scholarly journals Quantitative evaluation of diabetic autonomic neuropathy by using heart rate variations. Determination of the normal range for the diagnosis of autonomic neuropathy.

1985 ◽  
Vol 145 (3) ◽  
pp. 233-241 ◽  
Author(s):  
NOBORU OIKAWA ◽  
MASANORI UMETSU ◽  
TAKAYOSHI TOYOTA ◽  
YOSHIO GOTO
Keyword(s):  
Heart Rate ◽  
Autonomic Neuropathy ◽  
Quantitative Evaluation ◽  
Diabetic Autonomic Neuropathy ◽  
Normal Range

Preservation of the Hypoxic Drive to Breathing in Diabetic Autonomic Neuropathy

1982 ◽  
Vol 63 (1) ◽  
pp. 17-22 ◽  
Author(s):  
P. M. A. Calverley ◽  
D. J. Ewing ◽  
I. W. Campbell ◽  
P. K. Wraith ◽  
H. M. Brash ◽  
...  
Keyword(s):  
Heart Rate ◽  
Autonomic Neuropathy ◽  
Heart Rate Response ◽  
Ventilatory Response ◽  
Diabetic Autonomic Neuropathy ◽  
Co2 Production ◽  
Diabetic Patients ◽  
Normal Range ◽  
Peripheral Chemoreceptors ◽  
Carotid Chemoreceptors

1. Unexplained cardiorespiratory arrests have been reported in patients with diabetic autonomic neuropathy and these could be due to denervation of the carotid chemoreceptors. 2. We have studied the ventilatory response to transient hypoxia () during exercise in 22 male diabetic patients, six with symptomatic and cardiovascular evidence to suggest diabetic autonomic neuropathy (DAN+) and 12 without these features (DAN−). 3. There was no difference in the ventilatory response to transient hypoxia between the different groups of diabetic patients ( in DAN+ patients = −0·9 ± 0·2 litre min−1 kPa−1; in DAN− patients = −1·2 ± 0·6 litres min−1 kPa−1) even allowing for differences in the level of exercise achieved (CO2 production in DAN+ patients = 743 ± 103 ml/min; CO2 production in DAN– patients = 800 ± 144 ml/min). These results fell within our normal range for ventilatory response to transient hypoxia at this level of exercise. 4. The heart rate response to transient hypoxia varied within the groups but was significantly (P < 0·05) less in the patients with established diabetic autonomic neuropathy. 5. We conclude that the peripheral chemoreceptors are intact in diabetic autonomic neuropathy and that other mechanisms must be implicated in the unexpected cardiorespiratory arrests seen in these patients.

scholarly journals An analysis of spectrum components and CCV of heart rate variability on diabetic autonomic neuropathy

1995 ◽  
Vol 115 (3) ◽  
pp. 460-465
Author(s):  
Toshihiro Nishimura ◽  
Souzaburou Yoshihara ◽  
Kazuyuki Nagatsuka ◽  
Takeshi Inoue ◽  
Masao Saito ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Autonomic Neuropathy ◽  
Diabetic Autonomic Neuropathy

Effect of Aldose Reductase Inhibition on Heart Rate Variability in Patients with Severe or Moderate Diabetic Autonomic Neuropathy

1998 ◽  
Vol 15 (2) ◽  
pp. 111-121 ◽  
Author(s):  
Triantaffilos P. Didangelos ◽  
Vasilios G. Athyros ◽  
Dimitrios T. Karamitsos ◽  
Athanasios A. Papageorgiou ◽  
Georgios I. Kourtoglou ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Autonomic Neuropathy ◽  
Aldose Reductase ◽  
Diabetic Autonomic Neuropathy ◽  
Aldose Reductase Inhibition
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