Site-Specific Cancer Incidence and Mortality after Cerebral Angiography with Radioactive Thorotrast

2003 ◽  
Vol 160 (6) ◽  
pp. 691-706 ◽  
Author(s):  
Lois B. Travis ◽  
Michael Hauptmann ◽  
Linda Knudson Gaul ◽  
Hans H. Storm ◽  
Marlene B. Goldman ◽  
...  
Keyword(s):  
Cancer Incidence ◽  
Cerebral Angiography ◽  
Site Specific ◽  
Incidence And Mortality ◽  
Specific Cancer

Dietary patterns with combined and site-specific cancer incidence in Alberta’s Tomorrow Project cohort

2021 ◽  
Author(s):  
Romy F. Willemsen ◽  
Jessica McNeil ◽  
Emily Heer ◽  
Steven T. Johnson ◽  
Christine M. Friedenreich ◽  
...  
Keyword(s):  
Cancer Incidence ◽  
Dietary Patterns ◽  
Site Specific ◽  
Specific Cancer

scholarly journals Discrepancies between Canadian cancer research funding and site-specific cancer burden: a spotlight on ten disease sites

2018 ◽  
Vol 25 (5) ◽  
Author(s):  
A. C. Coronado ◽  
C. Finley ◽  
K. Badovinac ◽  
J. Han ◽  
J. Niu ◽  
...  
Keyword(s):  
Cancer Research ◽  
Research Funding ◽  
Information Management System ◽  
Site Specific ◽  
Cancer Burden ◽  
Specific Research ◽  
Research Survey ◽  
Research Investment ◽  
Incidence And Mortality ◽  
Specific Cancer

BackgroundCancer research is essential in evaluating the safety and effectiveness of emerging cancer treatments, which in turn can lead to ground-breaking advancements in cancer care. Given limited research funding, allocating resources in alignment with societal burden is essential. However, evidence shows that such alignment does not typically occur. The objective of the present study was to provide an updated overview of site-specific cancer research investment in Canada and to explore potential discrepancies between the site-specific burden and the level of research investment.MethodsThe 10 cancer sites with the highest mortality in 2015—which included brain, female breast, colorectal, leukemia, lung, non-Hodgkin lymphoma, ovary, pancreas, prostate, and uterus—were selected for the analysis. Information about site-specific research investment and cancer burden (raw incidence and mortality) was obtained from the Canadian Cancer Research Survey and Statistics Canada’s cansim (the Canadian Socio-Economic Information Management System) respectively. The ratio of site-specific research investment to site-specific burden was used as an indicator of overfunding (ratio > 1) or underfunding (ratio < 1).ResultsThe 3 cancer sites with the highest research investments were leukemia, prostate, and breast, which together represented 51.3% of 2015 cancer research funding. Conversely, the 3 cancer sites with the lowest investments were uterus, pancreas, and ovary, which together represented 7.8% of 2015 research funding. Relative to site-specific cancer burden, the lung, uterus, and colorectal sites were consistently the most underfunded.ConclusionsObserved discrepancies between cancer burden and research investment indicate that some cancer sites (such as lung, colorectal, and uterus) seem to be underfunded when site-specific incidence and mortality are taken into consideration.

scholarly journals Albuminuria, Kidney Function, and Cancer Risk in the Community

2020 ◽  
Vol 189 (9) ◽  
pp. 942-950
Author(s):  
Yejin Mok ◽  
Shoshana H Ballew ◽  
Yingying Sang ◽  
Josef Coresh ◽  
Corinne E Joshu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Kidney Disease ◽  
Cancer Risk ◽  
Cancer Incidence ◽  
Prostate Cancer Screening ◽  
Sensitivity Analyses ◽  
Site Specific ◽  
Specific Cancer ◽  
Shared Risk

Abstract Few studies have comprehensively investigated the association of 2 key kidney disease measures, estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (ACR), with cancer incidence. In 8,935 participants at the baseline (1996–1998) from the Atherosclerosis Risk in Communities study, we quantified the associations of eGFR (based on creatinine and cystatin C) and ACR with cancer risk using Cox regression models adjusted for potential confounders. Due to changing guidelines for prostate cancer screening during the follow-up period, we investigated overall cancer, overall nonprostate cancer, and site-specific cancer. During a median follow-up of 14.7 years, 2,030 incident cancer cases occurred. In demographically adjusted models, low eGFR and high ACR were associated with cancer incidence (both overall and overall nonprostate cancer). These associations were attenuated after adjusting for other shared risk factors, with a significant association remaining only for ACR (≥103 compared with 5 mg/g) and overall nonprostate cancer. For site-specific cancer, only high ACR showed a significant association with lung and urinary tract cancers. Of these, the association between ACR and lung cancer appeared most robust in several sensitivity analyses. Kidney disease measures, particularly high ACR, were independently associated with cancer risk. The association between ACR and lung cancer was uniquely robust, warranting future studies to explore potential mechanisms.

scholarly journals Socioeconomic status and site-specific cancer incidence, a Bayesian approach in a French Cancer Registries Network study

2018 ◽  
Vol 27 (4) ◽  
pp. 391-398 ◽  
Author(s):  
Joséphine Bryere ◽  
Olivier Dejardin ◽  
Ludivine Launay ◽  
Marc Colonna ◽  
Pascale Grosclaude ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Bayesian Approach ◽  
Cancer Incidence ◽  
Cancer Registries ◽  
Site Specific ◽  
Specific Cancer

scholarly journals Cancer Incidence and Mortality in the Oldest Old: a Nationwide Study in Finland

2020 ◽  
Author(s):  
Tomas Tanskanen ◽  
Karri J M Seppä ◽  
Anni Virtanen ◽  
Nea K Malila ◽  
Janne M Pitkäniemi
Keyword(s):  
Cancer Incidence ◽  
Excess Mortality ◽  
Oldest Old ◽  
Cancer Registries ◽  
Age Group ◽  
Incidence And Mortality ◽  
Specific Cancer ◽  
Specific Mortality ◽  
Cancer Specific Mortality ◽  
Related Mortality

Abstract The world’s population is aging rapidly. This study reports the burden of cancer in the oldest old (≥85 years) in Finland in 1953-2017 and estimates age-specific cancer rates in the old population (65-99 years) in 1988-2017. The Finnish Cancer Registry provided data on all cancer diagnoses, cancer deaths and other deaths in cancer patients in Finland in 1953-2017. Between 1953-1957 and 2013-2017, the proportion of incident cancers in those aged ≥85 years increased from 1.5% to 9.6% (597 to 15,360 new cases), and in 2013-2017, more new cancers were diagnosed at age ≥85 years than age &lt;50 years. Cancer incidence and excess mortality attributable to cancer peaked at age 85-94 years and declined subsequently, whereas cancer-specific mortality continued to increase or plateaued. Due to demographic changes, the number of new cancers in the oldest old has increased substantially in Finland, and currently, nearly one in 10 cancers are diagnosed in this age group. The increasing cancer burden in the oldest old poses a major challenge for healthcare and needs to be addressed in designing clinical research and reporting of cancer registries. In old populations with competing risks of death, we propose excess cancer mortality as a measure of cancer-related mortality.

scholarly journals Kreft og dødelighet blant norske feiere: Vurdering av datakvalitet

2009 ◽  
Vol 11 (2) ◽  
Author(s):  
Bjørn Møller ◽  
Aage Andersen
Keyword(s):  
Mortality Rate ◽  
Cancer Incidence ◽  
English Summary ◽  
Font Size ◽  
Local Authorities ◽  
Incidence And Mortality ◽  
Specific Cancer ◽  
Total Cancer ◽  
Standardized Mortality Rate

<strong><span style="font-family: TimesNewRomanPS-BoldMT;"><font face="TimesNewRomanPS-BoldMT"><p align="left"> </p></font></span><p align="left"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">ENGLISH SUMMARY</span></span></p></strong><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><font face="TimesNewRomanPSMT" size="2"><font face="TimesNewRomanPSMT" size="2"><p align="left">Møller B, Andersen Aa.</p></font></font></span><font face="TimesNewRomanPSMT" size="2"><p align="left"> </p></font></span><p align="left"><strong><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">Cancer and mortality among Norwegian chimney sweeps.</span></span></strong><em><span style="font-size: x-small; font-family: TimesNewRomanPS-ItalicMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-ItalicMT;"><em><font face="TimesNewRomanPS-ItalicMT" size="2"><font face="TimesNewRomanPS-ItalicMT" size="2"><p align="left">Nor J Epidemiol</p></font></font></em></span><em><font face="TimesNewRomanPS-ItalicMT" size="2"><p align="left"> </p></font></em></span><p align="left"> </p></em><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;">2001; </span></span><strong><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">11 </span></span></strong><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;">(2): 193-196.<p align="left">The aim of the study was to investigate cancer incidence and mortality among Norwegian chimney</p><p align="left">sweeps. A cohort of 1483 persons was established by collecting information about current and former</p><p align="left">chimney sweeps from all the local authorities. Information from housing censuses (HS) in 1960, 1970</p><p align="left">and 1980 were used to study the quality of the data. This revealed that the mortality among those chimney</p><p align="left">sweeps in HS that are included in our cohort is lower than the mortality among those not reported</p><p align="left">to us from the local authorities. Because of this, only a sub-cohort of 287 chimney sweeps from the</p><p align="left">largest cities were considered reliable. The uncertainty concerning risks for the different cancer sites in</p><p align="left">this group is large, since calculations are based on very few cases. The standardized incidence rate</p><p align="left">(SIR) for total cancer is 1.3 (95% CI: 1.0–1.8), and the standardized mortality rate (SMR) for all deaths</p><p align="left">is 1.2 (95% CI: 1.0–1.4). We also analyzed the 1292 persons who stated chimney sweep as occupation</p><p align="left">in the housing censuses in 1960, 1970 or 1980. SIR and SMR analyses in this group show no increased</p><p>risk for any specific cancer sites, nor for any cause specific death.</p></span></span></p>

scholarly journals The relationship between area poverty rate and site‐specific cancer incidence in the United States

Cancer ◽  
2014 ◽  
Vol 120 (14) ◽  
pp. 2191-2198 ◽  
Author(s):  
Francis P. Boscoe ◽  
Christopher J. Johnson ◽  
Recinda L. Sherman ◽  
David G. Stinchcomb ◽  
Ge Lin ◽  
...  
Keyword(s):  
United States ◽  
Cancer Incidence ◽  
The United States ◽  
Poverty Rate ◽  
Site Specific ◽  
Specific Cancer ◽  
The Relationship

scholarly journals Thyroid dysfunction and cancer incidence: a systematic review and meta-analysis

2020 ◽  
Vol 27 (4) ◽  
pp. 245-259 ◽  
Author(s):  
Thi-Van-Trinh Tran ◽  
Cari M Kitahara ◽  
Florent de Vathaire ◽  
Marie-Christine Boutron-Ruault ◽  
Neige Journy
Keyword(s):  
Systematic Review ◽  
Risk Ratio ◽  
Cancer Incidence ◽  
Thyroid Dysfunction ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Cancer Site ◽  
Site Specific ◽  
Random Effects Models ◽  
Specific Cancer

In this study, we aimed to evaluate site-specific cancer risks associated with hyperthyroidism or hypothyroidism. We performed a systematic review of observational studies reporting associations between hyperthyroidism or hypothyroidism and subsequent site-specific cancer incidence, in MEDLINE and the COCHRANE library (inception-28/01/2019) (PROSPERO: CRD42019125094). We excluded studies with thyroid dysfunction evaluated as a cancer biomarker or after prior cancer diagnosis and those considering transient thyroid dysfunction during pregnancy or severe illnesses. Risk of bias was assessed using a modified Newcastle–Ottawa scale. Risk estimates were pooled using random-effects models when ≥5 studies reported data for a specific cancer site. Twenty studies were included, of which 15 contributed to the meta-analysis. Compared to euthyroidism, hyperthyroidism was associated with higher risks of thyroid (pooled risk ratio: 4.49, 95%CI: 2.84–7.12), breast (pooled risk ratio: 1.20, 95%CI: 1.04–1.38), and prostate (pooled risk ratio: 1.35, 95%CI: 1.05–1.74), but not respiratory tract (pooled risk ratio: 1.06, 95%CI: 0.80–1.42) cancers. Hypothyroidism was associated with a higher risk of thyroid cancer within the first 10 years of follow-up only (pooled risk ratio: 3.31, 95%CI: 1.20–9.13). There was no or limited evidence of thyroid dysfunction-related risks of other cancer sites. In conclusion, thyroid dysfunction was associated with increased risks of thyroid, breast, and prostate cancers. However, it remains unclear whether these findings represent causal relationships because information on treatments and potential confounders was frequently lacking.

scholarly journals Body weight variability and cancer incidence in men aged 40 years and older-Korean National Insurance Service Cohort

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yu Jin Cho ◽  
Jin Seul Kawk ◽  
Hyung-Jin Yoon ◽  
Minseon Park
Keyword(s):  
Prostate Cancer ◽  
Body Weight ◽  
Risk Factor ◽  
Kidney Cancer ◽  
Cancer Incidence ◽  
Absolute Difference ◽  
Site Specific ◽  
Specific Cancer ◽  
Risk Of Cancer ◽  
The Impact

AbstractRepeated weight fluctuation has been proposed as a potential risk factor for increasing morbidity and mortality including cancer. We aimed to investigate the association between body weight variability (BWV) and all cancer and site-specific cancer incidence and the impact of smoking on these associations. A total of 1,759,848 cancer-free male subjects who had their weight measured at least 5 times from the National Health Insurance Service-Health Screening Cohort from 2002 to 2011 were included and followed up until 2015. BWV was defined as the average absolute difference between successive values (ASV). The risk of cancer and site-specific cancer from BWV was identified using Cox proportional hazards regression analysis using hazard ratios (HRs) and 95% confidence intervals (CIs) adjusted for potential confounders including weight, and stratified analysis was also conducted according to smoking status. During the 7,015,413 person-years of follow-up, 11,494 patients (0.65%) developed new-onset cancers. BWV was associated with a higher risk of all cancers after adjustment for confounders. The highest BWV quintile group compared to the lowest had greater risks of all cancers and site-specific cancers including lung, liver, and prostate cancer (HR 1.22, 95% CI 1.15–1.30; HR 1.22, 95% CI 1.07–1.39; HR 1.46, 95% CI 1.19–1.81; HR 1.36, 95% CI 1.15–1.62, in all cancers, lung, liver and prostate cancer, respectively). Due to small number of cancer occurrence, the risk of kidney cancer was increased, but statistically insignificant (HR 1.38, 95% CI 0.91–2.10). Similar results were observed in noncurrent smokers. However, in current smokers, the risks of all cancers and only prostate cancer were significantly increased in the highest BWV quintile group (HR 1.19, 95% CI 1.09–1.31; HR 1.51, 95% CI 1.08–2.11). The risk of kidney cancer also increased in this group, although the finding was not statistically significant (HR 1.77, 95% CI 0.87–3.63) This study suggested BWV is an independent risk factor for cancer in men, especially in lung, liver, and prostate cancer, but evidence was weaker in kidney cancer. This association remained significant only in prostate cancer in current smokers.

Understanding Population-Based Site-Specific Cancer Incidence Rates in the USA

2011 ◽  
Vol 27 (2) ◽  
pp. 263-268 ◽  
Author(s):  
Ray M. Merrill ◽  
Arielle Sloan ◽  
Lelinneth B. Novilla
Keyword(s):  
Cancer Incidence ◽  
Population Based ◽  
Incidence Rates ◽  
Site Specific ◽  
Specific Cancer ◽  
The Usa ◽  
Cancer Incidence Rates
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