Exemplar Abstract for Streptomyces ghanaensis Wallhäusser et al. 1966 (Approved Lists 1980) emend. Nouioui et al. 2018.

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  
Streptomyces Ghanaensis

scholarly journals Genome Engineering Approaches to Improve Nosokomycin A Production by Streptomyces ghanaensis B38.3

2018 ◽  
Vol 59 (1) ◽  
pp. 109-111
Author(s):  
Yuriy Kuzhyk ◽  
Maria Lopatniuk ◽  
Andriy Luzhetskyy ◽  
Victor Fedorenko ◽  
Bohdan Ostash
Keyword(s):  
Genome Engineering ◽  
Streptomyces Ghanaensis

scholarly journals Pleiotropic regulatory genes bldA , adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

Open Biology ◽  
2013 ◽  
Vol 3 (10) ◽  
pp. 130121 ◽  
Author(s):  
Roman Makitrynskyy ◽  
Bohdan Ostash ◽  
Olga Tsypik ◽  
Yuriy Rebets ◽  
Emma Doud ◽  
...  
Keyword(s):  
Metabolic Pathways ◽  
Antibiotic Production ◽  
Genome Mining ◽  
Gene Clusters ◽  
Regulatory Genes ◽  
Structural Genes ◽  
Metabolism Regulation ◽  
Streptomyces Ghanaensis ◽  
Free Gene ◽  
Pleiotropic Regulators

Unlike the majority of actinomycete secondary metabolic pathways, the biosynthesis of peptidoglycan glycosyltransferase inhibitor moenomycin in Streptomyces ghanaensis does not involve any cluster-situated regulators (CSRs). This raises questions about the regulatory signals that initiate and sustain moenomycin production. We now show that three pleiotropic regulatory genes for Streptomyces morphogenesis and antibiotic production— bldA , adpA and absB —exert multi-layered control over moenomycin biosynthesis in native and heterologous producers. The bldA gene for tRNA Leu UAA is required for the translation of rare UUA codons within two key moenomycin biosynthetic genes ( moe ), moeO5 and moeE5 . It also indirectly influences moenomycin production by controlling the translation of the UUA-containing adpA and, probably, other as-yet-unknown repressor gene(s). AdpA binds key moe promoters and activates them. Furthermore, AdpA interacts with the bldA promoter, thus impacting translation of bldA -dependent mRNAs—that of adpA and several moe genes. Both adpA expression and moenomycin production are increased in an absB- deficient background, most probably because AbsB normally limits adpA mRNA abundance through ribonucleolytic cleavage. Our work highlights an underappreciated strategy for secondary metabolism regulation, in which the interaction between structural genes and pleiotropic regulators is not mediated by CSRs. This strategy might be relevant for a growing number of CSR-free gene clusters unearthed during actinomycete genome mining.

The minimal replicon of the Streptomyces ghanaensis plasmid pSG5 identified by subcloning and Tn5 mutagenesis

1988 ◽  
Vol 211 (3) ◽  
pp. 424-429 ◽  
Author(s):  
Günter Muth ◽  
Wolfgang Wohlleben ◽  
Alfred Pühler
Keyword(s):  
Tn5 Mutagenesis ◽  
Streptomyces Ghanaensis

scholarly journals МОНГОЛ ОРНЫ ХӨРСНӨӨС ЯЛГАСАН АКТИНОМИЦЕТИЙН АНГИЛАЛЗҮЙН СУДАЛГААНЫ ДҮНГЭЭС

2016 ◽  
pp. 66-72
Author(s):  
Б Пагмадулам ◽  
Мониша Канна ◽  
Д Цэрэндулам ◽  
Ц Рэнцэнханд
Keyword(s):  
Phylogenetic Analysis ◽  
16S Rrna ◽  
Dna Hybridization ◽  
16S Rrna Genes ◽  
Rrna Genes ◽  
Phenotypic Characteristics ◽  
Genus Streptomyces ◽  
Streptomyces Ghanaensis ◽  
Preliminary Study ◽  
Type Strains

Soil samples were collected from Khentii and Tuv provinces in Mongolia. Two strains (N11, N22) were selected for polyphasic approach which including morphological, physiological and phylogenetic analysis. Phylogenetic analysis revealed that the strain N22 has highest the 16S rRNA similarity of 99.39% with Streptomyces ghanaensis NBRC 15414(T). The 16S rRNA genes sequence of 1418 nucleotides was generated for N11 and compared to the validly described species of genus Streptomyces as closest neighbors. Phylogenetic analysis revealed that the strain N11 has highest the 16S rRNA similarity of 98.51% with Streptomyces yerevanensis NBRC 12517(T). Also some phenotypic characteristics were different from type strains. Preliminary study shows that strain N11 might be new actinomycete species. However, need to determine the genetic distance between two microorganisms by using DNA-DNA hybridization methods.

scholarly journals Gene ssfg_01967 (miaB) for tRNA modification influences morphogenesis and moenomycin biosynthesis in Streptomyces ghanaensis ATCC14672

Microbiology ◽  
2019 ◽  
Vol 165 (2) ◽  
pp. 233-245 ◽  
Author(s):  
Yuliia Sehin ◽  
Oksana Koshla ◽  
Yuriy Dacyuk ◽  
Ruoxia Zhao ◽  
Robert Ross ◽  
...  
Keyword(s):  
Trna Modification ◽  
Streptomyces Ghanaensis
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