scholarly journals The Efficacy of Greater Occipital Nerve Block in Patients With Chronic Migraine

2021 ◽  
Author(s):  
Meltem KARACAN GÖLEN ◽  
Dilek YILMAZ OKUYAN
Keyword(s):  
Chronic Migraine ◽  
Nerve Block ◽  
Occipital Nerve ◽  
Greater Occipital Nerve Block ◽  
Greater Occipital Nerve ◽  
Occipital Nerve Block

Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic migraine patients?

2017 ◽  
Vol 38 (6) ◽  
pp. 949-954 ◽  
Author(s):  
Hanzade Aybüke Ünal-Artık ◽  
Levent Ertuğrul İnan ◽  
Ceyla Ataç-Uçar ◽  
Tahir Kurtuluş Yoldaş
Keyword(s):  
Chronic Migraine ◽  
Nerve Block ◽  
Occipital Nerve ◽  
Greater Occipital Nerve Block ◽  
Greater Occipital Nerve ◽  
Occipital Nerve Block

scholarly journals Predictors of response to occipital nerve stimulation in refractory chronic headache

Cephalalgia ◽  
2017 ◽  
Vol 38 (7) ◽  
pp. 1267-1275 ◽  
Author(s):  
Sarah Miller ◽  
Laurence Watkins ◽  
Manjit Matharu
Keyword(s):  
Chronic Migraine ◽  
Nerve Block ◽  
Nerve Stimulation ◽  
Chronic Headache ◽  
Occipital Nerve Stimulation ◽  
Occipital Nerve ◽  
Greater Occipital Nerve Block ◽  
Predictors Of Response ◽  
Greater Occipital Nerve ◽  
Occipital Nerve Block

Background Occipital nerve stimulation is a promising treatment for refractory chronic headache disorders, but is invasive and costly. Identifying predictors of response would be useful in selecting patients. We present the results of an open-label prospective cohort study of 100 patients (35 chronic migraine, 33 chronic cluster headache, 20 short-lasting unilateral neuralgiform headache attacks and 12 hemicrania continua) undergoing occipital nerve stimulation, using a multivariate binary regression analysis to identify predictors of response. Results Response rate of the cohort was 48%. Multivariate analysis showed short lasting unilateral neuralgiform headache attacks (OR 6.71; 95% CI 1.49–30.05; p = 0.013) and prior response to greater occipital nerve block (OR 4.22; 95% CI 1.35–13.21; p = 0.013) were associated with increased likelihood of response. Presence of occipital pain (OR 0.27; 95% CI 0.09–0.76; p = 0.014) and the presence of severe anxiety and/or depression (as measured on hospital anxiety and depression score) at time of implantation (OR 0.32; 95% CI 0.11–0.91; p = 0.032) were associated with reduced likelihood of response. Conclusion Possible clinical predictors of response to occipital nerve stimulation for refractory chronic headaches have been identified. Our data shows that those with short-lasting unilateral neuralgiform headache attacks respond better than those with chronic migraine, and that a prior response to greater occipital nerve block is associated with positive outcomes. This study suggests that the presence of occipital pain and severe mood disorder at time of implant are both associated with poor outcomes to occipital nerve stimulation.

scholarly journals Erratum to: Greater occipital nerve block in chronic migraine

2011 ◽  
Vol 32 (3) ◽  
pp. 535-535 ◽  
Author(s):  
Maria Gabriella Saracco ◽  
W. Valfrè ◽  
M. Cavallini ◽  
M. Aguggia
Keyword(s):  
Chronic Migraine ◽  
Nerve Block ◽  
Occipital Nerve ◽  
Greater Occipital Nerve Block ◽  
Greater Occipital Nerve ◽  
Occipital Nerve Block

scholarly journals THE EFFICACY OF GREATER OCCIPITAL NERVE BLOCK IN PATIENTS WITH CHRONIC MIGRAINE

2021 ◽  
Author(s):  
Meltem KARACAN GÖLEN ◽  
Dilek YILMAZ OKUYAN
Keyword(s):  
Medical Treatment ◽  
Chronic Migraine ◽  
Nerve Block ◽  
Occipital Nerve ◽  
Greater Occipital Nerve Block ◽  
Greater Occipital Nerve ◽  
Scale Scores ◽  
Occipital Nerve Block ◽  
Keywords Headache ◽  
Analgesic Use

Background and Purpose: In chronic migraines(CM), the rate of benefiting from medical treatment is relatively low, and it is known that patients use analgesics extensively. Greater occipital nerve (GON) block, have been started to be used in chronic migraine patients who were refractory to treatment. In this study, we aimed to evaluate the headache attack frequency, analgesic use, VAS (Visual Analog Scale) and MIDAS (Migraine Disability Assessment Scale) scores in the 3-month follow-up of patients we had performed a GON block in our clinic for chronic migraine refractory to medical treatment. Methods: A total of 120 CM patients were included in the study. The number of analgesics used, the number of days with pain, and the VAS and MIDAS scores were recorded before the GON block and at one and three months of treatment. Results: There was a statistically significant (p<0.001*) reduction in the number of days with pain, analgesic use, and the VAS and MIDAS scores in the first and third months compared to the pre-treatment baseline values in patients who had undergone a GON block. No significant differences between the first and third months. Conclusions: After the GON block, we noted a significant reduction of headaches and improved quality of life in patients who had been experiencing severe headaches despite medical treatment. The GON block has an exceptionally high benefit rate, might be considered as a treatment option before migraines gain chronicity, patients are not exposed to an excessive medical burden and increased treatment costs. Keywords: Headache; Chronic migraine; Greater occipital nerve block.

RETRACTED ARTICLE: Greater occipital nerve block in chronic migraine

2010 ◽  
Vol 31 (S1) ◽  
pp. 179-180 ◽  
Author(s):  
Maria Gabriella Saracco ◽  
W. Valfrè ◽  
M. Cavallini ◽  
M. Aguggia
Keyword(s):  
Chronic Migraine ◽  
Nerve Block ◽  
Occipital Nerve ◽  
Greater Occipital Nerve Block ◽  
Greater Occipital Nerve ◽  
Retracted Article ◽  
Occipital Nerve Block

scholarly journals Effect of Ultrasound Guided Bilateral Greater Occipital Nerve Block on Serum Calcitonin Gene Related Peptide (CGRP) in Chronic Migraine

2021 ◽  
Vol 10 (1) ◽  
pp. 01-05
Author(s):  
Abdelrahman Atef ◽  
Mahmoud Haroun ◽  
Ali Soliman ◽  
Ramez Mostafa ◽  
Ahmed Elsadek ◽  
...  
Keyword(s):  
Chronic Migraine ◽  
Nerve Block ◽  
Calcitonin Gene Related Peptide ◽  
Ultrasound Guided ◽  
Occipital Nerve ◽  
Related Peptide ◽  
Greater Occipital Nerve Block ◽  
Calcitonin Gene ◽  
Greater Occipital Nerve ◽  
Occipital Nerve Block

Background: The trigeminal ganglion plays a key role in primary headache pathophysiology. Calcitonin gene-related peptide (CGRP) and CGRP receptors are expressed in trigeminal neurons that form C-fibers and A-fibers, respectively. In migraine attacks, there is release of CGRP into the cranial venous outflow, in refractory headache to conventional pharmacologic management, minimally invasive techniques such as greater occipital nerve block (GONB) are feasible for pain relief, and help to decrease the frequency of the attacks, Studies on the ultrasound (US) guided GON injection technique have emphasized that this technique has a higher success rate and should allow for a more precise block of the nerve. Our study will be concerned by correlation of CGRP level as a biomarker for effectiveness and responders of us guided GON block in chronic migraine (CM). Methods: twenty patients diagnosed with chronic migraine were recruited in this study. All participants underwent ultrasound-guided bilat. GONB by 40 mg triamcinolone and 1 cc leidocaine using a portable ultrasound system with a 7 – 13 MHz multifrequency transducer, blood samples were collected from antecubital vein immediately before and three to five weeks after injection clinical response was evaluated using headache diaries Results: CGRP levels after ultrasound guided GONB (median, 40 pg/mL; range, 25-60) were significantly lower as compared with CGRP levels obtained before GONB (median, 145 pg/mL; range, 60-380; P =0.001). Pretreatment CGRP levels in non-responders (310 pg/mL) were significantly higher than those seen in responders being in poor responders less than 50% improvement (135 pg/ml) and good responders (140 pg/mL; P = 0.003). One month after treatment. A number of demographic factors, clinical features, and comorbidities were not different in responders as compared with those of nonresponders. Conclusion: These results suggests that interictal CGRP levels can be of help in predicting the response to GONB and suggest that the mechanism of action of GONB in CM is the reversal of sensitization as a result of the inhibition of CGRP release still more studies needed to highlight CGRP role with GONB

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