Evolution of immune priming favored by the low cost of the secondary immune response in the mealworm beetle,Tenebrio molitor

2016 ◽  
Author(s):  
Julien Dhinaut
Keyword(s):  
Immune Response ◽  
Low Cost ◽  
Tenebrio Molitor ◽  
Secondary Immune Response ◽  
Immune Priming ◽  
Mealworm Beetle

scholarly journals A possible role of tachykinin-related peptide on an immune system activity of mealworm beetle, Tenebrio molitor L.

2021 ◽  
Vol 120 ◽  
pp. 104065
Author(s):  
A. Urbański ◽  
N. Konopińska ◽  
J. Lubawy ◽  
K. Walkowiak-Nowicka ◽  
P. Marciniak ◽  
...  
Keyword(s):  
Immune System ◽  
Tenebrio Molitor ◽  
System Activity ◽  
Related Peptide ◽  
Mealworm Beetle

scholarly journals Immune Control of Herpesvirus Infection in Molluscs

Pathogens ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 618
Author(s):  
Jacinta R Agius ◽  
Serge Corbeil ◽  
Karla J Helbig
Keyword(s):  
Immune Response ◽  
Adaptive Immune System ◽  
Herpesvirus Infection ◽  
Viable Option ◽  
Important Species ◽  
Immune Priming ◽  
Adaptive Immune ◽  
Preventative Strategy ◽  
Herpesvirus 1 ◽  
Ostreid Herpesvirus 1

Molluscan herpesviruses that are capable of infecting economically important species of abalone and oysters have caused significant losses in production due to the high mortality rate of infected animals. Current methods in preventing and controlling herpesviruses in the aquacultural industry are based around biosecurity measures which are impractical and do not contain the virus as farms source their water from oceans. Due to the lack of an adaptive immune system in molluscs, vaccine related therapies are not a viable option; therefore, a novel preventative strategy known as immune priming was recently explored. Immune priming has been shown to provide direct protection in oysters from Ostreid herpesvirus-1, as well as to their progeny through trans-generational immune priming. The mechanisms of these processes are not completely understood, however advancements in the characterisation of the oyster immune response has assisted in formulating potential hypotheses. Limited literature has explored the immune response of abalone infected with Haliotid herpesvirus as well as the potential for immune priming in these species, therefore, more research is required in this area to determine whether this is a practical solution for control of molluscan herpesviruses in an aquaculture setting.

Head movements of the mealworm beetle Tenebrio molitor

1980 ◽  
Vol 36 (2) ◽  
pp. 109-115 ◽  
Author(s):  
D. Varj� ◽  
J. Bolz
Keyword(s):  
Tenebrio Molitor ◽  
Head Movements ◽  
Mealworm Beetle

Measles in bone marrow transplant recipients during an outbreak in São Paulo, Brazil

Blood ◽  
2002 ◽  
Vol 99 (1) ◽  
pp. 83-87 ◽  
Author(s):  
Clarisse M. Machado ◽  
Flávio B. Gonçalves ◽  
Cláudio S. Pannuti ◽  
Frederico L. Dulley ◽  
Vanda A. U. F. de Souza
Keyword(s):  
Bone Marrow ◽  
Immune Response ◽  
Marrow Transplant ◽  
First Year ◽  
High Avidity ◽  
Secondary Immune Response ◽  
Measles Vaccine ◽  
Transplant Recipients ◽  
Igg Antibodies ◽  
Measles Outbreak

In 1997, a measles outbreak was identified in São Paulo. Between February and December, 20 185 cases were confirmed. From April to July 1997, a seroepidemiologic survey was conducted to identify the recipients of bone marrow (BM) transplants who were susceptible to measles and the occurrence of measles in this population. A total of 156 patients were screened by enzyme immunoassay (EIA). Patients with IgG titers more than 100 mIU/mL were considered immune. Measles reimmunization records were also reviewed. Thirty-two vaccinated patients underwent serologic evaluation. Six of 22 patients (27.3%) within 3 years after vaccination lost measles immunity, in contrast to 7 of 10 patients (70%) vaccinated longer than 3 years previously (P = .049). Among the 122 nonvaccinated patients, 41 (33.6%) were susceptible to measles: 4 of 47 patients (8.5%) within the first year after BM transplantation (BMT), and 37 of the 75 patients (49.3%) after the first year after BMT (P < .001). Eight recipients acquired measles, confirmed by serology (EIA). High-avidity IgG antibodies were observed in the acute phase of measles, suggesting a secondary immune response. Measles interstitial pneumonia was observed in one patient. Seven patients had mild symptoms. Exanthema was present in all patients. All but one patient had fever and nonproductive cough. Koplik spots could be observed in 5 patients. Measles can be mild in BM transplant recipients. Exanthema is frequently present but not often typical. Immunity to measles decreases after day +365 after BMT. Additional studies are needed to evaluate the safety of measles vaccine after the first year of BMT, mostly during outbreaks.

scholarly journals The epidemiological consequences of immune priming

2012 ◽  
Vol 279 (1746) ◽  
pp. 4505-4512 ◽  
Author(s):  
Hannah J. Tidbury ◽  
Alex Best ◽  
Mike Boots
Keyword(s):  
Immune Response ◽  
Population Dynamics ◽  
Population Level ◽  
Low Doses ◽  
Population Stability ◽  
Invertebrate Immunity ◽  
Invertebrate Host ◽  
Immune Priming ◽  
Pathogen Persistence ◽  
Full Immunity

Exposure to low doses of pathogens that do not result in the host becoming infectious may ‘prime’ the immune response and increase protection to subsequent challenge. There is increasing evidence that such immune priming is a widespread and important feature of invertebrate host–pathogen interactions. Immune priming clearly has implications for individual hosts but will also have population-level implications. We present a susceptible–primed–infectious model—in contrast to the classic susceptible–infectious–recovered framework—to investigate the impacts of immune priming on pathogen persistence and population stability. We describe impacts of immune priming on the epidemiology of the disease in both constant and seasonal environments. A key result is that immune priming may act to destabilize population dynamics. In particular, when the proportion of individuals becoming primed rather than infected is high, but this priming does not confer full immunity, the population may be strongly destabilized through the generation of limit cycles. We discuss the implications of our model both in the context of invertebrate immunity and more widely.

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