scholarly journals MIO-M1 Cells and Similar Müller Glial Cell Lines Derived from Adult Human Retina Exhibit Neural Stem Cell Characteristics

Stem Cells ◽  
2007 ◽  
Vol 25 (8) ◽  
pp. 2033-2043 ◽  
Author(s):  
Jean M. Lawrence ◽  
Shweta Singhal ◽  
Bhairavi Bhatia ◽  
David J. Keegan ◽  
Thomas A. Reh ◽  
...  
Keyword(s):  
Stem Cell ◽  
Glial Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Human Retina ◽  
Adult Human ◽  
Müller Glial Cell

Intravascular Delivery of Neural Stem Cell Lines to Target Intracranial and Extracranial Tumors of Neural and Non-Neural Origin

2003 ◽  
Vol 14 (18) ◽  
pp. 1777-1785 ◽  
Author(s):  
Alice B. Brown ◽  
Wendy Yang ◽  
Nils O. Schmidt ◽  
Rona Carroll ◽  
Kim K. Leishear ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Neural Origin ◽  
Stem Cell Lines

Derivation of Haploid Neural Stem Cell Lines by Selection for a Pax6-GFP Reporter

2018 ◽  
Vol 27 (7) ◽  
pp. 479-487 ◽  
Author(s):  
Qian Gao ◽  
Wenhao Zhang ◽  
Lifang Ma ◽  
Xu Li ◽  
Haisong Wang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Gfp Reporter ◽  
Selection For ◽  
Stem Cell Lines

A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies

2020 ◽  
Author(s):  
Barbara Costa ◽  
Michael Fletcher ◽  
Pavle Boskovic ◽  
Ekaterina L. Ivanova ◽  
Tanja Eisemann ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Tumor Model ◽  
Myeloid Cell ◽  
Molecular Heterogeneity ◽  
Double Knockout ◽  
Human Glioblastoma ◽  
Novel Treatments

AbstractGlioblastomas are the most lethal tumors affecting the central nervous system in adults. Simple and inexpensive syngeneic in vivo models that closely mirror human glioblastoma, including interactions between tumor and immune cells, are urgently needed for deciphering glioma biology and developing more effective treatments. Here, we generated glioblastoma cell lines by repeated in-vivo passaging of cells isolated from a neural stem cell-specific Pten/p53 double-knockout genetic mouse brain tumor model. Transcriptome and genome analyses of the cell lines revealed molecular heterogeneity comparable to that observed in human glioblastoma. Upon orthotopic transplantation into syngeneic hosts they formed high-grade gliomas that faithfully recapitulated the histopathological features, invasiveness and myeloid cell infiltration characteristic of human glioblastoma. These features make our cell lines unique and useful tools to study multiple aspects of glioblastoma pathomechanism and test novel treatments, especially immunotherapies in syngeneic preclinical models.

Differential pathotropism of non-immortalized and immortalized human neural stem cell lines in a focal demyelination model

2011 ◽  
Vol 69 (7) ◽  
pp. 1193-1210 ◽  
Author(s):  
Daniela Ferrari ◽  
Cristina Zalfa ◽  
Laura Rota Nodari ◽  
Maurizio Gelati ◽  
Luigi Carlessi ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Human Neural Stem Cell ◽  
Stem Cell Lines ◽  
Focal Demyelination

scholarly journals Systematic Chromosomal Analysis of Cultured Mouse Neural Stem Cell Lines

2011 ◽  
Vol 20 (8) ◽  
pp. 1411-1423 ◽  
Author(s):  
Giuseppe R. Diaferia ◽  
Luciano Conti ◽  
Serena Redaelli ◽  
Monica Cattaneo ◽  
Cesare Mutti ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Chromosomal Analysis ◽  
Stem Cell Lines

Neural Stem Cell Lines for CNS Repair

1999 ◽  
pp. 203-IX ◽  
Author(s):  
Alberto Martínez-Serrano ◽  
Evan Y. Snyder
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Cns Repair ◽  
Stem Cell Lines

scholarly journals Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies

2018 ◽  
Vol 9 (10) ◽  
Author(s):  
Jessica Rosati ◽  
Daniela Ferrari ◽  
Filomena Altieri ◽  
Silvia Tardivo ◽  
Claudia Ricciolini ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Cell Therapies ◽  
Human Neural Stem Cell ◽  
Stem Cell Lines
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