Effects of oral vitamin D3 supplementation in stage 3 chronic kidney disease subjects: insulin resistance syndrome and hormonal disturb interactions

2018 ◽  
Vol 76 (3) ◽  
pp. 313-325 ◽  
Author(s):  
Amina Tahar ◽  
Faiza Zerdoumi ◽  
Messaoud Saidani ◽  
Lakhdar Griene ◽  
Elhadj-Ahmed Koceir
Keyword(s):  
Insulin Resistance ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Vitamin D3 ◽  
Insulin Resistance Syndrome ◽  
Oral Vitamin ◽  
Vitamin D3 Supplementation

32: Effect of Vitamin D3 Supplementation on Bone Mineral Density in Chronic Kidney Disease

2008 ◽  
Vol 51 (4) ◽  
pp. B35
Author(s):  
Cortney Bosworth ◽  
Laura Kooienga ◽  
Jessica Kendrick ◽  
Gerard Smits ◽  
Michel Chonchol
Keyword(s):  
Bone Mineral Density ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Bone Mineral ◽  
Vitamin D3 ◽  
Mineral Density ◽  
Vitamin D3 Supplementation

scholarly journals MP015THE EFFECT OF VITAMIN D3 SUPPLEMENTATION ON P2X7 RECEPTOR FUNCTION IN EARLY STAGES OF CHRONIC KIDNEY DISEASE

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i347-i348 ◽  
Author(s):  
Ingrid Lajdova ◽  
Viera Spustova ◽  
Adrian Oksa ◽  
Dusan Chorvat ◽  
Alzbeta Marcek Chorvatova
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Vitamin D3 ◽  
P2x7 Receptor ◽  
Receptor Function ◽  
Early Stages ◽  
Vitamin D3 Supplementation

scholarly journals The Effect of Vitamin D3 Supplementation on Intracellular Calcium and Plasma Membrane Calcium ATPase Activity in Early Stages of Chronic Kidney Disease

2014 ◽  
pp. S593-S599
Author(s):  
M. MORVOVÁ ◽  
I. LAJDOVÁ ◽  
V. SPUSTOVÁ ◽  
M. ZVARÍK ◽  
L. ŠIKUROVÁ
Keyword(s):  
Chronic Kidney Disease ◽  
Plasma Membrane ◽  
Kidney Disease ◽  
Healthy Volunteers ◽  
Intracellular Calcium ◽  
Vitamin D3 ◽  
Calcium Atpase ◽  
Plasma Membrane Calcium Atpase ◽  
Vitamin D3 Supplementation ◽  
The Impact

Chronic kidney disease (CKD) is associated with increased concentration of intracellular calcium, which is pathological and may lead to irreversible damage of cell functions and structures. The aim of our study was to investigate the impact of 6 months vitamin D3 supplementation (14 000 IU/week) on free cytosolic calcium concentration ([Ca2+]i) and on the plasma membrane calcium ATPase (PMCA) activity of patients with CKD stage 2-3. PMCA activity of patients was also compared to that of healthy volunteers. Vitamin D3 supplementation of CKD patients resulted in the decrease of [Ca2+]i (119.79±5.87 nmol/l vs. 105.36±3.59 nmol/l, n=14, P<0.001), whereas PMCA activity of CKD patients (38.75±22.89 nmol Pi/mg/h) remained unchanged after vitamin D3 supplementation (40.96±17.74 nmol Pi/mg/h, n=14). PMCA activity of early stage CKD patients before supplementation of vitamin D3, was reduced by 34 % (42.01±20.64 nmol Pi/mg/h) in comparison to healthy volunteers (63.68±20.32 nmol Pi/mg/h, n=28, P<0.001). These results indicate that vitamin D3 supplementation had a lowering effect on [Ca2+]i and negligible effect on PMCA activity in CKD patients.

scholarly journals FP305EFFECTS OF VITAMIN D3 SUPPLEMENTATION ON THE URINARY EXPRESSION OF PODOCYTE-ASSOCIATED MRNA IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPOVITAMINOSIS D

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii169-iii169
Author(s):  
Francisco V Veronese ◽  
João T Timm ◽  
Cristina Karohl ◽  
Mariane dos Santos ◽  
Sane V Pereira ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Vitamin D3 ◽  
Hypovitaminosis D ◽  
Vitamin D3 Supplementation
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