Classification of Cleft Lip/Palate: Then and Now

2017 ◽  
Vol 54 (2) ◽  
pp. 175-188 ◽  
Author(s):  
Alexander C. Allori ◽  
John B. Mulliken ◽  
John G. Meara ◽  
Stephen Shusterman ◽  
Jeffrey R. Marcus
Keyword(s):  
Cleft Lip ◽  
Shorthand Notation ◽  
Cleft Lip Palate ◽  
Evolution Of Ideas

Cleft lip and/or palate (CL/P) is phenotypically diverse, making classification difficult. This article explores the evolution of ideas regarding CL/P classification and includes the schemes described by Davis and Ritchie (1922) , Brophy (1923) , Veau (1931) , Fogh-Andersen (1943), Kernahan and Stark (1958) , Harkins et al. (1962) , Broadbent et al. (1968), Spina (1973) , and others. Based on these systems, a longhand structured form is proposed for describing CL/P in a way that is clear, comprehensive, and consistent. A complementary shorthand notation is also described to improve the utility and convenience of this structured form.

Clinician's Primer to ICD-10-CM Coding for Cleft Lip/Palate Care

2017 ◽  
Vol 54 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Alexander C. Allori ◽  
Janet D. Cragan ◽  
Gina C. Delia Porta ◽  
John B. Mulliken ◽  
John G. Meara ◽  
...  
Keyword(s):  
United States ◽  
Cleft Lip ◽  
International Classification Of Diseases ◽  
The United States ◽  
Care Community ◽  
Diagnostic Coding ◽  
Classification Of Diseases ◽  
Icd 10 ◽  
Cleft Lip Palate

On October 1,2015, the United States required use of the Clinical Modification of the International Classification of Diseases, 10th Revision (ICD-10-CM) for diagnostic coding. This primer was written to assist the cleft care community with understanding and use of ICD-10-CM for diagnostic coding related to cleft lip and/or palate (CL/P).

Clinical Outcomes Utilizing a “Modified Latham” Appliance for Presurgical Infant Orthopedics in Patients With Unilateral Complete Cleft Lip and Palate

2018 ◽  
Vol 56 (7) ◽  
pp. 929-935 ◽  
Author(s):  
Diana S. Jodeh ◽  
Stephen Ruso ◽  
Randy Feldman ◽  
Ernesto Ruas ◽  
S. Alex Rottgers
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Retrospective Chart Review ◽  
International Classification Of Diseases ◽  
Average Hospital ◽  
Classification Of Diseases ◽  
Cleft Lip Palate ◽  
Direct Approximation ◽  
Infant Orthopedics

Presurgical infant orthopedic manipulation is utilized prior to cleft lip/nasal repair to facilitate a gingivoperiosteoplasty (GPP) and primary nasolabial repairs. The Latham dentomaxillary advancement appliance uses a screw that must be tightened daily to approximate the cleft segments in unilateral complete clefts. Our cleft center has been utilizing a “modified Latham” appliance since 1987, including an orthodontic elastic power chain to close the gap in a shorter amount of time. We performed a retrospective chart review of all patients undergoing treatment at Johns Hopkins All Children's Hospital (JHACH) with a unilateral complete cleft lip and palate between 1987 and 2017. Patients were identified by the International Classification of Diseases, Ninth Revision code (749.21). The majority of the patients represent the experience of the senior authors (E.R. and R.F.). Two hundred and eighty-one patients with unilateral complete cleft lip/palate were identified. Seventy-five patients were treated with a “modified Latham” appliance prior to their lip repair. The “modified Latham” appliance remained in place on average 20.6 days (range: 4-82), and average hospital stay after placement was 1.18 days. Nearly 96% of patients underwent a successful GPP at the time of nasolabial repair. Modification of the Latham appliance by utilizing an elastic power chain and eliminating the screw allows rapid closure of the alveolar cleft with limited need for adjustments and outpatient visits. Direct approximation of the palatal segments allows successful completion of a GPP in 95.9% of patients with limited dissection.

scholarly journals Advantages of using toothpaste containing propolis and plant oils for gingivitis prevention and oral cavity hygiene in cleft lip/palate patients

2021 ◽  
Vol 142 ◽  
pp. 111992
Author(s):  
Agnieszka Machorowska-Pieniążek ◽  
Tadeusz Morawiec ◽  
Marcin Olek ◽  
Anna Mertas ◽  
David Aebisher ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Cleft Lip ◽  
Plant Oils ◽  
Cleft Lip Palate

scholarly journals Isoform-Specific Roles of Mutant p63 in Human Diseases

Cancers ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 536
Author(s):  
Christian Osterburg ◽  
Susanne Osterburg ◽  
Huiqing Zhou ◽  
Caterina Missero ◽  
Volker Dötsch
Keyword(s):  
Cleft Lip ◽  
Ectodermal Dysplasia ◽  
Skin Development ◽  
Disease Mechanisms ◽  
Skin Fragility ◽  
Cleft Lip Palate ◽  
Life Threatening ◽  
Functional Consequences ◽  
Development And Differentiation

The p63 gene encodes a master regulator of epidermal commitment, development, and differentiation. Heterozygous mutations in the DNA binding domain cause Ectrodactyly, Ectodermal Dysplasia, characterized by limb deformation, cleft lip/palate, and ectodermal dysplasia while mutations in in the C-terminal domain of the α-isoform cause Ankyloblepharon-Ectodermal defects-Cleft lip/palate (AEC) syndrome, a life-threatening disorder characterized by skin fragility, severe, long-lasting skin erosions, and cleft lip/palate. The molecular disease mechanisms of these syndromes have recently become elucidated and have enhanced our understanding of the role of p63 in epidermal development. Here we review the molecular cause and functional consequences of these p63-mutations for skin development and discuss the consequences of p63 mutations for female fertility.

scholarly journals Alveolar cleft and maximum cleft width as predictors for difficult laryngoscopy and intubation in patients with unilateral complete cleft lip and palate

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Gamal A. Abdelhameed ◽  
Wael A. Ghanem ◽  
Simon H. Armanios ◽  
Tamer Nabil Abdelrahman
Keyword(s):  
Body Weight ◽  
Odds Ratio ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Difficult Laryngoscopy ◽  
Secondary Outcome ◽  
Pediatric Airway ◽  
Alveolar Cleft ◽  
Cleft Lip Palate ◽  
Width Measurements

Abstract Background Cleft lip and palate is one of the commonest congenital anomalies, which have an impact on feeding, speech, and dental development away from the significant psychosocial sequel. Early surgical repair aims to restore appearance and function, and the modern techniques can leave many defects undetectable. Therefore, the anesthetic challenge facing the pediatric airway with such abnormalities is still of a great impact. The aim of our study among 189 patients enrolled is to correlate alveolar gap and maximum cleft width measurements as predictors of difficult laryngoscopy and intubation in infants with unilateral complete cleft lip/palate aging from 1 to 6 months. As a secondary outcome, their weight is to be correlated too as another parameter. Results The alveolar gap and maximum cleft width are both of equal high predictive power (p value ≤ 0.001) with 100% sensitivity for both and specificity of 76.10% and 82.39% respectively, with a cut off value of ≤ 10 mm and 11 mm for these dimensions respectively, and odds ratio of incidence of difficult intubation is 4.18 and 5.68 respectively, while body weight ≤ 5.75 kg has an odds ratio of 2.32. Conclusion Alveolar cleft and maximum cleft width can be used as predictors for anticipation of difficult laryngoscopy and intubation infant patients with unilateral complete cleft lip and palate, while body weight ≤ 5.75 kg increases the risk more than twice.

A novel H208DTP63mutation in a familial case of ectrodactyly–ectodermal dysplasia–cleft lip/palate syndrome without clefting

2009 ◽  
Vol 34 (8) ◽  
pp. e726-e728 ◽  
Author(s):  
L. Sorasio ◽  
E. Biamino ◽  
E. Garelli ◽  
G. B. Ferrero ◽  
M. C. Silengo
Keyword(s):  
Cleft Lip ◽  
Familial Case ◽  
Cleft Lip Palate
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