Angiomatoid lesions (leukocytoclastic vasculitis) as paraneoplastic manifestations of multiple myeloma IgA λ

2011 ◽  
Vol 21 (2) ◽  
pp. 260-261 ◽  
Author(s):  
Marta CARLESIMO ◽  
Alessandra NARCISI ◽  
Diego ORSINI ◽  
Pier Paolo DI RUSSO ◽  
Giorgia CORTESI ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Leukocytoclastic Vasculitis

scholarly journals Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma

2012 ◽  
Vol 29 (4) ◽  
pp. 397-400 ◽  
Author(s):  
Seckin Cagirgan ◽  
Nur Soyer ◽  
Filiz Vural ◽  
Guray Saydam ◽  
Ilgin Yildirim Simsir ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Leukocytoclastic Vasculitis ◽  
Pulmonary Calcinosis

scholarly journals Cryoglobulinemic leukocytoclastic vasculitis secondary to multiple myeloma

QJM ◽  
2009 ◽  
Vol 103 (8) ◽  
pp. 619-620
Author(s):  
S. Fritsch ◽  
A. P. Azambuja
Keyword(s):  
Multiple Myeloma ◽  
Leukocytoclastic Vasculitis

Development of leukocytoclastic vasculitis in a patient with multiple myeloma during treatment with thalidomide

2004 ◽  
Vol 83 (7) ◽  
pp. 467-470 ◽  
Author(s):  
Mathias Witzens ◽  
Thomas Moehler ◽  
Kai Neben ◽  
Stefan Fruehauf ◽  
Wolfgang Hartschuh ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Leukocytoclastic Vasculitis

scholarly journals Leukocytoclastic Vasculitis due to Thalidomide in Multiple Myeloma

2007 ◽  
Vol 37 (9) ◽  
pp. 704-707 ◽  
Author(s):  
N. D. Yildirim ◽  
M. Ayer ◽  
R. D. Kucukkaya ◽  
N. Alpay ◽  
O. Mete ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Leukocytoclastic Vasculitis

scholarly journals Leukocytoclastic vasculitis with eosinophilic infiltration associated with thalidomide therapy for multiple myeloma: A case report

2017 ◽  
Vol 66 (3) ◽  
pp. 497-498 ◽  
Author(s):  
Susumu Ichiyama ◽  
Yoko Funasaka ◽  
Hiroko Yamashita ◽  
Hideto Tamura ◽  
Koiti Inokuchi ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Case Report ◽  
Leukocytoclastic Vasculitis ◽  
Eosinophilic Infiltration

Paraneoplastic Cutaneous Leukocytoclastic Vasculitis Disclosing Multiple Myeloma: A Case Report

2011 ◽  
Vol 11 (4) ◽  
pp. 373-374 ◽  
Author(s):  
Pierre Peterlin ◽  
Thierry Ponge ◽  
Nicolas Blin ◽  
Philippe Moreau ◽  
Mohamed Hamidou ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Case Report ◽  
Leukocytoclastic Vasculitis

Successful management of cryoglobulinemia-induced leukocytoclastic vasculitis with thalidomide in a patient with multiple myeloma

2005 ◽  
Vol 84 (9) ◽  
pp. 609-613 ◽  
Author(s):  
M. Cem Ar ◽  
Teoman Soysal ◽  
Gulen Hatemi ◽  
Ayse Salihoglu ◽  
Hasan Yazici ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Leukocytoclastic Vasculitis ◽  
Successful Management

Proteasome inhibitors as therapeutics

2005 ◽  
Vol 41 ◽  
pp. 205-218
Author(s):  
Constantine S. Mitsiades ◽  
Nicholas Mitsiades ◽  
Teru Hideshima ◽  
Paul G. Richardson ◽  
Kenneth C. Anderson
Keyword(s):  
Multiple Myeloma ◽  
Drug Class ◽  
Proteasome Inhibitors ◽  
Cell Cycle Regulators ◽  
Current State ◽  
Intracellular Mechanism ◽  
Ubiquitin Proteasome ◽  
Proteasome Pathway ◽  
Hodgkin's Lymphomas ◽  
Clinical Research Data

The ubiquitin–proteasome pathway is a principle intracellular mechanism for controlled protein degradation and has recently emerged as an attractive target for anticancer therapies, because of the pleiotropic cell-cycle regulators and modulators of apoptosis that are controlled by proteasome function. In this chapter, we review the current state of the field of proteasome inhibitors and their prototypic member, bortezomib, which was recently approved by the U.S. Food and Drug Administration for the treatment of advanced multiple myeloma. Particular emphasis is placed on the pre-clinical research data that became the basis for eventual clinical applications of proteasome inhibitors, an overview of the clinical development of this exciting drug class in multiple myeloma, and a appraisal of possible uses in other haematological malignancies, such non-Hodgkin's lymphomas.

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