scholarly journals Rate of change of end-stage renal disease treatment incidence 1978-1987--has there been selection?

1992 ◽  
Vol 2 (10) ◽  
pp. 1502-1506
Author(s):  
S J Rosansky ◽  
K Jackson

End-stage renal disease (ESRD) treatment rates in the United States have increased steadily since 1973. Decreasing selection against elderly patients with a poor prognostic primary cause of ESRD (i.e., diabetic nephropathy) may partly account for this increase in rates. To test this hypothesis, we calculated log ESRD treatment incidence (ESRDI) rates by four major primary causes of ESRD (diabetic nephropathy (DN), hypertensive nephropathy (HN), glomerulonephritis (GN), and cystic kidney disease (PC); two age groups (old (O), greater than 65 and young (Y), 15 to 44 yr of age) for black and white, male and female, new ESRD patients from 1978 to 1987. As predicted, summary log ESRDI slopes (produced by analysis of covariance) occurred in the following decreasing order, ODN (0.19), OGN = OHN = YDN (0.134). YHN = YPC = YGN (in white patients) = slope not significantly different from 0. Log ESRDI slopes for young black males and females with GN increased significantly between 1978 and 1987, possibly as a result of an increased incidence of GN. In conclusion, decreasing selection may be a factor in the continuing increase in the U.S. ESRD population.

KYAMC Journal ◽  
2013 ◽  
Vol 2 (2) ◽  
pp. 182-186
Author(s):  
ST Ahmed ◽  
MA Rahim ◽  
Z Ali ◽  
MM Iqbal

Background: Chronic Kidney Disease (CKD) is the third most common non-communicable disease throughout the world. Studies have shown that kidney patients suffer much from hypertension, diabetes than glomerulonephritis. Many of these CKD patients ultimately terminate to End Stage Renal Disease (ESRD) when life is not sustainable unless hemodialysis is initiated. Aim: The aim of this study was to identify primary renal disease leading to ESRD requiring hemodialysis and associated co-morbidities. Material and methods: Data was collected purposively from selected six hemodialysis centers. Patients were selected purposively who were available at the time of interview. Data was collected on working days at three shifts After taking informed consent from patients the pre-tested questionnaire was filled up by taking general history, family history, socioeconomic condition, drug history and available records were reviewed for collecting previous biochemical parameters. All entered data were analyzed by using SPSS program version 13.0. Result: Among total 393 subjects, male was 247(63%) and female 146 (37%). Majority were middle aged. Glomerulonephritis were found to be the leading cause of End Stage Renal Disease (ESRD) (50.4%), followed by diabetes in 31.1%, Poly Cystic Kidney Disease (PKD) 5.3%, Renal Stone in 3.7% and rest other. Among the study population hypertension was the most common co morbidity disease (63%) followed by ischemic heart disease and Cerebrovascular accidents. Conclusion: Glomerulonephritis was found to be the leading cause of End Stage Renal Disease (ESRD) and diabetic nephropathy was the second common cause. Hypertension was the most common associated co morbid disease. To evaluate the actual disease pattern a large scale study is required to find the outcome of haemodialysis patients.DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13262KYAMC Journal Vol.2(2) January 2012, 182-186


Author(s):  
Fuad Abdullah Dhaidan

Background: Chronic Kidney Disease (CKD) is the third most common non-communicable disease throughout the world. Most of the patients with chronic kidney disease suffer from hypertension, diabetes and with glomerulonephritis. Many of these CKD patients ultimately terminate to End Stage Renal Disease (ESRD) when life is not sustainable unless hemodialysis is initiated. This study was to identify systemic and renal disease leading to ESRD requiring hemodialysis and associated co-morbidities.Methods: Data was collected from three selected three hemodialysis centers in three hospitals during one-year study in Iraq. Patients were selected purposively who were available at the time of interview. Data was collected on working days at three shifts. these data collected from patients and their relatives in these centers after taking informed consent from patients the pre-tested questionnaire was filled up by taking general history, family history, socioeconomic condition, drug history and available records were reviewed for collecting previous biochemical parameters. All entered data were analyzed by using SPSS program.Results: Among total 400 subjects, male was 260 (65%) and female 140 (35%). Majority of patients were middle aged. Glomerulonephritis were found to be the leading cause of End Stage Renal Disease (ESRD) (50.4%), followed by diabetes in 31.1%, Poly Cystic Kidney Disease (PKD) 5.3%, Renal Stone in 3.7% and rest other. Among the study population hypertension was the most common co morbidity disease (63%) followed by ischemic heart disease and Cerebrovascular accidents.Conclusions: The leading cause of End Stage Renal Disease (ESRD) was the glomerulonephritis and diabetic nephropathy was the second common cause. Hypertension was the most common associated co morbid disease.


2004 ◽  
Vol 17 (1) ◽  
pp. 75-79 ◽  
Author(s):  
Kenyetta N. Nesbitt

Diabetic nephropathy is a complication of type 1 and type diabetes mellitus and the leading cause of end-stage renal disease in the United States. The health care system spends billions of dollars every year to treat end-stage renal disease patients. Health care providers must address diabetic nephropathy. The American Diabetes Association set forth recommendations for early detection to slow the progression of renal disease and treatment guidelines for patients with diabetes along with hypertension and diabetic nephropathy. Routine screening and treatment are the key to ending the trend of patients with diabetic nephropathy progressing to end-stage renal disease. Glycemic and blood pressure control is important for managing diabetic nephropathy. Angiotensinconverting enzyme inhibitors and angiotensin receptor blockers have become drugs of choice for treating diabetic nephropathy, based on clinical studies showing they slow the progression of renal disease. Whether protein restrictions are necessary in patients with diabetic nephropathy is being debated.


2014 ◽  
Vol 39 (1) ◽  
pp. 50-58 ◽  
Author(s):  
Laura C. Plantinga ◽  
Min Kim ◽  
Margarethe Goetz ◽  
David G. Kleinbaum ◽  
William McClellan ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document