Stable isotope technology for the determination of pest natal origins

2016 ◽  
Author(s):  
Karen Armstrong
Keyword(s):  
Stable Isotope ◽  
Stable Isotope Technology

Vitamin A Value of Plant Food Provitamin A - Evaluated by the Stable Isotope Technologies

2014 ◽  
Vol 84 (Supplement 1) ◽  
pp. 25-29 ◽  
Author(s):  
Guangwen Tang
Keyword(s):  
Stable Isotope ◽  
Vitamin A ◽  
Provitamin A ◽  
Animal Origin ◽  
Plant Food ◽  
Plant Foods ◽  
A Value ◽  
Provitamin A Carotenoids ◽  
Β Carotene

Humans need vitamin A and obtain essential vitamin A by conversion of plant foods rich in provitamin A and/or absorption of preformed vitamin A from foods of animal origin. The determination of the vitamin A value of plant foods rich in provitamin A is important but has challenges. The aim of this paper is to review the progress over last 80 years following the discovery on the conversion of β-carotene to vitamin A and the various techniques including stable isotope technologies that have been developed to determine vitamin A values of plant provitamin A (mainly β-carotene). These include applications from using radioactive β-carotene and vitamin A, depletion-repletion with vitamin A and β-carotene, and measuring postprandial chylomicron fractions after feeding a β-carotene rich diet, to using stable isotopes as tracers to follow the absorption and conversion of plant food provitamin A carotenoids (mainly β-carotene) in humans. These approaches have greatly promoted our understanding of the absorption and conversion of β-carotene to vitamin A. Stable isotope labeled plant foods are useful for determining the overall bioavailability of provitamin A carotenoids from specific foods. Locally obtained plant foods can provide vitamin A and prevent deficiency of vitamin A, a remaining worldwide concern.

Determination of riociguat and its major human metabolite M-1 in human plasma by stable-isotope dilution LCMS/MS

Bioanalysis ◽  
2015 ◽  
Vol 7 (2) ◽  
pp. 193-205 ◽  
Author(s):  
Mark-Jean Gnoth ◽  
Peter-Michael Hopfe ◽  
Waldemar Czembor
Keyword(s):  
Stable Isotope ◽  
Human Plasma ◽  
Isotope Dilution ◽  
Human Metabolite ◽  
Stable Isotope Dilution
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