Characterization of physiological role of potassium ion channels in the arthropod salivary gland

2016 ◽  
Author(s):  
Zhilin Li
Keyword(s):  
Salivary Gland ◽  
Ion Channels ◽  
Physiological Role ◽  
Potassium Ion ◽  
Potassium Ion Channels

50 Hz magnetic fields of varying flux intensity affect cell shape changes in invertebrate immunocytes: The role of potassium ion channels

2002 ◽  
Vol 23 (4) ◽  
pp. 292-297 ◽  
Author(s):  
Enzo Ottaviani ◽  
Davide Malagoli ◽  
Alex Ferrari ◽  
Davide Tagliazucchi ◽  
Angela Conte ◽  
...  
Keyword(s):  
Ion Channels ◽  
Magnetic Fields ◽  
Cell Shape ◽  
Potassium Ion ◽  
Potassium Ion Channels ◽  
Flux Intensity ◽  
Cell Shape Changes ◽  
Shape Changes

Acid-Sensing Ion Channels

2020 ◽  
Author(s):  
Stefan Gründer
Keyword(s):  
Nervous System ◽  
Ion Channels ◽  
Excitatory Synapses ◽  
Detailed Characterization ◽  
High Affinity ◽  
Acid Sensing Ion Channels ◽  
Long Time ◽  
Pathological Pain

Acid-sensing ion channels (ASICs) are proton-gated Na+ channels. Being almost ubiquitously present in neurons of the vertebrate nervous system, their precise function remained obscure for a long time. Various animal toxins that bind to ASICs with high affinity and specificity have been tremendously helpful in uncovering the role of ASICs. We now know that they contribute to synaptic transmission at excitatory synapses as well as to sensing metabolic acidosis and nociception. Moreover, detailed characterization of mouse models uncovered an unanticipated role of ASICs in disorders of the nervous system like stroke, multiple sclerosis, and pathological pain. This review provides an overview on the expression, structure, and pharmacology of ASICs plus a summary of what is known and what is still unknown about their physiological functions and their roles in diseases.

Highly Selective Artificial Potassium Ion Channels Constructed from Pore‐Containing Helical Oligomers

2017 ◽  
Vol 129 (41) ◽  
pp. 12842-12845 ◽  
Author(s):  
Chao Lang ◽  
Xiaoli Deng ◽  
Feihu Yang ◽  
Bing Yang ◽  
Wei Wang ◽  
...  
Keyword(s):  
Ion Channels ◽  
Potassium Ion ◽  
Potassium Ion Channels

Reconstitution of Single Potassium Channels from Bovine Gallbladder Epithelium

1998 ◽  
Vol 26 (4) ◽  
pp. 188-199
Author(s):  
E Kyriacou
Keyword(s):  
Ion Channels ◽  
Gall Bladder ◽  
Lipid Bilayers ◽  
Membrane Vesicle ◽  
Basolateral Membrane ◽  
Molecular Transport ◽  
Membrane Vesicles ◽  
Potassium Ion ◽  
Potassium Ion Channels ◽  
Adult Cattle

The study of molecular transport across gall-bladder epithelium may contribute to our understanding of the pathophysiology of gall-bladder disease. The aim of this study was to reconstitute and characterize single potassium ion channels in bovine gall-bladder epithelial mucosa – both apical and basolateral aspects. Standard subcellular fractionation techniques were used to form either apical or basolateral closed-membrane vesicles from the mucosal epithelium of fresh gall bladders from healthy young adult cattle. Vesicular ion channels were incorporated into voltage-clamped planar lipid bilayers under known ionic conditions and their conductances, reversal potentials, and voltages were characterized. Low-conductance voltage-insensitive apical membrane vesicle channels of at least four conductance levels were found (mean ± SD): 12 ± 4 pS, n = 10; 40 ± 12 pS, n = 4; 273 ± 31 pS, n = 3; and 151 ± 24 pS, n = 5. Conductances of potassium ion channels in basolateral membrane vesicles were in the range 9–450 pS, and these channels included high-conductance calcium-activated potassium-ion channels ‘K(Ca)’ which were voltage- and calcium-dependent.

Potassium Ion Channels and Allergic Asthma

2014 ◽  
pp. 35-45 ◽  
Author(s):  
M. Kocmalova ◽  
M. Oravec ◽  
M. Adamkov ◽  
V. Sadlonova ◽  
I. Kazimierova ◽  
...  
Keyword(s):  
Ion Channels ◽  
Allergic Asthma ◽  
Potassium Ion ◽  
Potassium Ion Channels
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