RT condition and HTHH condition. The objective of experiment 2 was to determine the effect of heat pulse treatment and MCFA addition on fat-soluble vitamin stability with two premix types. A sample from each treatment was heated at 60 °C and 20% humidity. For experiment 1, the following effects were significant for vitamin A: premix type × storage condition (P = 0.031) and storage time × storage condition (P = 0.002) interactions; for vitamin D3: main effect of storage condition (P &lt; 0.001) and storage time (P = 0.002); and for vitamin E: storage time × storage condition interaction (P &lt; 0.001). For experiment 2, oil type did not affect the stability of fat-soluble vitamins (P &gt; 0.732) except for vitamin A (P = 0.030). There were no differences for fat-soluble vitamin stability between VP and VTM (P &gt; 0.074) except for vitamin E (P = 0.016). Therefore, the fat-soluble vitamins were stable when mixed with both vitamin and VTM and stored at 22 °C with 28.4% relative humidity (RH). When premixes were stored at 39.5 °C with 78.8%RH, the vitamin A and D3 were stable up to 30 d while the vitamin E was stable up to 60 d. In addition, MCFA did not influence fat-soluble vitamin degradation during storage up to 90 d and in the heat pulse process. The vitamin stability was decreased by 5% to 10% after the premixes was heated at 60 °C for approximately nine and a half hours. If both chemical treatment (MCFA) and heat pulse treatment have similar efficiency at neutralizing or reducing the target pathogen, the process of chemical treatment could become a more practical practice.


Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2406
Author(s):  
Yanni Papanikolaou ◽  
Victor L. Fulgoni

The purpose of the current study was to examine the cost of eggs in relation to nutrient delivery in children and adults. The present analysis used dietary intake data from the National Health and Nutrition Examination Survey 2013–2016 (egg consumers: 2–18 years-old, N = 956; 19+ years-old, N = 2424). Inflation adjusted food cost and the cost of nutrients were obtained from the Center for Nutrition Promotion and Policy food cost database. Cost and nutrient profiles for What We Eat in America food categories were compared to whole eggs. Of the 15 main food groups examined, whole eggs ranked third for lowest cost per 100 g (excluding beverages), such that eggs cost 0.35 USD per 100 g, with dairy and grains representing the first and second most cost-efficient foods, at 0.23 USD and 0.27 USD per 100 g, respectively. In children and adults, eggs represented a cost-efficient food for protein delivery, such that eggs provided nearly 2.7% and 3.7% of all protein in the diet, respectively, at a cost of about 0.03 USD per g of protein. Eggs contributed 3.8% and 6.0% of all vitamin A in the diet of children and adults, at a cost of approximately 0.002 USD and 0.003 USD per RAE mcg of vitamin A, respectively. In children 2–18 years-old, nearly 12% of all choline in the diet is delivered from eggs, at a cost of approximately 0.002 USD per mg of choline. Similarly, in adults 19-years-old+, eggs provide nearly 15% of all dietary choline in the diet, at a cost of approximately 0.002 USD per mg of choline. Eggs provide nearly 5% and 9.5% of all vitamin D in the diet of children and adults, at a cost of approximately 0.21 USD and 0.22 USD per mcg of vitamin D, respectively. Overall, eggs ranked as the most cost-efficient food for delivering protein, choline, and vitamin A, second for vitamin E, and third for vitamin D in children. In adults, eggs ranked as the most cost-efficient food for delivering protein and choline, second for vitamin A, and third for vitamin D and vitamin E. In summary, eggs represent an economical food choice for the delivery of protein and several shortfall nutrients (choline, vitamin A, and vitamin D) in the American diet.


1978 ◽  
Vol 61 (3) ◽  
pp. 735-745
Author(s):  
Ellen J De Vries ◽  
Frits J Mulder ◽  
Ben Borsje

Abstract The official first action method for determining vitamin D in multivitamin preparations was modified. The method was collaboratively studied by 7 laboratories, using 6 preparations in oil. The preparations consisted of vitamin D at various levels and at various ratios (in w/w) to vitamin A. Three samples contained cholecalciferol and 3 samples contained vitamin D3 from vitamin D3 resin. After outliers were eliminated by the Dixon test, data were analyzed and averages were compared with amounts of vitamin D known to be in each sample. For samples with vitamin D: vitamin A ratios of 1:0.5, 1:5, and 1:10, the mean vitamin D recoveries were 98.8, 94.6, and 90.7%, respectively. The method has been adopted as official final action.


2007 ◽  
Vol 77 (5) ◽  
pp. 303-310 ◽  
Author(s):  
Campos ◽  
Paixão ◽  
Ferraz

Lactation has three distinct phases: colostrum, transition, and mature, with the quantity of fat-soluble vitamins and carotenoids tending to decline while the total fat content increases. The number of deliveries seems to be directly related to higher concentrations of beta-carotene and vitamin E in colostrum. Little is known about vitamin quantities during the other phases. In the present study, vitamin A and E concentrations during different phases of lactation were measured in primiparous and multiparous mothers to analyze the variation and suitability for the diet of a breastfed child. Phase of lactation and number of deliveries were highly significant for log mean vitamin A while only one phase showed significance for log mean vitamin E. There was a sharp decline in the levels of vitamin A and E in the course of the initial phase of lactation. The variability between measurements declined as colostrum transitioned to mature milk. There were significant measurable inter-group differences in retinol levels in milk obtained during early lactation. Vitamin A and E content can reach 2.5 and 1.4 times of levels recommended intake, respectively.


2007 ◽  
Vol 17 (5) ◽  
pp. 421-432 ◽  
Author(s):  
Guadalupe Garrido ◽  
Anthony L Webster ◽  
Manuel Chamorro

The article describes a study that evaluated the adequacy of 2 different menu settings in a group of elite adolescent Spanish soccer players. Five-day food intake was assessed on 2 occasions, while athletes were consuming a flexible “buffet-style” diet (B; n = 33) and a fixed “menu-style” diet (M; n = 29). For all principal meals of the day food weighing was performed, and snacks were recorded by self-report. M provided significantly higher total energy and carbohydrate intakes than B. Breakfast and snacks both provided more energy in M. Calories obtained from fat were excessive in both settings. Calcium and vitamin D were below recommendations in B but not in M. Fiber, magnesium, folate, vitamin A, and vitamin E intake fell below recommended values in both settings. M provided significantly greater quantities of magnesium and vitamins D and E. Both feeding options were far from optimal in satisfying current scientifically based recommendations for active adolescents.


Author(s):  
Trung Vinh Hoàng

Bài tổng quan sau đây nói về mối liên quan giữa đái tháo đường typ 2 (ĐTĐT2) với từng loại vitamin nói chung cũng như vitamin tổng hợp. Nồng độ các vitamin có tác dụng chống gốc tự do như vitamin A, C và E đều giảm ở BN ĐTĐ làm gia tăng các stress oxi hóa, góp phần gây bất thường chuyển hóa glucose. Mặt khác các protein mang retinol (vitamin A) còn có tác dụng điều biến tương tự như các adipokin. Mặc dù cơ chế gây giảm nồng độ các vitamin nhóm B như thiamin (vitamin B1), vitamin B6 và biotin là hoàn toàn chưa rõ song nếu bổ sung các loại đó lại có tác dụng cải thiện kiểm soát chuyển hóa ở BN ĐTĐ. Hấp thu acid folic và vitamin B12 sẽ bị giảm đi nếu sử dụng merformin kéo dài trong khi đó đây lại là thuốc lựa chọn hàng đầu để điều trị ĐTĐ chưa có biến chứng. Chính vì vậy nồng độ hai loại này bị thiếu hụt, rất cần bổ sung thường xuyên. Vitamin D đóng vai trò như là yếu tố nguy cơ (YTNC) gây biến chứng ở BN trong đó có biến chứng tim mạch. Cũng có ý kiến cho rằng vitamin K có liên quan đến chuyển hóa glucose song cần phải có thêm bằng chứng trong nghiên cứu. Việc sử dụng vitamin tổng hợp cho hiệu quả chưa rõ rệt. Tuy vậy hiện nay vẫn chưa có một chỉ định thống nhất nào về bồi phụ vitamin thiếu hụt ngoại trừ sử dụng acid folic và vitamin B12 nếu điều trị bằng metformin kéo dài.


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