Exemplar Abstract for Streptomyces roseosporus Falcão de Morais and Dália Maia 1961 (Approved Lists 1980).

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  
Streptomyces Roseosporus

Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation

ChemBioChem ◽  
2018 ◽  
Vol 19 (16) ◽  
pp. 1716-1719 ◽  
Author(s):  
Yee Hwee Lim ◽  
Fong Tian Wong ◽  
Wan Lin Yeo ◽  
Kuan Chieh Ching ◽  
Yi Wee Lim ◽  
...  
Keyword(s):  
Streptomyces Roseosporus

scholarly journals Identification of novel mureidomycin analogues via rational activation of a cryptic gene cluster in Streptomyces roseosporus NRRL 15998

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Lingjuan Jiang ◽  
Lu Wang ◽  
Jihui Zhang ◽  
Hao Liu ◽  
Bin Hong ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Streptomyces Roseosporus

scholarly journals MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus

2013 ◽  
Vol 67 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Wei-Ting Liu ◽  
Anne Lamsa ◽  
Weng Ruh Wong ◽  
Paul D Boudreau ◽  
Roland Kersten ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Genome Mining ◽  
Streptomyces Roseosporus

scholarly journals DepR1, a TetR Family Transcriptional Regulator, Positively Regulates Daptomycin Production in an Industrial Producer, Streptomyces roseosporus SW0702

2016 ◽  
Vol 82 (6) ◽  
pp. 1898-1905 ◽  
Author(s):  
Peng-Hui Yuan ◽  
Ri-Cheng Zhou ◽  
Xuepeng Chen ◽  
Shuai Luo ◽  
Feng Wang ◽  
...  
Keyword(s):  
Genetic Engineering ◽  
Direct Interaction ◽  
Morphological Differentiation ◽  
Transcriptional Regulator ◽  
Mobility Shift ◽  
Positive Role ◽  
Content Type ◽  
Positive Effects ◽  
Streptomyces Roseosporus ◽  
Daptomycin Production

ABSTRACTDaptomycin is a potent cyclic lipopeptide antibiotic. It is widely used against various Gram-positive bacterial pathogens. Historically, a poor understanding of the transcriptional regulation of daptomycin biosynthesis has limited the options for targeted genetic engineering toward titer improvement. Here, we isolated a TetR family transcriptional regulator, DepR1, from the industrial producerStreptomyces roseosporusSW0702 using a biotinylateddptEpromoter (dptEp) as a probe. The direct interaction between DepR1 anddptEpthen was confirmed by electrophoretic mobility shift assays and DNase I footprinting assays. The deletion ofdepR1led to a reduction indptEpactivity and the cessation of daptomycin production. TheΔdepR1mutant produced less red pigment and failed to sporulate on R5 medium. This suggests that DepR1 plays a positive role in the control of morphological differentiation. Moreover, DepR1 was positively autoregulated by directly binding to its own promoter. This might account for the positive feedback regulation of daptomycin production. Based on these positive effects, genetic engineering by overexpression ofdepR1raised daptomycin production and shortened the fermentation period both in flask and in fermentor.

Unexpected extensive lysine acetylation in the trump-card antibiotic producer Streptomyces roseosporus revealed by proteome-wide profiling

2014 ◽  
Vol 106 ◽  
pp. 260-269 ◽  
Author(s):  
Guojian Liao ◽  
Longxiang Xie ◽  
Xin Li ◽  
Zhongyi Cheng ◽  
Jianping Xie
Keyword(s):  
Lysine Acetylation ◽  
Streptomyces Roseosporus ◽  
Trump Card

Kinetic Analysis and Modeling of Daptomycin Batch Fermentation by Streptomyces roseosporus

2010 ◽  
Vol 163 (4) ◽  
pp. 453-462 ◽  
Author(s):  
Wenyu Lu ◽  
Jinghua Fan ◽  
Jianping Wen ◽  
Zhendong Xia ◽  
Qinggele Caiyin
Keyword(s):  
Kinetic Analysis ◽  
Batch Fermentation ◽  
Streptomyces Roseosporus
Sign in / Sign up

Export Citation Format

Share Document