Interaction between Radioadaptive Response and Radiation-Induced Bystander Effect in Caenorhabditis elegans: A Unique Role of the DNA Damage Checkpoint

2016 ◽  
Vol 186 (6) ◽  
pp. 662 ◽  
Author(s):  
Huangqi Tang ◽  
Liangwen Chen ◽  
Lianyun Chen ◽  
Bin Chen ◽  
Ting Wang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Caenorhabditis Elegans ◽  
Bystander Effect ◽  
Dna Damage Checkpoint ◽  
Unique Role ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

The role of oxidative DNA damage in radiation induced bystander effect

2015 ◽  
Vol 356 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Sophia Havaki ◽  
Athanassios Kotsinas ◽  
Efstathios Chronopoulos ◽  
Dimitris Kletsas ◽  
Alexandros Georgakilas ◽  
...  
Keyword(s):  
Dna Damage ◽  
Oxidative Dna Damage ◽  
Bystander Effect ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

scholarly journals Mechanism of radiation-induced bystander effect: Role of the cyclooxygenase-2 signaling pathway

2005 ◽  
Vol 102 (41) ◽  
pp. 14641-14646 ◽  
Author(s):  
H. Zhou ◽  
V. N. Ivanov ◽  
J. Gillespie ◽  
C. R. Geard ◽  
S. A. Amundson ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Bystander Effect ◽  
Cyclooxygenase 2 ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

scholarly journals Radiation induced bystander effect and DNA damage

2014 ◽  
Vol 10 (4) ◽  
pp. 819 ◽  
Author(s):  
Nasir Jalal ◽  
Saba Haq ◽  
Namrah Anwar ◽  
Saadiya Nazeer ◽  
Umar Saeed
Keyword(s):  
Dna Damage ◽  
Bystander Effect ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

Role of Endoplasmic Reticulum and Mitochondrion in Proton Microbeam Radiation-Induced Bystander Effect

2019 ◽  
Vol 193 (1) ◽  
pp. 63 ◽  
Author(s):  
Chen Dong ◽  
Wenzhi Tu ◽  
Mingyuan He ◽  
Jiamei Fu ◽  
Alisa Kobayashi ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Bystander Effect ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

Role of ROS-mediated autophagy in radiation-induced bystander effect of hepatoma cells

2015 ◽  
Vol 91 (5) ◽  
pp. 452-458 ◽  
Author(s):  
Xiangdong Wang ◽  
Jianghong Zhang ◽  
Jiamei Fu ◽  
Juan Wang ◽  
Shuang Ye ◽  
...  
Keyword(s):  
Bystander Effect ◽  
Hepatoma Cells ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

Abstract 574: Mechanism of radiation-induced bystander effect: Role of NFκß pathway

2011 ◽  
Author(s):  
Jamunarani Veeraraghavan ◽  
Mohan Natarajan ◽  
Terence S. Herman ◽  
Natarajan Aravindan
Keyword(s):  
Bystander Effect ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

scholarly journals The Role of Ionizing Radiation in Cellular Signaling Pathways, Mutagenesis, and Carcinogenesis

2019 ◽  
Vol 3 (4) ◽  
pp. 147-153
Author(s):  
sakine rezaiekahkhaie ◽  
Khadije Rezaie Keikhaie
Keyword(s):  
Ionizing Radiation ◽  
Signaling Pathways ◽  
Bystander Effect ◽  
Cellular Signaling ◽  
Cellular Interactions ◽  
Negative Effects ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect ◽  
Ionizing Radiations

One of the negative effects of ionizing radiation is the alteration of cellular signaling pathways which lead to carcinogenesis and tumorigenesis. In this review, we discussed the impacts of ionizing radiation on cells and cellular signaling pathways. In this regard, exposure to radiation can directly or indirectly alter cellular signaling pathways. Remarkably, irradiated cells release special mediators into cellular matrix, aberrating cell-cell and cell-environment interactions. Most notably, these mediators include nitric oxide (NO), reactive oxygen species (ROS), and cell growth factors which contribute to cellular interactions between irradiated cells and their neighbor cells, a phenomenon known as radiation-induced bystander effect. DNA molecule is the most important cellular compartment damaged by ionizing radiation. On the other hand, the ability of irradiated cells to repair the damaged DNA is very low. Therefore, DNA alternations are passed to the next generations, and ultimately lead to carcinogenesis. The study of ionizing radiations and their impacts on biological systems is of remarkable importance to divulge their impacts on cellular signaling pathways.

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