NMR techniques in Cultural Heritage

2019 ◽  
pp. 158-176

Author(s):  
W.A. Jacob ◽  
R. Hertsens ◽  
A. Van Bogaert ◽  
M. De Smet

In the past most studies of the control of energy metabolism focus on the role of the phosphorylation potential ATP/ADP.Pi on the regulation of respiration. Studies using NMR techniques have demonstrated that the concentrations of these compounds for oxidation phosphorylation do not change appreciably throughout the cardiac cycle and during increases in cardiac work. Hence regulation of energy production by calcium ions, present in the mitochondrial matrix, has been the object of a number of recent studies.Three exclusively intramitochondnal dehydrogenases are key enzymes for the regulation of oxidative metabolism. They are activated by calcium ions in the low micromolar range. Since, however, earlier estimates of the intramitochondnal calcium, based on equilibrium thermodynamic considerations, were in the millimolar range, a physiological correlation was not evident. The introduction of calcium-sensitive probes fura-2 and indo-1 made monitoring of free calcium during changing energy metabolism possible. These studies were performed on isolated mitochondria and extrapolation to the in vivo situation is more or less speculative.


Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
J Tchoumtchoua ◽  
M Halabalaki ◽  
D Njamen ◽  
J Mbanya ◽  
L Skaltsounis

1997 ◽  
pp. 33-36
Author(s):  
Anatoliy Moskovchuk

Ukraine is the motherland of not only Ukrainians but also of many national minorities with different cultures and traditions. Ukraine is a Christian country in general, with non-Christian and non-Christian religions and confessional currents, along with traditional churches - Orthodox, Catholic, Protestant - rooted and actively developing non-traditional Ukrainian culture and spirituality. In Ukraine there is a complex process of spiritual revival, especially in the intellectual environment. Many are written and talk about the preservation of cultural heritage. Everywhere, monuments of architecture, art, which testify to the generally recognized historical contribution of Christianity to the development of spirituality and morality of the Ukrainian people, are restored. In our eyes, there are changes in social and religious relations.


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