scholarly journals Stability of estimated breeding values for average daily gain in Pannon White rabbits

2011 ◽  
Vol 56 (No. 8) ◽  
pp. 365-369 ◽  
Author(s):  
I. Nagy ◽  
J. Farkas ◽  
P. Gyovai ◽  
I. Radnai ◽  
Z. Szendrő

Stability of estimated breeding values for average daily gain (ADG) between 5 and 10 weeks of age was analysed for 47 242 Pannon White rabbits, reared in 7470 litters and born between 2000 and 2008. The dataset was divided into 5 successive 5-year periods: (1) 2000–2004, (2) 2001–2005, (3) 2002–2006, (4) 2003–2007, and (5) 2004–2008. Then, after selecting the appropriate part of the pedigree for these sub-datasets, genetic parameters and breeding values were estimated for ADG using REML and BLUP methods. In the applied models sex, year-month, animal and random litter effects were considered. Estimated heritabilities for all 5 periods from 1 to 5 were moderate and stable (0.28 ± 0.01, 0.28 ± 0.02, 0.29 ± 0.02, 0.27 ± 0.02, and 0.28 ± 0.02). Magnitudes of random litter effects were low and stable (0.14 ± 0.01, 0.15 ± 0.01, 0.15 ± 0.01, 0.16 ± 0.01, and 0.16 ± 0.01). After breeding value estimation the dataset of period 5 was merged pair-wise with the other periods 4, 3, 2 and 1 using an inner join. Thus only the common records of the datasets representing the periods 5-4, 5-3, 5-2, and 5-1 were included in the merged datasets. In these merged datasets each rabbit had two breeding values for ADG based on two different periods. Spearman's rank correlation coefficients were calculated between the breeding values based on the dataset of period 5 and the other periods. With the successive years the rank correlation coefficients decreased (0.989, 0.979, 0.965 and 0.924). The correlation coefficients between ranks remained moderately high, even when the proportion of the common rabbits in the merged datasets was low. However, a reasonable re-ranking occurred among the top animals. Rank correlations for the top 100 and 1000 animals varied from 0.41 to 0.55 and from 0.37 to 0.54, respectively, which could influence selection efficiency if the rolling base were used for genetic evaluation.

2010 ◽  
Vol 53 (1) ◽  
pp. 26-36 ◽  
Author(s):  
S. Bene ◽  
I. Füller ◽  
A. Fördős ◽  
F. Szabó

Abstract. Weaning weight, preweaning daily gain and 205-day weight of Hungarian Fleckvieh calves (n=8 929, bulls =4 539, heifers =4 390) born from 232 sires between 1980 and 2003 were examined. Variance, covariance components and heritability values and correlation coefficients were estimated. The effect of the maternal permanent environment on genetic parameters and breeding values were examined. Two animal models were used for breeding value estimation. The direct heritability (hd2) of weaning weight, preweaning daily gain and 205-day weight was between 0.37 and 0.42. The maternal heritability (hm2) of these traits was 0.06 and 0.07. The direct-maternal correlations (rdm) were medium and negative −0.52 and −0.74. Contribution of the maternal heritability and maternal permanent environment to phenotype is smaller than that of direct heritabilities (hm2+c2< hd2). The ratio of the variance of maternal permanent environment in the phenotypic variance (c2) changed from 3 to 6 %. Estimated breeding values changed whether the permanent environmental effect of dam wasn’t taken into consideration but the rank of the animals was not modified. The genetic value for weaning results of Hungarian Fleckvieh population has increased since 1997.


REPORTS ◽  
2020 ◽  
Vol 5 (333) ◽  
pp. 35-41
Author(s):  
K.Zh. Zhumanov ◽  
◽  
T.N. Karymsakov ◽  
M.A. Kineev ◽  
A.D. Baimukanov ◽  
...  

The aim of the research was to estimate the breeding value of the servicing bulls of the Holstein black-and-white breed according to the optimized equation of the mixed BLUP model. Within a comparative aspect, the estimation results of bulls calculated using the BLUP methodology are presented. As an object of the research, information was used on first-calf heifers (daughters of the evaluated bulls), who lactated in breeding herds of the Holstein cattle of the Republic of Kazakhstan in 2016-2017. The source was the official information analytical system (IAS) of livestock breeding of the Republic of Kazakhstan. The analysis of information on the dairy productivity of the cows-daughters of the estimated bulls was performed according to the indicators of the milk yield, the contents of fat and protein in milk, the milk fat and protein yield for 305 days of lactation and the study period. To compare the obtained results, the average values of breeding value indices, the reliability of their assessment, and the rank correlation coefficients were calculated


2007 ◽  
Vol 50 (2) ◽  
pp. 147-154
Author(s):  
H. Krejčová ◽  
N. Mielenz ◽  
J. Přibyl ◽  
L. Schüler

Abstract. In this study, random regression models with Legendre polynomials of the 2nd, 3rd and 4th degree (RR2, RR3 and RR4) are compared with regard to the estimation of breeding values for the average daily gain of Czech Pied bulls (Simmental type). The data were prepared such that a multi-trait model (MTM) could be used as reference model. For each bull, 8 repeated records or fewer were available for the testing period from the 12th to the 420th day of life. For the modeling of the expected value structure, the fixed regression coefficients of the Legendre polynomials were subordinated hierarchically to the herd-year-season effects (HYS). For the comparison of the random regression models with the reference model, rank correlations between the estimated breeding values of various animal groups were calculated and a variety of top-lists were analyzed. In general, models RR3 and RR4 returned higher rank correlations with MTM in comparison to model RR2. Additionally, the number of common animals in the 1% and 10% top-lists showed that models RR3 and RR4 are to be preferred over RR2 when it comes to the estimation of breeding values.


2019 ◽  
Vol 51 (1) ◽  
Author(s):  
Evert W. Brascamp ◽  
Piter Bijma

Abstract Background In honey bees, observations are usually made on colonies. The phenotype of a colony is affected by the average breeding value for the worker effect of the thousands of workers in the colony (the worker group) and by the breeding value for the queen effect of the queen of the colony. Because the worker group consists of multiple individuals, interpretation of the variance components and heritabilities of phenotypes observed on the colony and of the accuracy of selection is not straightforward. The additive genetic variance among worker groups depends on the additive genetic relationship between the drone-producing queens (DPQ) that produce the drones that mate with the queen. Results Here, we clarify how the relatedness between DPQ affects phenotypic variance, heritability and accuracy of the estimated breeding values of replacement queens. Second, we use simulation to investigate the effect of assumptions about the relatedness between DPQ in the base population on estimates of genetic parameters. Relatedness between DPQ in the base generation may differ considerably between populations because of their history. Conclusions Our results show that estimates of (co)variance components and derived genetic parameters were seriously biased (25% too high or too low) when assumptions on the relationship between DPQ in the statistical analysis did not agree with reality.


2012 ◽  
Vol 37 (1) ◽  
pp. 65-69 ◽  
Author(s):  
Prasath Jayakaran ◽  
Gillian M Johnson ◽  
S John Sullivan

Background and Aim: The physical asymmetries associated with a prosthesis raises the question of validity of the Sensory Organization Test (SOT) measures (equilibrium score (ES) and strategy score (SS)) in lower limb amputees. This study explores the validity of these measures in transtibial amputees by correlating with their corresponding centre of pressure (COP) excursion/velocity measures. Technique: Fifteen transtibial amputees (69.5 ± 6.5 years) completed three trials for each of the six SOT conditions. Discussion: The Spearman’s rank correlation coefficients between ESs and global COP excursion/velocity measures ranged from 0.52 to 0.71 for Conditions 1, 4 and 5, 0.79 to 0.85 for Conditions 2 and 3, and 0.39 to 0.43 for Condition 6. The coefficients for SSs ranged between 0.78 and 0.97 for Conditions 1 to 5 and 0.55 to 0.67 for Condition 6. The corresponding sound and prosthetic side COP variables demonstrated varying strengths of association with ES and SS. Clinical relevance Of the two clinical measures examined, the SSs are strongly reflective of COP excursion/velocity measures and these findings have application in the interpretation of SOT when evaluating balance in transtibial amputees.


2017 ◽  
Author(s):  
Ming Kei Chung ◽  
Kurunthachalam Kannan ◽  
Germaine M. Buck Louis ◽  
Chirag J. Patel

AbstractBACKGROUND:Along with time, variation in the exposome is dependent on the location and sex of study participants. One specific factor that may influence exposure co-variations is a shared household environment.OBJECTIVES:To examine the influence of shared household and partner’s sex in relation to the variation in 128 endocrine disrupting chemical (EDC) exposures among couples.METHODS:In a cohort comprising 501 couples trying for pregnancy, we measured 128 (13 chemical classes) persistent and non-persistent EDCs and estimated 1) sex-specific differences; 2) variance explained by shared household; and 3) Spearman’s rank correlation coefficients (rs) for females, males, and couples’ exposures.RESULTS:Sex was correlated with 8 EDCs including polyfluoroalkyl substances (PFASs) (p< 0.05). Shared household explained 43% and 41% of the total variance for PFASs and blood metals, respectively, but less than 20% for the remaining 11 EDC classes. Co-exposure patterns of the exposome were similar between females and males, with within-classrs higher for persistent and lower for non-persistent chemicals. Medianrss of polybrominated compounds and urine metalloids were 0.45 and 0.09, respectively, for females (0.41 and 0.08 for males), whereas lowerrss for these 2 classes were found for couples (0.21 and 0.04).CONCLUSIONS:Overall, sex did not significantly affect EDC levels in couples. Individual, rather than shared environment, could be a major factor influencing the co-variation of 128 markers of the exposome. Correlations between exposures are lower in couples than in individual partners and have important analytical and sampling implications for epidemiological study.


2021 ◽  
Vol 30 (2) ◽  
pp. 211-223
Author(s):  
IC Travnik ◽  
AC Sant'Anna

This study into the behaviour of domestic cats (Feliscatus) aimed to assess the relationship between behavioural expressions obtained via the Qualitative Behaviour Assessment (QBA) and quantitative outcomes of temperament tests. Four behavioural tests were used: Unfamiliar person (UP); Novel object (NO); Conspecific reaction (CR); and Food offering (FO) tests. Tests were filmed and assessed using an ethogram that included 25 discrete behavioural categories, generating quantitative information (coding method) on the existing temperament dimensions. Videos were also assessed by another observer using the QBA method, based on a list of 20 adjectives rated in visual analogue scales (rating method). Data were analysed using Principal Component Analysis. Spearman's rank correlation coefficients were used to relate the principal components (PC) of QBA to the temperament dimensions obtained with the coding method. The QBA allowed us to identify three PC, explaining 76.63% of the total variance. PC1 ranged from 'calm/relaxed/friendly' to 'tense/fearful/alert', reflecting the valence of cats' behavioural and emotional expressions towards the stimuli tested. PC2 ranged from 'indifferent' to 'agitated/active', indicating the level of emotional arousal, and PC3 ranged from 'aggressive' to 'suspicious' and could be interpreted as an axis of 'aggressiveness — caution' in response to the stimuli. The first PC obtained for each test by using the coding method was significantly correlated with the PC1 of QBA, suggesting that the variations in cats' behavioural and emotional expressions identified by QBA were correlated with the main quantitative outcomes of temperament tests traditionally applied for domestic cats. QBA could be a promising tool for identifying and differentiating cat temperament profiles. Further research is required to assess the potential use of QBA as a feasible and practical method for use in shelters.


2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Xuan Zhao ◽  
Wei Lin ◽  
Jiawei Li ◽  
Yunhui Chen ◽  
Anamica Patel ◽  
...  

Dosage is essential for studying the compatibility and effectiveness of traditional Chinese medicine. Danggui and Chuanxiong are widely used in traditional Chinese medicine for ailments and treatment of various disorders. 628 traditional Chinese medicine prescriptions containing Danggui and Chuanxiong were extracted from the self-built prescription database and screened for the three groups of prescriptions, i.e., irregular menstruation, sores, and stroke. We processed and tested the dosage of Danggui and Chuanxiong and selected the optimal copula function, Gumbel copula function, from the Archimedes function family and elliptical copula function family to establish the data model. To establish the presence of a correlation between the dose of Danggui and Chuanxiong, a graph of the joint distribution function of rank correlation coefficients, Kendall’s rank correlation coefficient and Spearman’s rank correlation coefficient, was used. Our results suggest that the model using the Gumbel copula function better reflects the correlation between the dose of Danggui and Chuanxiong. For irregular menstruation, sores, and strokes, Kendall’s rank correlation coefficients were 0.6724, 0.5930, and 0.7757, respectively, and Spearman’s correlation coefficients were 0.8536, 0.7812, and 0.9285, respectively. In all three prescription groups, the dose of Danggui and Chuanxiong was positively correlated, implying that, as the dosage of one drug increases, the dosage of the other increases as well. From the perspective of data mining and mathematical statistics, the use of the copula function model to evaluate the correlation between the prescribed dosage of the two drugs was innovative and provided a new model for the scientific interpretation of the compatibility of traditional drugs. This might also serve to guide the clinical use of traditional Chinese medicine.


2019 ◽  
Vol 32 ◽  
Author(s):  
Daniel Vicentini de Oliveira ◽  
Amanda Mansano de Souza ◽  
Áurea Gonçalves Ferreira ◽  
Mateus Dias Antunes ◽  
Natália Serra Lovato ◽  
...  

Abstract Introduction: Despite the importance of appropriate levels of muscular strength to maintain the functional capacity and a healthy life in old age, the current literature still lacks studies that investigate the profile of elderly women who practice Mat Pilates regarding these variables. Objective: This study aimed to analyze muscular strength, functional capacity, and risk of sarcopenia in elderly women who practiced Mat Pilates. Method: This is a cross-sectional study carried out with 50 elderly women who practice Mat Pilates in the city of Maringá, Paraná. Sociodemographic and health questionnaires were used, in addition to tests created by a Latin American development group for maturity called Grupo de Desenvolvimento Latino Americano para a Maturidade (GDLAM), sitting-rising test, arm curl test, and SARC-F questionnaire. For data analysis, Shapiro-Wilk and Mann-Whitney U tests, as well as Spearman’s Rank Correlation Coefficients, were used. The level of significance was p < 0.05. Results: The 70-79-year-old elderly women showed worse results in the functional capacity and muscular strength tests of the upper limbs and a higher risk of sarcopenia than the individuals who were under 70 years of age. Muscular strength was inversely related to the reduction of the risk of sarcopenia, and functional capacity was directly associated with this risk. Conclusion: A good functional capacity seems to be related to the reduction of the risk of sarcopenia. Age seems to be an intervening factor for reducing muscular strength levels and functional capacity and increasing the risk of sarcopenia.


2019 ◽  
Vol 56 (1) ◽  
pp. 12-25
Author(s):  
Carolina Bermejo ◽  
Federico Cazzola ◽  
Fernando Maglia ◽  
Enrique Cointry

AbstractThe most important objective of lentil breeding programs is to develop new genotypes that are genetically more productive. Besides, it is necessary that the varieties obtained have short flowering cycles to allow the later sowing of summer crops. Selection is based through phenotypic means; however, we argue it should be based on genetic or breeding values because quantitative traits are often influenced by environments and genotype–environment interactions. The objectives of this study were to: (i) identify genotypes with the highest merit; (ii) estimate genetic parameters to know the genetic control of morphological traits in macrosperma and microsperma lentil types using best linear unbiased prediction (BLUP). Twenty-five recombinant inbred lines (RILs) from six F4 families selected on the basis of precocity and high yields were tested in four environments for important quantitative traits. The analysis of variance showed significant differences between genotypes, environments, and genotype–environment interactions for all the traits. Seven macrosperma- and two microsperma-type RILs were selected. Based on average ranking from breeding values and molecular data obtained with sequence-related amplified polymorphism (SRAP), the same genotypes were selected. Genotypic coefficients of variation, heritability across and by environment, and genetic correlation coefficients using BLUP were obtained. According to our results BLUP could replace molecular analysis methods because the selection process was simpler, more cost-effective, and more accurate. The breeding value of parents would give a better ranking of their genetic value than would their phenotypic value; therefore, the selection efficiency would be enhanced and the genetic gain would be more predictable. The selected genotypes could become potential commercial varieties or be used as parental lines in future hybridization programs.


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