Response to Letter on Curvature in the Dose Response of the Life Span Study Cancer Mortality Data by Linda Walshet al

2005 ◽  
Vol 163 (4) ◽  
pp. 478-478 ◽  
Author(s):  
Dale L. Preston ◽  
Donald A. Pierce ◽  
Yukiko Shimizu
Keyword(s):  
Life Span ◽  
Dose Response ◽  
Cancer Mortality ◽  
Mortality Data ◽  
Life Span Study

scholarly journals Vegetables and fruit intake and cancer mortality in the Hiroshima/Nagasaki Life Span Study

2003 ◽  
Vol 88 (5) ◽  
pp. 689-694 ◽  
Author(s):  
C Sauvaget ◽  
J Nagano ◽  
M Hayashi ◽  
E Spencer ◽  
Y Shimizu ◽  
...  
Keyword(s):  
Life Span ◽  
Cancer Mortality ◽  
Fruit Intake ◽  
Life Span Study

Tumorigenesis in High-Dose Total Body Irradiated Rhesus Monkeys--A Life Span Study

2003 ◽  
Vol 31 (2) ◽  
pp. 209-213 ◽  
Author(s):  
Carel F. Hollander ◽  
Chris Zurcher ◽  
Johan J. Broerse
Keyword(s):  
Life Span ◽  
Rhesus Monkeys ◽  
High Dose ◽  
Life Span Study ◽  
Total Body

scholarly journals Refining tree size and dose-response functions for control of invasive Pinus contorta

2021 ◽  
pp. 1-36
Author(s):  
Carol A. Rolando ◽  
Brian Richardson ◽  
Thomas S.H. Paul ◽  
Chanatda Somchit
Keyword(s):  
Dose Response ◽  
Pinus Contorta ◽  
Tree Size ◽  
Volume Index ◽  
Mortality Data ◽  
Field Calculation ◽  
Crown Area ◽  
Crown Diameter ◽  
Crown Volume ◽  
Canopy Area

Abstract Exotic conifers are rapidly spreading in many regions of New Zealand, as well as in many other countries, with detrimental impacts on both natural ecosystems and some productive sector environments. Herbicides, in particular the active ingredient (a.i.) triclopyr, are an important tool to manage invasive conifers, yet there is a paucity of information that quantifies the amount of herbicide required to kill trees of different sizes when applied as a basal bark treatment. Two sequential experiments were conducted to define the amount of triclopyr required to kill individual invasive Pinus contorta trees of different sizes when applied in a methylated seed oil to bark (either the whole stem or base of the tree) and to determine which tree size variates (height (HT), diameter at breast height (DBH), crown diameter (CD)), or derived attributes (crown area, crown volume index) best characterised this dose-response relationship. The outcomes of the dose-response research were compared to field operations where triclopyr was applied to the bark of trees from an aerial platform. Applying the herbicide to the whole stem, as opposed to the base of the tree only, significantly increased treatment efficacy. The tree size variates DBH, CD, crown area and crown volume index all provided good fits to the tree mortality data, with >91% prediction accuracy. Of these variates, crown diameter provided the most practical measure of tree size for ease of in-field calculation of dose by an operator. Herbicide rates used in field operations were 7 to 8 times higher than lethal doses calculated from experimental data. Our results highlight the potential for substantial reductions in herbicide rates for exotic conifer control, especially if dose-response data are combined with remotely sensed quantitative measurements of canopy area or volume using new precision technologies such as unmanned aerial vehicles.

scholarly journals Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century

2010 ◽  
Vol 28 (15) ◽  
pp. 2625-2634 ◽  
Author(s):  
Malcolm A. Smith ◽  
Nita L. Seibel ◽  
Sean F. Altekruse ◽  
Lynn A.G. Ries ◽  
Danielle L. Melbert ◽  
...  
Keyword(s):  
United States ◽  
Childhood Cancer ◽  
Cancer Mortality ◽  
Lymphoblastic Leukemia ◽  
The United States ◽  
Mortality Rates ◽  
Mortality Data ◽  
Childhood Cancers ◽  
Essential Information ◽  
The Impact

Purpose This report provides an overview of current childhood cancer statistics to facilitate analysis of the impact of past research discoveries on outcome and provide essential information for prioritizing future research directions. Methods Incidence and survival data for childhood cancers came from the Surveillance, Epidemiology, and End Results 9 (SEER 9) registries, and mortality data were based on deaths in the United States that were reported by states to the Centers for Disease Control and Prevention by underlying cause. Results Childhood cancer incidence rates increased significantly from 1975 through 2006, with increasing rates for acute lymphoblastic leukemia being most notable. Childhood cancer mortality rates declined by more than 50% between 1975 and 2006. For leukemias and lymphomas, significantly decreasing mortality rates were observed throughout the 32-year period, though the rate of decline slowed somewhat after 1998. For remaining childhood cancers, significantly decreasing mortality rates were observed from 1975 to 1996, with stable rates from 1996 through 2006. Increased survival rates were observed for all categories of childhood cancers studied, with the extent and temporal pace of the increases varying by diagnosis. Conclusion When 1975 age-specific death rates for children are used as a baseline, approximately 38,000 childhood malignant cancer deaths were averted in the United States from 1975 through 2006 as a result of more effective treatments identified and applied during this period. Continued success in reducing childhood cancer mortality will require new treatment paradigms building on an increased understanding of the molecular processes that promote growth and survival of specific childhood cancers.

Spontaneous neoplasms of the seminal vesicles in aged Han:Chin hamsters (Cricetulus criseus)

1988 ◽  
Vol 22 (2) ◽  
pp. 127-130 ◽  
Author(s):  
J. Kaspareit-Rittinghausen ◽  
F. Deerberg
Keyword(s):  
Life Span ◽  
Seminal Vesicles ◽  
Natural Death ◽  
Life Span Study ◽  
Histopathological Features

Tumours of the seminal vesicles were found in 11 of 182 male Han:Chin hamsters kept in a life-span study from weaning to their natural death. Histologically they were classified as adenocarcinoma ( n = 10) and hemangiosarcoma ( n = 1). The histopathological features of the neoplasms are described.

scholarly journals Application of Dynamic Poisson Models to Japanese Cancer Mortality Data

2008 ◽  
Vol 7 (2) ◽  
pp. 577-587
Author(s):  
Shuichi Midorikawa ◽  
Etsuo Miyaoka ◽  
Bruce Smith
Keyword(s):  
Cancer Mortality ◽  
Mortality Data ◽  
Poisson Models
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