Biomolecular Analysis of Beta Dose-Dependent Cutaneous Radiation Injury in a Porcine Model

2019 ◽  
Vol 192 (2) ◽  
pp. 145
Author(s):  
Luke R. Burnett ◽  
Alexis R. Gabard ◽  
Mac Robinson ◽  
J. Daniel Bourland ◽  
Jennifer E. Dorand ◽  
...  
Keyword(s):  
Radiation Injury ◽  
Porcine Model ◽  
Beta Dose ◽  
Biomolecular Analysis ◽  
Dose Dependent

scholarly journals P298Safety of catheter-free VT ablation: Dose-dependent LVEF changes after proton beam therapy of the LV in a porcine model

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
S Hohmann ◽  
A J Deisher ◽  
A Suzuki ◽  
H Konishi ◽  
M E Rettmann ◽  
...  
Keyword(s):  
Proton Beam ◽  
Porcine Model ◽  
Proton Beam Therapy ◽  
Vt Ablation ◽  
Dose Dependent

Evaluation of Gamma Radiation-Induced Biochemical Changes in Skin for Dose Assesment: A Study on Small Experimental Animals

2018 ◽  
Vol 13 (02) ◽  
pp. 197-202
Author(s):  
Sandeep Kumar Soni ◽  
Mitra Basu ◽  
Priyanka Agrawal ◽  
Aseem Bhatnagar ◽  
Neelam Chhillar
Keyword(s):  
Radiation Dose ◽  
Gamma Radiation ◽  
Radiation Injury ◽  
Acute Radiation ◽  
Dose Assessment ◽  
Whole Body ◽  
Dependent Manner ◽  
Acute Radiation Injury ◽  
Radiation Induced ◽  
Dose Dependent

AbstractObjectiveResearchers have been evaluating several approaches to assess acute radiation injury/toxicity markers owing to radiation exposure. Keeping in mind this background, we assumed that whole-body irradiation in single fraction in graded doses can affect the antioxidant profile in skin that could be used as an acute radiation injury/toxicity marker.MethodsSprague-Dawley rats were treated with CO-60 gamma radiation (dose: 1-5 Gy; dose rate: 0.85 Gy/minute). Skin samples were collected (before and after radiation up to 72 hours) and analyzed for glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase (CAT), and lipid peroxidation (LPx).ResultsIntra-group comparison showed significant differences in GSH, GPx, SOD, and CAT, and they declined in a dose-dependent manner from 1 to 5 Gy (P value<0.01, r value: 0.3-0.5). LPx value increased (P value<0.01, r value: 0.3-0.5) as the dose increased, except in 1 Gy (P value>0.05).ConclusionsThis study suggests that skin antioxidants were sensitive toward radiation even at a low radiation dose, which can be used as a predictor of radiation injury and altered in a dose-dependent manner. These biochemical parameters may have wider application in the evaluation of radiation-induced skin injury and dose assessment. (Disaster Med Public Health Preparedness. 2019;13:197–202).

EP2 receptor null mice have an impaired intestinal response to radiation injury

2001 ◽  
Vol 120 (5) ◽  
pp. A10-A10
Author(s):  
C HOUCHEN ◽  
B DIECKGRAEFE ◽  
M STUMOSKI ◽  
W STENSON
Keyword(s):  
Radiation Injury ◽  
Ep2 Receptor

695: Impact of Arterial and Arteriovenous Renal Clamping with and without Intrarenal Cooling on Renal Oxygenation and Temperature in a Porcine Model

2007 ◽  
Vol 177 (4S) ◽  
pp. 233-233
Author(s):  
Alexandra E. Perks ◽  
Trevor D. Schuler ◽  
Luke Fazio ◽  
Brian Blew ◽  
Greg Hare ◽  
...  
Keyword(s):  
Porcine Model

877: The Effect of Arterial Versus Arteriovenous Clamping on Renal Tissue Oxygenation in a Porcine Model

2006 ◽  
Vol 175 (4S) ◽  
pp. 283-284
Author(s):  
Luke M. Fazio ◽  
Alexandra E. Perks ◽  
Brian D.M. Blew ◽  
Greg T. Hare ◽  
David Mazer ◽  
...  
Keyword(s):  
Tissue Oxygenation ◽  
Porcine Model ◽  
Renal Tissue

637: Establishing a Porcine Model for the Accelerated Development of Cancer Vaccines for Patients with Metastatic Renal Cell Carcinoma

2005 ◽  
Vol 173 (4S) ◽  
pp. 173-174
Author(s):  
Quinton V. Cancel ◽  
Benjamin K. Yang ◽  
Zhen Su ◽  
Jens Dannull ◽  
Philipp Dahm ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Cancer Vaccines ◽  
Porcine Model

44: Laparoscopic Augmentation Cystoplasty: A Comparison between Native Ileum Versus Small Intestinal Submucosa in the Porcine Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 12-12
Author(s):  
David A. Anderson ◽  
David S. Wang ◽  
Peter C. Fretz ◽  
Thai T. Nguyen ◽  
Howard N. Winfield
Keyword(s):  
Porcine Model ◽  
Small Intestinal Submucosa ◽  
Augmentation Cystoplasty ◽  
Small Intestinal ◽  
Intestinal Submucosa
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