PERICARDIAL MESOTHELIOMA AND ASSOCIATED PERICARDIAL EFFUSION IN A TIGER RAT SNAKE (SPILOTES PULLATUS) TREATED WITH PERICARDIOCENTESIS

2021 ◽  
Vol 51 (4) ◽  
Author(s):  
James Yan ◽  
Amelia C. Gould ◽  
Marco L. Margiocco ◽  
Megan Strobel ◽  
Andrea K. Cotter ◽  
...  
2020 ◽  
Vol 12 (3) ◽  
pp. 222-226
Author(s):  
Juan Sebastián Sánchez León ◽  
Irene Lucía Torres Washima ◽  
Anabel Stefanía Cobos Gálvez ◽  
Gladis Margarita Molina Alvarado

BACKGROUND: Primary pericardial mesothelioma is an extremely rare mesodermal tumor, among oncological diseases, with a very low incidence. About 350 cases have been described around the world, most of them diagnosed post-mortem. The short term prognosis is poor, regardless of the treatment, which is mostly palliative. We present a case report regarding this pathology. CASE REPORT: 69 year old patient hospitalized with dyspnea and severe anemia. Complementary workup showed pleural effusion and pericardial effusion. Histopathology report of the pericardial fluid revealed pericardial mesothelioma. EVOLUTION: Due to recurrence of pericardial effusion, it was decided to perform pericardiectomy and left pleurectomy as palliative treatment, to alleviate the patient’s symptoms. Chemotherapy was planned after the procedure, but the patient’s general condition deteriorated severely leading to his death. CONCLUSION: Primary pericardial mesothelioma is a rare tumor, whose symptoms are characterized by the associated pericardial effusion, making the diagnosis difficult due to it low incidence. The prognosis is poor in short- term, and there isn’t an established protocol for the treatment with results that showed improve in mortality. KEYWORDS: MESOTHELIOMA, PERICARDIAL EFFUSION, PERICARDIECTOMY, PLEUROTOMY.


2021 ◽  
Vol 8 ◽  
Author(s):  
Jiahui Liu ◽  
Zhi Wang ◽  
Ying Yang ◽  
Yan Xiong ◽  
Wei Wang ◽  
...  

Background: Primary pericardial mesothelioma is an extremely rare tumor, and early identification and accurate diagnosis may improve its clinical outcome.Case presentation: In this study, we reported a case of a 70-year-old woman who presented with dyspnea. Conventional transthoracic echocardiography showed massive pericardial effusion. Contrast-enhanced ultrasonography revealed a hyper-enhancing mass in the pericardium. Further imaging methods, including cardiac MRI and positron emission tomography/computed tomography, showed invasion of the pericardial mass into the adjacent tissues and distant metastases. Pathologic examination of a puncture biopsy specimen finally confirmed the diagnosis of PPM.Conclusion: Pericardial masses are difficult to detect when a large amount of pericardial effusion is present and the mass is small. The combination of multiple modalities plays a meaningful role in identifying PPM.


2013 ◽  
Vol 49 (6) ◽  
pp. 398-402 ◽  
Author(s):  
Ricardo Guillem Gallach ◽  
Wilfried Mai

Veterinary cardiac MRI (cMRI) is a relatively new technique. A dog with recurrent pericardial effusion and a questionable right atrial mass lesion on echocardiography underwent cMRI. cMRI provided excellent anatomic information about the heart and surrounding structures and helped to rule out the presence of a focal mass. A diffuse thickening and enhancement of the pericardium was detected. Pericardiectomy was performed and histopathology revealed a diffuse pericardial mesothelioma. This case illustrates the potential of cMRI in the management of patients with pericardial effusion when echocardiographic findings are equivocal and illustrates cMRI findings in a case of diffuse pericardial mesothelioma.


2020 ◽  
Vol 31 (2) ◽  
pp. 274-276
Author(s):  
Hongxia Wang ◽  
Yun Mou ◽  
Zhelan Zheng

Abstract Primary malignancies arising from the pericardium are rare, even more unusual for primary pericardial mesothelioma. The diagnosis is difficult and has no standard treatment. We herein present a case of a 65-year-old woman with primary pericardial mesothelioma associated with dyspnoea and palpitations. Transthoracic conventional echocardiography revealed mild pericardial effusion and a hypo-echogenic mass in the pericardium. Contrast echocardiography showed that the mass was hyper-enhanced with a radial enhancement pattern. The patient underwent open chest exploration and was diagnosed by pathological examination. She had no further treatment and died 2 years later. In conclusion, the combination of conventional echocardiography and contrast echocardiography plays a significant role in diagnosing primary pericardial mesothelioma. Comprehensive evaluation and accurately preoperative diagnosis are important to exclude certain tumours that do not require surgery.


2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Morad Tajjiou ◽  
Wolfgang Wild ◽  
Nasir Sayed ◽  
Alexander Flauaus ◽  
Markus Divo ◽  
...  

This case report shows that pleural empyema limits the diagnostic significance of imaging techniques. Hereafter, we present the case of an 82-year-old patient with primary pericardial mesothelioma, which was veiled by a pleural empyema. The patient met the typical triad of signs of heart failure (dyspnea, lower leg oedema), pericardial effusion, and pericarditis. Echocardiography in the identification of pericardial mesotheliomas is low. In this case, the cardiac function could be imaged well, but the tumor could not be imaged. The CT showed a pericardial effusion and a pleural effusion. Here, the tumor could not be diagnosed either. Only the operation led to diagnosis.


2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Valery Istomin ◽  
David S. Blondheim ◽  
Simcha R. Meisel ◽  
Aaron Frimerman ◽  
Moshe Lapidot ◽  
...  

This case report describes a 37-year-old female who was admitted to our Emergency Department because of shortness of breath. On physical examination, she had dyspnea and tachycardia and blood pressure was 80/50 mmHg with a pulsus paradoxus of 22 mmHg. Neck veins were distended, heart sounds were distant, and dullness was found on both lung bases. Her chest X-ray revealed bilateral pleural effusion and cardiomegaly. On both computed tomography and echocardiography the heart was of normal size and a large pericardial effusion was noted. The echocardiogram showed signs of impending tamponade, so the patient underwent an emergent pericardiocentesis. No infectious etiology was found and she was assumed to have viral pericarditis and was treated accordingly. However, when the pericardial effusion recurred and empirical therapy for tuberculosis failed, a pericardial window was performed. A typical staining pattern for mesothelioma was found on her pericardial biopsy specimen. Since no other mesodermal tissue was affected, a diagnosis of primary malignant pericardial mesothelioma was made. Chemotherapy was not effective and she passed away a year after the diagnosis was made. This case highlights the difficulties in diagnosing this uncommon disease in patients that present with the common finding of pericardial effusion.


2016 ◽  
Vol 21 (4) ◽  
pp. 242-245
Author(s):  
Iain Cope ◽  
Matt Fiddes ◽  
Sarah Pellet

2017 ◽  
Vol 02 (02) ◽  
pp. 046-048
Author(s):  
R Kumar ◽  
Sai Surabhi ◽  
◽  

AbstractPrimary pericardial mesothelioma is a rare and lethal tumor, with a reported prevalence of <0.002% [1]. Pleural and pericardial mesotheliomas, which are far more common are usually associated with exposure to asbestos. However, the cause of pericardial mesothelioma is less clear [2] and is influenced by other factors like genetic predisposition, immunological impairment, infection, radiation, dietary factors and recurrent serosal inflammation [3]. Clinical manifestations of the neoplasm include constrictive pericarditis, cardiac tamponade, and heart failure. Because of late presentation and few treatment approaches, primary pericardial mesothelioma carries a poor prognosis. In this paper, we present a case of primary pericardial mesothelioma in a 46 year female presenting as recurrent pericardial effusion along with constrictive pericarditis.


1984 ◽  
Vol 4 (6) ◽  
pp. 1307-1310 ◽  
Author(s):  
Neil L. Coplan ◽  
Arthur J. Kennish ◽  
Nora L. Burgess ◽  
Liane Deligdish ◽  
Martin E. Goldman

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