Successful epilepsy surgery in frontal lobe epilepsy with startle seizures: a SEEG study

2015 ◽  
Vol 17 (4) ◽  
pp. 363-371 ◽  
Author(s):  
Ana Ciurea ◽  
Irina Popa ◽  
Mihai Dragos Maliia ◽  
Nagy Csilla-Johanna ◽  
Andrei Barborica ◽  
...  
2019 ◽  
Vol 121 ◽  
pp. e32-e38 ◽  
Author(s):  
Cuiping Xu ◽  
Tao Yu ◽  
Guojun Zhang ◽  
Yuping Wang ◽  
Yongjie Li

1997 ◽  
Vol 69 (1-4) ◽  
pp. 202-209 ◽  
Author(s):  
J.R. Smith ◽  
M.R. Lee ◽  
D.W. King ◽  
A.M. Murro ◽  
Y.D. Park ◽  
...  

Neurocase ◽  
2017 ◽  
Vol 23 (3-4) ◽  
pp. 239-248 ◽  
Author(s):  
Kirsten Labudda ◽  
Markus Mertens ◽  
Thilo Kalbhenn ◽  
Reinhard Schulz ◽  
Friedrich G Woermann

2019 ◽  
Vol 140 (4) ◽  
pp. 259-267 ◽  
Author(s):  
Joseph Samuel P ◽  
Ramshekhar N. Menon ◽  
Anuvitha Chandran ◽  
Sanjeev V. Thomas ◽  
George Vilanilam ◽  
...  

2012 ◽  
pp. 80-84
Author(s):  
Martine Gavaret ◽  
Jean-Michel Badier ◽  
Jean-Claude Peragut ◽  
Patrick Chauvel

2007 ◽  
Vol 7 (4) ◽  
pp. 98-99 ◽  
Author(s):  
John W. Miller

Surgical Outcome and Prognostic Factors of Frontal Lobe Epilepsy Surgery. Jeha LE, Najm I, Bingaman W, Dinner D, Widdess-Walsh P, Luders H. Brain 2007;130(Pt 2):574–584. Epub 2007 Jan 5. Frontal lobe epilepsy (FLE) surgery is the second most common surgery performed to treat pharmacoresistant epilepsy. Yet, little is known about long-term seizure outcome following frontal lobectomy. The aim of this study is to investigate the trends in longitudinal outcome and identify potential prognostic indicators in a cohort of FLE patients investigated using modern diagnostic techniques. We reviewed 70 patients who underwent a frontal lobectomy between 1995 and 2003 (mean follow-up 4.1 ± 3 years). Data were analysed using survival analysis and multivariate regression with Cox proportional hazard models. A favourable outcome was defined as complete seizure-freedom, allowing for auras and seizures restricted to the first post-operative week. The estimated probability of complete seizure-freedom was 55.7% [95% confidence interval (CI) = 50–62] at 1 post-operative year, 45.1% (95% CI = 39–51) at 3 years, and 30.1% (95% CI = 21–39) at 5 years. Eighty per cent of seizure recurrences occurred within the first 6 post-operative months. Late remissions and relapses occurred, but were rare. After multivariate analysis, the following variables retained their significance as independent predictors of seizure recurrence: MRI-negative malformation of cortical development as disease aetiology [risk ratio (RR) = 2.22, 95% CI = 1.40–3.47], any extrafrontal MRI abnormality (RR = 1.75, 95% CI = 1.12–2.69), generalized/non-localized ictal EEG patterns (RR = 1.83, 95% CI = 1.15–2.87), occurrence of acute post-operative seizures (RR = 2.17, 95% CI = 1.50–3.14) and incomplete surgical resection (RR = 2.56, 95% CI = 1.66–4.05) (log likelihood-ratio test P-value < 0.0001). More than half of patients in favourable prognostic categories were seizure-free at 3 years, and up to 40% were seizure-free at 5 years, compared to <15% in those with unfavourable outcome predictors. These data underscore the importance of appropriate selection of potential surgical candidates.


Epilepsia ◽  
2012 ◽  
Vol 53 (10) ◽  
pp. 1746-1755 ◽  
Author(s):  
Stefanie P. Lazow ◽  
Vijay M. Thadani ◽  
Karen L. Gilbert ◽  
Richard P. Morse ◽  
Krzysztof A. Bujarski ◽  
...  

Brain ◽  
2007 ◽  
Vol 130 (2) ◽  
pp. 574-584 ◽  
Author(s):  
L. E. Jeha ◽  
I. Najm ◽  
W. Bingaman ◽  
D. Dinner ◽  
P. Widdess-Walsh ◽  
...  

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