In VitroStudy of the Stress Response of Human Skin Cells to GSM-1800 Mobile Phone Signals Compared to UVB Radiation and Heat Shock

2007 ◽  
Vol 167 (5) ◽  
pp. 572-580 ◽  
Author(s):  
S. Sanchez ◽  
E. Haro ◽  
G. Ruffié ◽  
B. Veyret ◽  
I. Lagroye
Keyword(s):  
Stress Response ◽  
Heat Shock ◽  
Mobile Phone ◽  
Human Skin ◽  
Uvb Radiation ◽  
Skin Cells ◽  
Human Skin Cells

scholarly journals Expression of Heat Shock Protein 70 in Human Skin Cells as a Photoprotective Function after UV Exposure

2008 ◽  
Vol 20 (4) ◽  
pp. 184 ◽  
Author(s):  
Byoung Hwa Roh ◽  
Dae Hyun Kim ◽  
Moon Kyun Cho ◽  
Young Lip Park ◽  
Kyu Uang Whang
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Human Skin ◽  
Heat Shock Protein 70 ◽  
Uv Exposure ◽  
Skin Cells ◽  
Human Skin Cells

scholarly journals Differential expression of selenoproteins by human skin cells and protection by selenium from UVB-radiation-induced cell death

1998 ◽  
Vol 332 (1) ◽  
pp. 231-236 ◽  
Author(s):  
Teresa S. RAFFERTY ◽  
Roderick C. McKENZIE ◽  
John A. A. HUNTER ◽  
A. Forbes HOWIE ◽  
John R. ARTHUR ◽  
...  
Keyword(s):  
Cell Death ◽  
Human Skin ◽  
Sodium Selenite ◽  
Human Fibroblasts ◽  
Human Keratinocytes ◽  
Uvb Radiation ◽  
Skin Damage ◽  
Skin Cells ◽  
Radiation Induced ◽  
Human Skin Cells

The generation of reactive oxygen species has been implicated as part of the mechanism responsible for UVB-radiation-induced skin damage. In mice, evidence suggests that increased dietary selenium intake may protect skin from many of the harmful effects of UVB radiation. We sought to determine the selenoprotein profile of cultured human skin cells and whether selenium supplementation could protect keratinocytes and melanocytes from the lethal effects of UVB radiation. Labelling experiments using [75Se]selenite showed qualitative and quantitative differences in selenoprotein expression by human fibroblasts, keratinocytes and melanocytes. This was most noticeable for thioredoxin reductase (60 kDa) and phospholipid glutathione peroxidase (21 kDa); these proteins were identified by Western blotting. Despite these differences, we found that a 24 h preincubation with sodium selenite or selenomethionine protected both cultured human keratinocytes and melanocytes from UVB-induced cell death. With primary keratinocytes, the greatest reduction in cell death was found with 10 nM sodium selenite (79% cell death reduced to 21.7%; P< 0.01) and with 50 nM selenomethionine (79% cell death reduced to 13.2%; P< 0.01). Protection could be obtained with concentrations as low as 1 nM with sodium selenite and 10 nM with selenomethionine. When selenium was added after UVB radiation, little protection could be achieved, with cell death only being reduced from 88.5% to about 50% with both compounds. In all of the experiments sodium selenite was more potent than selenomethionine at providing protection from UVB radiation.

Reduction of UV-light damage in cultured human skin cells after low temperature Heat shock Protein induction

1998 ◽  
Vol 16 ◽  
pp. S228
Author(s):  
Friedhelm Steckel ◽  
Andrea von Stemm ◽  
Wilhelm Meigel ◽  
Gerhard Sauermann ◽  
Udo Hoppe
Keyword(s):  
Heat Shock ◽  
Low Temperature ◽  
Heat Shock Protein ◽  
Human Skin ◽  
Uv Light ◽  
Light Damage ◽  
Skin Cells ◽  
Temperature Heat ◽  
Human Skin Cells
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