scholarly journals Protective and therapeutic effects of pyrrolidine dithiocarbamate in a rat tongue cancer model created experimentally using 4-nitroquinoline 1-oxide

2020 ◽  
Vol 29 (11) ◽  
pp. 1249-1254
Author(s):  
Aysenur Hafız ◽  
Remzi Doğan ◽  
Zuhal Gucin ◽  
Omer Ozer ◽  
Alper Yenigun ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Pyrrolidine Dithiocarbamate ◽  
Therapeutic Effects ◽  
Cancer Model ◽  
Rat Tongue

scholarly journals Therapeutic effects of adoptive splenocyte transfer following in situ AdIL-12 gene therapy in a mouse prostate cancer model

2005 ◽  
Vol 13 (1) ◽  
pp. 91-98 ◽  
Author(s):  
T Saika ◽  
N Kusaka ◽  
V Mouraviev ◽  
T Satoh ◽  
H Kumon ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Gene Therapy ◽  
Therapeutic Effects ◽  
Cancer Model ◽  
Mouse Prostate ◽  
Prostate Cancer Model

Correlation of P-cadherin and β-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide

Oral Oncology ◽  
2003 ◽  
Vol 39 (5) ◽  
pp. 506-514 ◽  
Author(s):  
Isao Tamura ◽  
Toshio Sakaki ◽  
Brahim Chaqour ◽  
Pamela S Howard ◽  
Takashi Ikeo ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Rat Tongue

Novel OK-432-conjugated Tumor Vaccines Induce Tumor-specific Immunity against Murine Tongue Cancer

2003 ◽  
Vol 82 (8) ◽  
pp. 636-640
Author(s):  
X. Li ◽  
H. Bukawa ◽  
M. Hirota ◽  
Y. Tsuyuki ◽  
S. Omura ◽  
...  
Keyword(s):  
Tumor Antigens ◽  
Tongue Cancer ◽  
Cytolytic Activity ◽  
Cancer Model ◽  
Tumor Vaccines ◽  
Antitumor Effects ◽  
Growth And Survival ◽  
Specific Immunity ◽  
Streptococcal Preparation ◽  
Histological Results

Priming with tumor antigens is one of the most important strategies in cancer immunotherapy. To enhance tumor antigenicity, OK-432, a streptococcal preparation, was coupled to squamous cell carcinoma (KLN-205) by means of a 0.2% glutaraldehyde method. The purpose of this study was to investigate whether OK-432-conjugated tumor vaccines could induce tumor-specific immunity. Our originally developed mouse tongue cancer model was used throughout this work for the analysis of antitumor effects. Prepared OK-432-conjugated KLN-205 vaccines were immunized 3 times to DBA/2 mice. The results showed that the KLN-205 vaccines induced cytolytic activity and strongly suppressed both KLN-205 tumor incidence and growth, and survival of the mice was improved. Moreover, the histological results showed that a greater number of lymphocytes had infiltrated around tumor cells by 24 hours after tumor inoculation in the vaccine group. These results suggest that immunizations with KLN-205 vaccines increase the antitumor effects against tongue cancer.

The Measurement of Singlet Oxygen Production in an Experimental Tongue Cancer Model as an Indicator for Photodynamic Therapy

2013 ◽  
Vol 136 (0) ◽  
pp. 62-69
Author(s):  
Ying-Ying Wu ◽  
Toru Hirano ◽  
Junko Yamamoto ◽  
Guang-Wu Huang ◽  
Seiji Yamamoto ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Tongue Cancer ◽  
Oxygen Production ◽  
Cancer Model

Identification and characterization of a highly metastatic epithelial cancer cell line from rat tongue cancer

2018 ◽  
Vol 95 ◽  
pp. 58-67
Author(s):  
Xing Qin ◽  
Ming Yan ◽  
Rongrong Li ◽  
Dongxia Ye ◽  
Jianjun Zhang ◽  
...  
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Tongue Cancer ◽  
Cancer Cell Line ◽  
Epithelial Cancer ◽  
Rat Tongue ◽  
Identification And Characterization

Sympathectomy suppresses tumor growth and alters gene-expression profiles in rat tongue cancer

2009 ◽  
Vol 117 (4) ◽  
pp. 351-361 ◽  
Author(s):  
Bina Raju ◽  
Michael Hultström ◽  
Sivakami R. Haug ◽  
Salah O. Ibrahim ◽  
Karin J. Heyeraas
Keyword(s):  
Gene Expression ◽  
Tumor Growth ◽  
Tongue Cancer ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Rat Tongue

Rapid tumor necrosis induced by electrochemotherapy with intratumoral injection of bleomycin in a hamster tongue cancer model

2000 ◽  
Vol 29 (2) ◽  
pp. 119-125
Author(s):  
Susumu Omura ◽  
Yoshiharu Tsuyuki ◽  
Shinsuke Ohta ◽  
Xianqi Li ◽  
Hiroki Bukawa ◽  
...  
Keyword(s):  
Tumor Necrosis ◽  
Tongue Cancer ◽  
Intratumoral Injection ◽  
Cancer Model

scholarly journals Therapeutic Efficacy of Orally Delivered Doxorubicin Nanoparticles in Rat Tongue Cancer Induced by 4-Nitroquinoline 1-Oxide

2015 ◽  
Vol 5 (2) ◽  
pp. 209-216 ◽  
Author(s):  
Monir Moradzadeh Khiavi ◽  
Ahamd Rostami ◽  
Hamed Hamishekar ◽  
Mehran Mesgari Abassi ◽  
Amirala Aghbali ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Tongue Cancer ◽  
Rat Tongue
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