scholarly journals Comparison Of Pro-BNP Levels And Myocardial Performance Index Before And After Iron Treatment In Children With Congenital Cyanotic Heart Disease With Iron Deficiency Anemia

2019 ◽  
Author(s):  
Adnan Barutçu ◽  
Sevcan Erdem ◽  
Fadli Demir ◽  
Saliha Barutçu ◽  
Göksel Leblebisatan
Keyword(s):  
Heart Disease ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Performance Index ◽  
Deficiency Anemia ◽  
Myocardial Performance ◽  
Cyanotic Heart Disease ◽  
Iron Treatment ◽  
Before And After ◽  
Congenital Cyanotic Heart Disease

THE GASTROINTESTINAL EFFECTS OF IRON-DEFICIENCY ANEMIA

PEDIATRICS ◽  
1964 ◽  
Vol 33 (1) ◽  
pp. 83-99
Author(s):  
J. L. Naiman ◽  
F. A. Oski ◽  
L. K. Diamond ◽  
G. F. Vawter ◽  
H. Shwachman
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Control Group ◽  
Poor Correlation ◽  
Iron Treatment ◽  
High Incidence ◽  
Before And After ◽  
And Function ◽  
Duodenal Biopsies

A group of 14 infants and children with nutritional iron-deficiency anemia were studied with respect to gastrointestinal function and structure both before and after iron treatment. A high incidence of abnormalities was found, consisting of gastric achlorhydria, impaired absorption of xylose and vitamin A, and steatorrhea. Duodenal biopsies revealed varying degrees of chronic duodenitis and mucosal atrophy. There was poor correlation between structure and function. Following treatment with oral iron most of the abnormalities reverted to normal. A control group of 8 children with long-standing anemias not due to iron deficiency were subjected to similar studies, most of which yielded normal results. These observations indicate a diffuse and reversible enteropathy in children as a result of iron deficiency. The pathogenesis and practical implications are discussed.

scholarly journals Kidney injury in infants and children with iron-deficiency anemia before and after iron treatment

Hematology ◽  
2017 ◽  
Vol 22 (9) ◽  
pp. 565-570 ◽  
Author(s):  
Rasha H. Hassan ◽  
Shaimaa M. Kandil ◽  
Mayada S. Zeid ◽  
Maysaa E. Zaki ◽  
Ashraf E. Fouda
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Kidney Injury ◽  
Infants And Children ◽  
Deficiency Anemia ◽  
Iron Treatment ◽  
Before And After ◽  
In Infants And Children

scholarly journals 839 Iron Deficiency Anemia in Children with Congenital Heart Disease

2010 ◽  
Vol 68 ◽  
pp. 421-421
Author(s):  
A Maloku-Ceku ◽  
M Berisha ◽  
R Bejiqi ◽  
R Retkoceri
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Congenital Heart ◽  
Deficiency Anemia

scholarly journals Excess Hemolysis in Subjects with Severe Iron Deficiency Anemia Associated and Nonassociated with Hookworm Infection

Blood ◽  
1965 ◽  
Vol 25 (1) ◽  
pp. 73-91 ◽  
Author(s):  
MIGUEL LAYRISSE ◽  
JESÚS LINARES ◽  
MARCEL ROCHE ◽  
Adelina Ojeda ◽  
Alvaro Carstens ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Cell Survival ◽  
Iron Deficiency Anemia ◽  
Red Cells ◽  
Deficiency Anemia ◽  
Intrinsic Defect ◽  
Red Cell ◽  
Hookworm Infection ◽  
Iron Treatment ◽  
Red Cell Survival

Abstract An excess hemolysis was found in subjects with iron deficiency anemia associated with hookworm infection. Red cell survival, measured with Cr51 and DFP32 in the subjects before deworming, showed a marked disproportion between the decrease of the survival and the amount of daily intestinal blood loss in most cases. Excess of hemolysis was still present after more than 90 per cent of the parasites were removed. Red cell survival became normal after correction of anemia through iron treatment. Excess of hemolysis was also present in noninfected subjects with iron deficiency anemia due to other causes. The reduction in the survival of the erythrocytes from infected subjects transfused into normal recipients shows that the hemolytic process is due to an intrinsic defect of the red cells. The low values of hemoglobinemia and the presence of haptoglobins in the plasma indicate that hemoglobin has not been liberated in excess intravascularly. Finally, the fact that the red cells from an infected patient taken after deworming survived normally in splenectomized recipients indicates that the spleen is probably the principal site of the red cell destruction. The clinical and autopsy findings suggest that splenic function is not pathologically increased, but rather that this organ is acting physiologically at a more rapid rate, "culling" the abnormal circulating red cells and thus leading to a decrease in red cell survival. The studies presented here also indicate that the hookworm infection per se does not induce hemolysis.

scholarly journals Urinary Iron Excretion in Valvular Heart Disease and After Heart Valve Replacement

Blood ◽  
1970 ◽  
Vol 36 (6) ◽  
pp. 785-792 ◽  
Author(s):  
H. PETER ROESER ◽  
L. W. POWELL
Keyword(s):  
Heart Disease ◽  
Iron Deficiency ◽  
Valve Replacement ◽  
Valvular Heart Disease ◽  
Serum Iron ◽  
Normal Values ◽  
Iron Loss ◽  
Deficiency Anemia ◽  
Before And After ◽  
Iron Excretion

Abstract Urinary iron excretion and other aspects of iron metabolism were studied in patients with valvular heart disease before and after valve replacement with heterografts or Starr-Edwards prostheses. Eighty-one per cent of preoperative patients had increased daily urinary iron excretion (0.14-2.2 mg./24 hours) and 61 per cent had a reduced 51Cr survival time. Serum iron levels were low in two patients but iron-deficiency anemia was not observed. Fifty-three per cent of bone marrow aspirates had reduced or absent storage iron. Patients with normally functioning heterografts had no hemolysis and urinary iron excretion decreased exponentially with time until normal values were reached in 6-10 months after surgery. Calculated iron loss over a 6-month postoperative period varied from 11 to 360 mg. Serum iron levels and results of ferrokinetic studies returned towards normal, as did marrow iron stores. Seven patients (78%) with Starr-Edwards valves had evidence of hemolysis by the 51chromium survival method and six were anemic. Urinary iron loss was abnormal in all nine patients (0.8-10.8 mg./24 hours) and iron deficiency was a significant factor in the anemia noted. Iron therapy raised hemoglobin values in the two patients to whom it was administered. Urinary iron excretion was found to be a sensitive index of intravascular hemolysis, particularly in the presence of an intermittent hemolytic process.

Investigation of ischemia modified albumin levels in iron deficiency anemia

2017 ◽  
Vol 42 (3) ◽  
Author(s):  
Sibel Bilgili ◽  
Giray Bozkaya ◽  
Funda Kırtay Tütüncüler ◽  
Murat Akşit ◽  
Mehmet Yavuz
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Binding Capacity ◽  
Oral Iron ◽  
Deficiency Anemia ◽  
Control Group ◽  
Ischemia Modified Albumin ◽  
Before And After ◽  
Anemia Group

AbstractObjective:The aim of this study was to evaluate the levels of ischemia-modified albumin (IMA), before and after oral iron supplementation in iron deficiency anemia and to determine the correlations between IMA and hemoglobin values.Study design:IMA, hemoglobin, hematocrit, mean corpuscular volume, ferritin, iron, total iron binding capacity and albumin levels were measured in 140 female patients with newly established as iron deficiency anemia before and after treatment and in 84 female healthy controls.Results:IMA levels were higher in the anemia group [0.340±0.082 absorbance units (ABSU)] compared to control group (0.291±0.077 ABSU). After oral iron therapy we saw that IMA values (0.392±0.080 ABSU) were higher than the IMA levels of the anemia group and the control group (p<0.05). Only in the anemia group there were negative correlations between IMA and hemoglobin, hematocrit.Conclusion:We conclude that the high levels of IMA in the anemia group might be attributed to hypoxia due to low hemoglobin levels. Iron is an oxidant element and oral iron supplementation may be associated with oxidative stress and may increase IMA levels by changing the albumin molecule. We thought that, IMA can be demonstrative of the severity of anemia since it was correlated with hemoglobin in the anemia group.

scholarly journals Long-term Effect of Intravenous Iron Carboxymaltose Treatment on Oxidative Stress in Women with Iron Deficiency Anemia

2021 ◽  
pp. 3-10
Author(s):  
Gökhan Pektaş ◽  
İsmail Kırlı
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Catalase Activity ◽  
Intravenous Iron ◽  
Deficiency Anemia ◽  
Healthy Controls ◽  
Iron Treatment ◽  
Oxidant Status

Objective: This study aims to clarify the effects of intravenous iron supplementation on biomarkers for oxidative stress in women with iron deficiency anemia. Methods: This is a cross-sectional review of 40 healthy women and 40 women who underwent intravenous iron treatment due to anemia. Biochemical markers for oxidative stress were determined for both healthy controls and anemic patients. These markers were also evaluated at hour 1 and day 30 of intravenous iron treatment. Results: The patients with anemia had significantly higher catalase activity and total oxidant status (TOS) but significantly lower nitrate and total anti-oxidant status (TAS) than the healthy controls (p=0.0245, p<0.0001, p=0.0437 and p<0.0001 respectively). At hour 1 of intravenous iron treatment, nitrate, nitrite, nitric oxide, total thiol and TAS values were significantly lower and TOS values were significantly higher than those before the administration of treatment (p=0.0322, p=0.0003, p=0.0005, p<0.0001, p<0.0001 and p=0.004). At day 30 of intravenous iron treatment, catalase activity, nitrate, total thiol and TOS values were significantly lower than those before the administration of treatment (p=0.0332, p=0.0015, p=0.0391 and p<0.0001 respectively) and at hour 1 of treatment (p=0.0498, p<0.0001, p=0.0004 and p<0.0001 respectively). At day 30 of intravenous iron treatment, nitric oxide and TAS values were significantly higher than those before the administration of treatment (p=0.0480 and p=0.001 respectively) and at hour 1 of treatment (p<0.0001 for both). Conclusion: Intravenous iron replacement prompts oxidative stress at hour 1 of infusion in adults with anemia but this increase resolves partially in the following 30 days.

scholarly journals Catfish Oil (Pangasius hypophthalmus) effect to ferritin and sTfR in iron deficiency anemia

2021 ◽  
Vol 10 (1) ◽  
pp. 28-35
Author(s):  
Hersanti Sulistyaningrum ◽  
Fronthea Swastawati ◽  
Maria Mexitalia ◽  
Etika Ratna Noer
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Ferrous Sulfate ◽  
Wistar Rats ◽  
Heme Iron ◽  
Deficiency Anemia ◽  
Significant Difference ◽  
Before And After ◽  
Male Wistar Rats ◽  
Catfish Oil

Background: Iron deficiency anemia is a micronutrient problem and the prevalence is still high. Catfish oil (Pangasius hypophthalmus) is a natural source of heme iron which can improve body iron levels.Objectives: This study was aimed to examine and analyze the effect of catfish oil on ferritin and sTfR levels in male wistar rats with iron deficiency anemia models.Materials and Methods: This study was conducted on male wistar rats which were divided into groups C- (standard feed), C+ (standard feed but had the iron removed), X1 (standard feed without iron but was supplemented with catfish oil), X2 (standard feed without iron but was supplemented with ferrous sulfate) for 14 days. Ferritin and sTfR levels were measured before and after intervention using ELISA.Results: The study showed an increase ferritin levels in X1 (21.87 ng/ml ±0.76), X2 (24.47 ng/ml ±0.54) and there was no significant difference between the two (p=0.069; p>0.05); a decrease in C- (0.25 ng/ml ±0.43), C+ (0.32 ng/ml ±0.059) (p=0.00; p<0.05). The sTfR levels decreased before and after intervention (p=0.00; p<0.05) in C+ (0.24 μ/mL ±0.99), X1 (60.66 μ/mL ±0.29), X2 (62.10 μ/mL ±0.90) and increased in C- (0.40 μ/mL ±0.97).Conclusions: The study indicates ferritin levels increased in the rats receiving catfish oil is not different from the rats that received ferrous sulfate and sTfR levels decreased significantly in wistar rats with iron deficiency anemia receiving catfish oil although the results were not as good as ferrous sulfate supplementation

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