scholarly journals Trace metal ions release from fixed orthodontic appliances and DNA damage in oral mucosa cells by in vivo studies: A literature review

2017 ◽  
Vol 26 (7) ◽  
pp. 1155-1162 ◽  
Author(s):  
Patrycja Downarowicz ◽  
Marcin Mikulewicz
Keyword(s):  
Dna Damage ◽  
Literature Review ◽  
Trace Metal ◽  
Metal Ions ◽  
Oral Mucosa ◽  
In Vivo Studies ◽  
Orthodontic Appliances ◽  
Trace Metal Ions ◽  
Fixed Orthodontic Appliances

scholarly journals Review of the local tissue reaction to metallic spinal implant debris: Ions and nanoparticles

2021 ◽  
Vol 9 (3) ◽  
pp. 167-187
Author(s):  
Magdalena Richter ◽  
Henryk Matusiewicz
Keyword(s):  
Trace Metal ◽  
Metal Ions ◽  
Tissue Reaction ◽  
The Body ◽  
Trace Metal Ions ◽  
Local Tissue ◽  
Local Tissue Reaction ◽  
Bodily Fluids ◽  
Wear Products

Biologic reactivity to implant debris is the primary determinant of long-term clinical performance. The metallic implants placed in human bodies can exhibit electrochemical or mechanical corrosion that yields in the liberation of metallic products. Such implants-derived metal wear products can be present in the form of metal ions and particulate metal debris with still unknown effects on human health. In situ generation of metallic wear particles, corrosion products and in vivo trace metal ions release from metal and metallic alloys implanted into the body in spine surgery is becoming a major cause for concern regarding the health and safety of patients. In vivo clinical studies addressing the adverse local tissue reaction effects of metallic wear products on surrounding soft tissues and bodily fluids are less numerous. Although numerous studies have focused on the clinical significance of corrosion and wear of hip and knee replacements, research involving spine instrumentation is not well documented. This review explores how migration of metallic wear nanoparticles and trace metal ions in the area of metallic spinal implants influences the surrounding tissues and bodily fluids, and what the clinical consequences of this process may be.

scholarly journals In vivo Study on Release of Nickel, Chromium, and Zinc and DNA Damage in Buccal Mucosa Cells from Patients Treated with Fixed Orthodontic Appliances

2018 ◽  
Vol 52 (2) ◽  
pp. 115-119
Author(s):  
Dilip Daniel Quadras ◽  
U S Krishna Nayak ◽  
N Suchetha Kumari ◽  
H R Priyadarshini ◽  
Srinivasa Gowda ◽  
...  
Keyword(s):  
Dna Damage ◽  
Buccal Mucosa ◽  
In Vivo Study ◽  
Orthodontic Appliances ◽  
Nickel Chromium ◽  
Buccal Mucosa Cells ◽  
Fixed Orthodontic Appliances

In vivo Study on Release of Nickel, Chromium, and Zinc and DNA Damage in Buccal Mucosa Cells from Patients Treated with Fixed Orthodontic Appliances

2018 ◽  
Vol 52 (2) ◽  
pp. 115-119
Author(s):  
Dilip Daniel Quadras ◽  
U S Krishna Nayak ◽  
N Suchetha Kumari ◽  
H R Priyadarshini ◽  
Srinivasa Gowda ◽  
...  
Keyword(s):  
Dna Damage ◽  
Buccal Mucosa ◽  
In Vivo Study ◽  
Orthodontic Appliances ◽  
Nickel Chromium ◽  
Buccal Mucosa Cells ◽  
Fixed Orthodontic Appliances

scholarly journals Potentially toxic metallic wear nanoparticles and trace metal ions release from metal-on-metal orthopedic implants in the human biological specimens: An Overview of in vivo and ex vivo clinical studies

2020 ◽  
Vol 8 (3) ◽  
pp. 242-292
Author(s):  
Henryk Matusiewicz ◽  
Magdalena Richter
Keyword(s):  
Trace Metal ◽  
Metal Ions ◽  
Ex Vivo ◽  
Orthopedic Implants ◽  
The Body ◽  
Trace Metal Ions ◽  
Bodily Fluids ◽  
Metal On Metal

The use of metallic biomaterials in the medical implant devices has become increasingly prevalent over the past few decades. Patients find themselves being exposed to metals in a variety of ways, ranging from external exposure to instruments such as medical devices to internal exposure via surgical devices being implanted in their bodies. In situ generation of metallic wear nanoparticles, corrosion products and in vivo trace metal ions release from metal and metallic alloys implanted into the body in orthopedic surgery is becoming a major cause for concern regarding the health and safety of patients. The chemical form, particulate vs. ionic, of the metal species in the bodily fluids and tissues is a key to the local nanotoxicity effects arising in the body. Potential health risks are associated with metallic wear debris in the form of nanoparticles in situ generation and the release of in vivo trace metal ions into human biological specimen's circulation. This overview explores how migration of metallic wear nanoparticles and ultratrace metal ions in the area of metal-on-metal orthopedic implants influences the surrounding tissues and bodily fluids, and what the toxicological consequences of this process may be. Specifically, the present article is more informative of indicative multilevel in situ/in vivo/ex vivo analytical/clinical methodologies which will be helpful in a way to plan, understand and lead the analytical innovations in the area of nano-analysis to improve patient outcomes.

scholarly journals Infiltration of trace metal ions in the oral mucosa of a rat analyzed using SRXRF, XAFS, and ICP-MS

2015 ◽  
Vol 34 (6) ◽  
pp. 814-821 ◽  
Author(s):  
Toshihiro IMAMURA ◽  
Zuisei KANNO ◽  
Haruki IMAI ◽  
Tomoko SUGIYAMA ◽  
Takahiro WADA ◽  
...  
Keyword(s):  
Trace Metal ◽  
Metal Ions ◽  
Oral Mucosa ◽  
Trace Metal Ions ◽  
Icp Ms
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