scholarly journals Genome-Wide Differential Gene Expression Profiling of Human Bone Marrow Stromal Cells

Stem Cells ◽  
2007 ◽  
Vol 25 (4) ◽  
pp. 994-1002 ◽  
Author(s):  
Ju Ah Jeong ◽  
Kyung-Min Ko ◽  
Sohyun Bae ◽  
Choon-Ju Jeon ◽  
Gou Young Koh ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Marrow ◽  
Gene Expression Profiling ◽  
Differential Gene Expression ◽  
Stromal Cells ◽  
Expression Profiling ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Genome Wide ◽  
Differential Gene

scholarly journals Large-scale gene expression profiling data of bone marrow stromal cells from osteoarthritic donors

Data in Brief ◽  
2016 ◽  
Vol 8 ◽  
pp. 545-548 ◽  
Author(s):  
Maik Stiehler ◽  
Juliane Rauh ◽  
Cody Bünger ◽  
Angela Jacobi ◽  
Corina Vater ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Marrow ◽  
Gene Expression Profiling ◽  
Stromal Cells ◽  
Expression Profiling ◽  
Bone Marrow Stromal Cells ◽  
Large Scale ◽  
Marrow Stromal Cells

scholarly journals Gene expression profiling of human bone marrow stromal cells with FGFR-3 mutation (K650M) using cDNA microarrays

10.1038/14334 ◽  
1999 ◽  
Vol 23 (S3) ◽  
pp. 53-53
Author(s):  
Libin Jia ◽  
Michael Bittner ◽  
Yidong Chen ◽  
Kris Gooden ◽  
Yuan Jiang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Marrow ◽  
Gene Expression Profiling ◽  
Stromal Cells ◽  
Expression Profiling ◽  
Bone Marrow Stromal Cells ◽  
Cdna Microarrays ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow

scholarly journals Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia

Blood ◽  
2006 ◽  
Vol 107 (4) ◽  
pp. 1570-1581 ◽  
Author(s):  
Yubin Ge ◽  
Alan A. Dombkowski ◽  
Katherine M. LaFiura ◽  
Dana Tatman ◽  
Ravikiran S. Yedidi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Marrow ◽  
Down Syndrome ◽  
Differential Gene Expression ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Target Genes ◽  
Marrow Stromal Cells ◽  
Full Length ◽  
Differential Gene

Children with Down syndrome (DS) with acute megakaryocytic leukemia (AMkL) have very high survival rates compared with non-DS AMkL patients. Somatic mutations identified in the X-linked transcription factor gene, GATA1, in essentially all DS AMkL cases result in the synthesis of a shorter (40 kDa) protein (GATA1s) with altered transactivation activity and may lead to altered expression of GATA1 target genes. Using the Affymetrix U133A microarray chip, we identified 551 differentially expressed genes between DS and non-DS AMkL samples. Transcripts for the bone marrow stromal-cell antigen 2 (BST2) gene, encoding a transmembrane glycoprotein potentially involved in interactions between leukemia cells and bone marrow stromal cells, were 7.3-fold higher (validated by real-time polymerase chain reaction) in the non-DS compared with the DS group. Additional studies confirmed GATA1 protein binding and transactivation of the BST2 promoter; however, stimulation of BST2 promoter activity by GATA1s was substantially reduced compared with the full-length GATA1. CMK sublines, transfected with the BST2 cDNA and incubated with HS-5 bone marrow stromal cells, exhibited up to 1.7-fold reduced cytosine arabinoside (ara-C)-induced apoptosis, compared with mock-transfected cells. Our results demonstrate that genes that account for differences in survival between DS and non-DS AMkL cases may be identified by microarray analysis and that differential gene expression may reflect relative transactivation capacities of the GATA1s and full-length GATA1 proteins.

scholarly journals Differential gene expression profiling of human bone marrow-derived mesenchymal stem cells during adipogenic development

BMC Genomics ◽  
2011 ◽  
Vol 12 (1) ◽  
pp. 461 ◽  
Author(s):  
Adriane Menssen ◽  
Thomas Häupl ◽  
Michael Sittinger ◽  
Bruno Delorme ◽  
Pierre Charbord ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Gene Expression Profiling ◽  
Differential Gene Expression ◽  
Expression Profiling ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Differential Gene
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