Analysis of the Hif1a cistrome in mouse embryonic heart

2019 ◽  
Author(s):  
N Guimarães-Camboa
Keyword(s):  
Embryonic Heart

Activation of STAT3 within the embryonic heart in response to anoxia–reoxygenation

2008 ◽  
Vol 44 (4) ◽  
pp. 792-793
Author(s):  
Sarah Pedretti ◽  
Stéphany Gardier ◽  
Eric Raddatz
Keyword(s):  
Embryonic Heart

Optical approaches to ontogeny of electrical activity and related functional organization during early heart development

1991 ◽  
Vol 71 (1) ◽  
pp. 53-91 ◽  
Author(s):  
K. Kamino
Keyword(s):  
Electrical Activity ◽  
Heart Development ◽  
Functional Organization ◽  
Embryonic Heart ◽  
Optical Recording ◽  
Additional Advantage ◽  
Physiological Functions ◽  
Spontaneous Electrical Activity ◽  
Somite Stage ◽  
Voltage Sensitive Dyes

Direct intracellular measurement of electrical events in the early embryonic heart is impossible because the cells are too small and frail to be impaled with microelectrodes; it is also not possible to apply conventional electrophysiological techniques to the early embryonic heart. For these reasons, complete understanding of the ontogeny of electrical activity and related physiological functions of the heart during early development has been hampered. Optical signals from voltage-sensitive dyes have provided a new powerful tool for monitoring changes in transmembrane voltage in a wide variety of living preparations. With this technique it is possible to make optical recordings from the cells that are inaccessible to microelectrodes. An additional advantage of the optical method for recording membrane potential activity is that electrical activity can be monitored simultaneously from many sites in a preparation. Thus, applying a multiple-site optical recording method with a 100- or 144-element photodiode array and voltage-sensitive dyes, we have been able to monitor, for the first time, spontaneous electrical activity in prefused cardiac primordia in the early chick embryos at the six- and the early seven-somite stages of development. We were able to determine that the time of initiation of the contraction is the middle period of the nine-somite stage. In the rat embryonic heart, the onset of spontaneous electrical activity and contraction occurs at the three-somite stage. In this review, a new view of the ontogenetic sequence of spontaneous electrical activity and related physiological functions such as ionic properties, pacemaker function, conduction, and characteristics of excitation-contraction coupling in the early embryonic heart are discussed.

scholarly journals Differential Expression of CircRNAs in Embryonic Heart Tissue Associated with Ventricular Septal Defect

2018 ◽  
Vol 15 (7) ◽  
pp. 703-712 ◽  
Author(s):  
Heng Liu ◽  
Yin Hu ◽  
Bin Zhuang ◽  
Jing Yin ◽  
Xiao-Hui Chen ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Differential Expression ◽  
Septal Defect ◽  
Heart Tissue ◽  
Embryonic Heart

scholarly journals miR-1/133a Clusters Cooperatively Specify the Cardiomyogenic Lineage by Adjustment of Myocardin Levels during Embryonic Heart Development

PLoS Genetics ◽  
2013 ◽  
Vol 9 (9) ◽  
pp. e1003793 ◽  
Author(s):  
Katharina Wystub ◽  
Johannes Besser ◽  
Angela Bachmann ◽  
Thomas Boettger ◽  
Thomas Braun
Keyword(s):  
Heart Development ◽  
Embryonic Heart
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