Emotional distress and health-related quality of life among cutaneous melanoma follow-up outpatients: the role of self-perception of body image and surgical scarring

2017 ◽  
Vol 27 (4) ◽  
pp. 435-438
Author(s):  
Stefania Bassino ◽  
Simone Ribero ◽  
Marco Miniotti ◽  
Angelo Picardi ◽  
Virginia Caliendo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Image ◽  
Emotional Distress ◽  
Cutaneous Melanoma ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Impact of recent life events on the health related quality of life of adolescents and youths: the role of gender and life events typologies in a follow-up study

2010 ◽  
Vol 8 (1) ◽  
pp. 71 ◽  
Author(s):  
Ester Villalonga-Olives ◽  
Sonia Rojas-Farreras ◽  
Gemma Vilagut ◽  
Jorge A Palacio-Vieira ◽  
José Valderas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Life Events ◽  
Health Related Quality ◽  
Follow Up Study ◽  
Related Quality ◽  
Health Related

scholarly journals Neurocognitive Function, Psychosocial Outcome, and Health-Related Quality of Life of the First-Generation Metastatic Melanoma Survivors Treated with Ipilimumab

2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Anne Rogiers ◽  
Christophe Leys ◽  
Justine Lauwyck ◽  
Adrian Schembri ◽  
Gil Awada ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Metastatic Melanoma ◽  
Emotional Distress ◽  
Neurocognitive Function ◽  
Psychosocial Outcome ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Purpose. To assess neurocognitive function (NCF), psychosocial outcome, health-related quality of life (HRQoL), and long-term effects of immune-related adverse events (irAE) on metastatic melanoma survivors treated with ipilimumab (IPI). Methods. Melanoma survivors were identified within two study populations (N=104), at a single-center university hospital, and defined as patients who were disease-free for at least 2 years after initiating IPI. Data were collected using 4 patient-reported outcome measures, computerized NCF testing, and a semistructured interview at the start and 1-year follow-up. Results. Out of 18 eligible survivors, 17 were recruited (5F/12M); median age is 57 years (range 33-86); and median time since initiating IPI was 5.6 years (range 2.1-9.3). The clinical interview revealed that survivors suffered from cancer-related emotional distress such as fear of recurrence (N=8), existential problems (N=2), survivor guilt (N=2), and posttraumatic stress disorder (N=6). The mean EORTC QLQ-C30 Global Score was not significantly different from the European mean of the healthy population. Nine survivors reported anxiety and/or depression (Hospitalization Depression Scale) during the survey. Seven survivors (41%) reported fatigue (Fatigue Severity Scale). Seven patients (41%) had impairment in NCF; only three out of seven survivors had impairment in subjective cognition (Cognitive Failure Questionnaire). Anxiety, depression, fatigue, and neurocognitive symptoms remained stable at the 1-year follow-up. All cases of skin toxicity (N=8), hepatitis (N=1), colitis (N=3), and sarcoidosis (N=1) resolved without impact on HRQoL. Three survivors experienced hypophysitis; all suffered from persistent fatigue and cognitive complaints 5 years after onset. One survivor who experienced a Guillain-Barré-like syndrome suffered from persisting depression, fatigue, and impairment in NCF. Conclusion. A majority of melanoma survivors treated with IPI continue to suffer from emotional distress and impairment in NCF. Timely detection in order to offer tailored care is imperative, with special attention for survivors with a history of neuroendocrine or neurological irAE. The trial is registered with B.U.N. 143201421920.

scholarly journals Health-related quality of life after pelvic organ prolapse surgery in Ethiopia: A 6 month follow-up study

2020 ◽  
Author(s):  
Tadesse Belayneh ◽  
Abebaw Gebeyehu ◽  
Mulat Adefris ◽  
Guri Rortveit ◽  
Janne Lillelid Gjerde ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Image ◽  
Surgical Treatment ◽  
Pelvic Organ Prolapse ◽  
Pelvic Organ ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Background Pelvic organ prolapse (POP) affects health-related quality of life (HRQoL). Patient-reported outcomes (PRO) measures the quality of care from the patient’s perspective. PROs are an important measure of surgical outcome and used to calculate health gains after surgical treatment. We assessed HRQoL in women undergoing surgical repair of POP. Methods Two hundred fifteen women with stage III or IV prolapse underwent surgical POP repair between February 2018 and May 2019. Pelvic Organ Prolapse Quality of Life (P-QoL-20) was administered at baseline, 3 and 6 months postoperatively to assess HRQoL. Depressive symptoms and body image also evaluated. Linear mixed-effect models were used to compare pre and postoperative HRQoL scores and investigate potential predictors. Results Participant’s mean age was 49.3 ± 9.4 years. Most (81.9%) had stage III prolapse and underwent a vaginal hysterectomy, although 40% preferred uterine preservation. No differences were seen between women follow-up and those lost to follow-up in HRQoL (p > 0.05). The P-QoL, depressive symptoms, and body image were improved 6 months post-operatively. The change in P-QoL significantly associated with body image scores. The type of surgery did not show a significant difference. Being married showed an improvement in the personal relationship subscale score (β = 5.8, p < 0.01). Conclusions Our results indicated a potential improvement of HRQoL after surgical treatment. The result could be useful for patient counseling on the expected HRQoL outcomes of surgical treatment. Surgical service should be accessible for women suffering from POP to improve HRQoL.

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