Predictors of remission to antidepressants in late-life depression: a systematic review

2018 ◽  
Vol 16 (2) ◽  
pp. 189-196
Author(s):  
Caroline Masse ◽  
Djamila Bennabi ◽  
Julie Giustiniani ◽  
Emmanuel Haffen ◽  
Daniel Sechter ◽  
...  
2018 ◽  
Author(s):  
Phoebe Chan ◽  
Sunil Bhar ◽  
Tanya E. Davison ◽  
Colleen Doyle ◽  
Bob G. Knight ◽  
...  

BACKGROUND The prevalence rates of depressive and anxiety disorders are high in residential aged care settings. Older adults in such settings might be prone to these disorders because of losses associated with transitioning to residential care, uncertainty about the future, as well as a decline in personal autonomy, health, and cognition. Cognitive behavioral therapy (CBT) is efficacious in treating late-life depression and anxiety. However, there remains a dearth of studies examining CBT in residential settings compared with community settings. Typically, older adults living in residential settings have higher care needs than those living in the community. To date, no systematic reviews have been conducted on the content and the delivery characteristics of CBT for older adults living in residential aged care settings. OBJECTIVE The objective of this paper is to describe the systematic review protocol on the characteristics of CBT for depression and/or anxiety for older adults living in residential aged care settings. METHODS This protocol was developed in compliance with the recommendations of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). Studies that fulfill the inclusion criteria will be identified by systematically searching relevant electronic databases, reference lists, and citation indexes. In addition, the PRISMA flowchart will be used to record the selection process. A pilot-tested data collection form will be used to extract and record data from the included studies. Two reviewers will be involved in screening the titles and abstracts of retrieved records, screening the full text of potentially relevant reports, and extracting data. Then, the delivery and content characteristics of different CBT programs of the included studies, where available, will be summarized in a table. Furthermore, the Downs and Black checklist will be used to assess the methodological quality of the included studies. RESULTS Systematic searches will commence in May 2018, and data extraction is expected to commence in July 2018. Data analyses and writing will happen in October 2018. CONCLUSIONS In this section, the limitations of the systematic review will be outlined. Clinical implications for treating late-life depression and/or anxiety, and implications for residential care facilities will be discussed. CLINICALTRIAL PROSPERO 42017080113; https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=80113 (Archived by WebCite at http://www.webcitation.org/70dV4Qf54) REGISTERED REPORT IDENTIFIER RR1-10.2196/9902


2016 ◽  
Vol 31 (9) ◽  
pp. 963-973 ◽  
Author(s):  
Sarah T. Stahl ◽  
Juleen Rodakowski ◽  
Ester M. Saghafi ◽  
Mijung Park ◽  
Charles F. Reynolds ◽  
...  

2016 ◽  
Vol 24 (7) ◽  
pp. 547-565 ◽  
Author(s):  
Sanjeev Kumar ◽  
Benoit H. Mulsant ◽  
Angela Y. Liu ◽  
Daniel M. Blumberger ◽  
Zafiris J. Daskalakis ◽  
...  

2017 ◽  
Vol 25 (3) ◽  
pp. S63-S64
Author(s):  
Kathleen Bingham ◽  
Sanjeev Kumar ◽  
Deirdre Dawson ◽  
Benoit H. Mulsant ◽  
Alastair J. Flint

2015 ◽  
Vol 11 (7S_Part_14) ◽  
pp. P655-P655
Author(s):  
Kenia Kelly Fiaux do Nascimento ◽  
Kelly Silva Pereira ◽  
Breno SatlerS. Diniz ◽  
Leandro F. Malloy-Diniz ◽  
Meryl Butters

2015 ◽  
Vol 69 ◽  
pp. 35-41 ◽  
Author(s):  
Kenia Kelly Fiaux do Nascimento ◽  
Kelly P. Silva ◽  
Leandro F. Malloy-Diniz ◽  
Meryl A. Butters ◽  
Breno S. Diniz

2022 ◽  
Vol 12 (1) ◽  
pp. 187-203
Author(s):  
Veronica Fernandez-Rodrigues ◽  
Yolanda Sanchez-Carro ◽  
Luisa Natalia Lagunas ◽  
Laura Alejandra Rico-Uribe ◽  
Andres Pemau ◽  
...  

2019 ◽  
Vol 33 (5) ◽  
pp. 289-303 ◽  
Author(s):  
Monique A. Pimontel ◽  
Dora Kanellopoulos ◽  
Faith M. Gunning

Objective: Apathy is a common phenomenon in late-life depression and is associated with poor outcomes. Apathy is often unrecognized in older depressed adults, and efficacious treatment options are lacking. This review provides a systematic review of the neuroanatomical abnormalities associated with apathy in late-life depression. In addition, the review summarizes the neuroimaging findings from studies of neurodegenerative and focal brain injury conditions that frequently present with apathy. The goal is to elucidate cerebral network abnormalities that give rise to apathy in older adults with mood disturbances and to inform future treatment targets. Method: Systematic literature review. Results: The few studies that have directly examined the neuroanatomical abnormalities of apathy in late-life depression suggest disturbances in the anterior cingulate cortex, insula, orbital and dorsal prefrontal cortex, striatum, and limbic structures (ie, amygdala, thalamus, and hippocampus). Studies examining the neuroanatomical correlates of apathy in other aging populations are consistent with the pattern observed in late-life depression. Conclusions: Apathy in late-life depression appears to be accompanied by neuroanatomical abnormalities in the salience and reward networks. These network findings are consistent with that observed in individuals presenting with apathy in other aging-related conditions. These findings may inform future treatments that target apathy.


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