scholarly journals Tissue fatty acid deposition, plasma lipid and cytokine profile in pigs fed a diet with fish oil or palm oil

2017 ◽  
Vol 62 (No. 11) ◽  
pp. 482-490 ◽  
Author(s):  
T. Komprda ◽  
V. Rozíková ◽  
M. Vícenová ◽  
N. Procházková ◽  
P. Ondráčková ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fish Oil ◽  
Inflammatory Cytokines ◽  
Acid Deposition ◽  
Palm Oil ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Cytokine Profile ◽  
Lipoprotein Cholesterol ◽  
Dietary Fish

The present study tested a hypothesis concerning a favourable effect of dietary fish oil on the tissue polyunsaturated fatty acid (PUFA) deposition, and on plasma lipid and cytokine profile. Thirty-two pigs divided into two groups of 16 animals each were fed for 70 days a diet with 2.5% of fish oil (F) and palm oil (P), respectively. The content of PUFA n-3 in the liver, muscle (m. quadriceps femoris), and visceral adipose tissue (VAT) of the F- and P-pigs was 530 and 129, 84 and 19, 1365 and 191 mg/100 g of the fresh tissue, respectively (differences between dietary groups were significant at P < 0.01 in all tissues). Dietary fish oil in comparison with palm oil decreased (P < 0.05) total plasma cholesterol, but also desirable high-density lipoprotein cholesterol, and had no effect (P > 0.05) both on low-density lipoprotein cholesterol and triacylglycerols. Moreover, dietary fish oil increased (P < 0.05) expression of the genes coding for not only anti-inflammatory cytokines IL-10 (P < 0.01) and TGF-β1 (P < 0.05), but also for pro-inflammatory cytokines IL-6 (P < 0.01), IL-12, and TNF-α (P < 0.05) in the VAT, and increased (P < 0.05) the expression of the IL6 gene in the liver. On the other hand, no significant differences (P > 0.05) between the F- and P-pigs in plasma levels of any tested cytokine were found out. It was concluded that an effect of dietary fish oil on tissue fatty acid deposition is undeniable, but its effects on plasma markers related to the risk of chronic degenerative diseases require further research.

scholarly journals The effect of dietary fatty acid composition on the hepatic fatty acid content and plasma lipid profile in rats

2015 ◽  
Vol 84 (2) ◽  
pp. 197-207
Author(s):  
Tomáš Komprda ◽  
Veronika Rozíková ◽  
Barbora Němcová ◽  
Branislav Ruttkay-Nedecký
Keyword(s):  
Fatty Acid ◽  
Acid Content ◽  
Fatty Acid Content ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Dietary Lipids ◽  
Lipoprotein Cholesterol ◽  
Male Rats ◽  
Feed Mixture ◽  
Hepatic Fatty Acid

The objective of the present study was to evaluate in a model organism the effect of different dietary lipids on plasma concentration of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triacylglycerols (TAG). One hundred adult male rats (Wistar Albino) were divided into 10 groups with 10 animals each and fed for 7 weeks either basic feed mixture (control diet, C) or basic feed mixture with 5% of palm oil (P), safflower oil (SF), salmon oil (S), fish oil (F), Schizochytrium microalga oil (A), and 20% of beef tallow (T; four groups), respectively. The T-groups were fed for another 7 weeks T-, SF-, F- and A-diet, respectively. At the end of both the first and the second 7-week fattening period, plasma lipid concentration and hepatic fatty acid content was determined. Both A and F diets fed for 7 weeks decreased (P < 0.05) plasma TC (0.98 mmol∙l-1) compared to control (1.19 mmol∙l-1). The highest (P < 0.05) plasma TC was established in rats fed for 7 weeks the SF-diet following the previous 7-week T-treatment (2.15 mmol∙l-1). A-diet had the most positive (decreasing) effect on TAG concentrations (0.68–0.86 mmol∙l-1 compared to 1.22 and 2.88 mmol∙l-1 found in the C and T diets, respectively; P < 0.05). Both plasma TC and TAG were in a negative relationship (P < 0.01) with the hepatic eicosapentaenoic acid and docosahexaenoic acid (DHA) contents, respectively. It was concluded that dietary Schizochytrium microalga oil (with high DHA content) may have the potential for decreasing the risk of cardiovascular diseases.

Dietary Fish Oil Alters Rat Milk Composition and Liver and Brain Fatty Acid Composition of Fetal and Neonatal Rats

1993 ◽  
Vol 123 (10) ◽  
pp. 1703-1708 ◽  
Author(s):  
Akie Yonekubo ◽  
Shyuji Honda ◽  
Mariko Okano ◽  
Kayoko Takahashi ◽  
Yoshiro Yamamoto
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Fish Oil ◽  
Acid Composition ◽  
Milk Composition ◽  
Neonatal Rats ◽  
Dietary Fish
Sign in / Sign up

Export Citation Format

Share Document