scholarly journals Implementation of the global plan for insecticide resistance management in malaria vectors: Progress, challenges, and the way forward

2016 ◽  
Author(s):  
Janet Hemingway
Keyword(s):  
Insecticide Resistance ◽  
Resistance Management ◽  
Malaria Vectors ◽  
Insecticide Resistance Management ◽  
The Way

scholarly journals Implementation of the global plan for insecticide resistance management in malaria vectors: progress, challenges and the way forward

2015 ◽  
Vol 14 (1) ◽  
Author(s):  
Abraham P Mnzava ◽  
Tessa B Knox ◽  
Emmanuel A Temu ◽  
Anna Trett ◽  
Christen Fornadel ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
Resistance Management ◽  
Malaria Vectors ◽  
Insecticide Resistance Management ◽  
The Way

scholarly journals Review and Meta-Analysis of the Evidence for Choosing between Specific Pyrethroids for Programmatic Purposes

Insects ◽  
2021 ◽  
Vol 12 (9) ◽  
pp. 826
Author(s):  
Natalie Lissenden ◽  
Mara Kont ◽  
John Essandoh ◽  
Hanafy Ismail ◽  
Thomas Churcher ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
Pyrethroid Resistance ◽  
Meta Analysis ◽  
Resistance Management ◽  
Malaria Vectors ◽  
Resistance Testing ◽  
Differential Mortality ◽  
Wild Populations ◽  
Insecticide Resistance Management ◽  
Laboratory Colonies

Pyrethroid resistance is widespread in malaria vectors. However, differential mortality in discriminating dose assays to different pyrethroids is often observed in wild populations. When this occurs, it is unclear if this differential mortality should be interpreted as an indication of differential levels of susceptibility within the pyrethroid class, and if so, if countries should consider selecting one specific pyrethroid for programmatic use over another. A review of evidence from molecular studies, resistance testing with laboratory colonies and wild populations, and mosquito behavioural assays were conducted to answer these questions. Evidence suggested that in areas where pyrethroid resistance exists, different results in insecticide susceptibility assays with specific pyrethroids currently in common use (deltamethrin, permethrin, α-cypermethrin, and λ-cyhalothrin) are not necessarily indicative of an operationally relevant difference in potential performance. Consequently, it is not advisable to use rotation between these pyrethroids as an insecticide-resistance management strategy. Less commonly used pyrethroids (bifenthrin and etofenprox) may have sufficiently different modes of action, though further work is needed to examine how this may apply to insecticide resistance management.

scholarly journals Review and Meta-Analysis of the Evidence for Choosing Between Specific Pyrethroids for Programmatic Purposes.

2021 ◽  
Author(s):  
Natalie Lissenden ◽  
Mara Kont ◽  
John Essandoh ◽  
Hanafy M Ismail ◽  
Thomas S Churcher ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
Pyrethroid Resistance ◽  
Meta Analysis ◽  
Resistance Management ◽  
Malaria Vectors ◽  
Resistance Testing ◽  
Differential Mortality ◽  
Wild Populations ◽  
Insecticide Resistance Management ◽  
Lambda Cyhalothrin

Pyrethroid resistance is widespread in malaria vectors. However, differential mortality in discriminating dose assays to different pyrethroids is often observed in wild populations. When this occurs, it is unclear if this differential mortality should be interpreted as an indication of differential levels of susceptibility within the pyrethroid class, and if so, if countries should consider selecting one specific pyrethroid for programmatic use over another. A review of evidence from molecular studies, resistance testing with laboratory colonies and wild populations, and mosquito behavioural assays was conducted to answer these questions. Evidence suggests that in areas where pyrethroid resistance exists, different results in insecticide susceptibility assays with specific pyrethroids currently in common use (deltamethrin, permethrin, α-cypermethrin and λ-cyhalothrin) are not necessarily indicative of an operationally relevant difference in potential performance. Consequently, it is not advisable to use rotation between these pyrethroids as an insecticide resistance management strategy. Less commonly used pyrethroids (bifenthrin and etofenprox) may have sufficiently different modes of action, though further work would be needed to examine how this may apply to insecticide resistance management.

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