The Role of Keratinized Mucosa in Peri-Implant Health

2012 ◽  
Vol 49 (2) ◽  
pp. 167-170 ◽  
Author(s):  
Luis Augusto Esper ◽  
Samuel Barros Ferreira ◽  
Rosane de Oliveira Fortes Kaizer ◽  
Ana Lúcia Pompéia Fraga de Almeida
Keyword(s):  
Dental Implants ◽  
Cleft Lip ◽  
Clinical Parameters ◽  
Tertiary Referral ◽  
Tertiary Referral Hospital ◽  
Probing Depth ◽  
Significant Difference ◽  
The Relationship ◽  
Keratinized Mucosa

Objective To evaluate the role of keratinized mucosa around dental implants, correlating with other clinical parameters related to the success of dental implants. Design Cross-section. Setting Institutional tertiary referral hospital. Patients A total of 202 dental implants fixed in the cleft area of 109 patients with cleft lip and/or palate were evaluated. Interventions The evaluated clinical parameters were probing depth and gingival and plaque indexes on the buccal surface (three sites). Main Outcome Measures All clinical parameters were correlated with the width of keratinized mucosa around the implants. Results The largest probing depths were detected when the width of keratinized mucosa was 2 mm or more, with a statistically significant difference between the means of the probing depth and keratinized mucosa width. Conclusion Even though the present results suggest that peri-implant health can be observed in areas with keratinized mucosa width under 2 mm provided an adequate oral hygiene control is performed, longitudinal randomized studies are necessary to analyze the relationship between the width of keratinized mucosa and the health of peri-implant tissues.

scholarly journals Treatment of Polypharmacy Overdose with Multimodality Extracorporeal Life Support

2005 ◽  
Vol 33 (1) ◽  
pp. 120-123 ◽  
Author(s):  
G. Maclaren ◽  
W. Butt ◽  
P. Cameron ◽  
A. Preovolos ◽  
R. Mcegan ◽  
...  
Keyword(s):  
Emergency Department ◽  
Life Support ◽  
Slow Release ◽  
Extracorporeal Life Support ◽  
Tertiary Referral ◽  
Severe Metabolic Acidosis ◽  
Verapamil Overdose ◽  
Tertiary Referral Hospital ◽  
Venoarterial Extracorporeal Membrane Oxygenation

A 45-year-old woman presented to the emergency department of a tertiary referral hospital after taking an overdose of verapamil, doxepin, quetiapine, diazepam, temazepam, and clonazepam. She rapidly developed shock refractory to pharmacological support and was placed on percutaneous venoarterial extracorporeal membrane oxygenation (ECMO). She had a severe metabolic acidosis from a combination of shock and drug intoxication that improved with continuous venovenous haemodialysis. Forty-eight hours after presentation, while still on ECMO, the patient had complete cardiac standstill for three and a half hours, attributable to slow-release verapamil, that resolved after the commencement of plasmapheresis. The role of plasmapheresis in verapamil overdose requires further study.

scholarly journals Role of Santri Middle Class in Democratization Process in Indonesia

2020 ◽  
Vol 6 (2) ◽  
pp. 107-124
Author(s):  
Agus Darmaji
Keyword(s):  
Middle Class ◽  
Relative Deprivation ◽  
Public Services ◽  
Democratic Institutions ◽  
Economic Information ◽  
Political Resources ◽  
Significant Difference ◽  
Independent Variable ◽  
The Relationship

Research on the Roleof Santri Middle Class in Democratization Process in Indonesia was conducted in three cities in Java, i.e. the Cities of East Jakarta, Yogyakarta, and Surabaya. The research was conducted by using quantitative approach and survey method. The data collection method used in this research is direct interview technique, by using questionnaire instrument that was asked to the respondents directly through face to face.There are two types of hypotheses to be proved through this survey research, they are associative and comparativehypotheses.The associative hypothesis verification aims to prove whether there is significant relationship between dependent variable (Y) and independent variable (X) as predictor or not. Inthis research context, the relationship between role in the democratization process as the dependent variable (Y) with predictor independent variables(X) will be tested, which are the literacy of political and economic information(X1), satisfaction to public services (X2), trust in democratic institutions (X3), access to political resources (X4), ideology (X5), and relative deprivation (X6).The comparative hypothesisverificationaims to prove whether there is significant difference between two or more different respondent groups or not. Based on this research purpose, the differences of two respondent groups will be proved comparatively related to their role in the democratization process; they are (1) santrimiddle-class group and (2) groups of santrinon-middle class.There are two types of hypotheses to be proved through this survey research, they are associative and comparative hypotheses. The associative hypothesis verification aims to prove whether there is significant relationship between dependent variable (Y) and independent variable (X) as predictor or not. In this research context, the relationship between role in the democratization process as the dependent variable (Y) with predictor independent variables (X) will be tested, which are the literacy of political and economic information (X1), satisfaction to public services (X2), trust in democratic institutions (X3), access to political resources (X4), ideology (X5), and relative deprivation (X6). The comparative hypothesis verification aims to prove whether there is significant difference between two or more different respondent groups or not. Based on this research purpose, the differences of two respondent groups will be proved comparatively related to their role in the democratization process; they are (1) santri middle-class group and (2) groups of santri non-middle class.From the result of hypothesis associative verification, it is proved that all variables X correlated positively and significantly to variable Y. With this result, then the literacy of political and economic information (X1), satisfaction to public services (X2), trust in democratic institutions (X3), access to political resources (X4), ideology (X5), and relative deprivation (X6) are proved to correlate positively and significantly to the role in democratization (Y).From the result of comparative hypothesis verification, the X2 value of 1363.44 is obtained. This value is greater than the X2 value of table at 88 degrees of freedom and significance level of 0.5. With this result, then the null hypothesis which stated that there is no significant difference between santri middle class and other class groups is rejected. This means the alternative hypothesis that stated otherwise is received. Conclusion based on this examination result is that there are significant differences between the role of santri middle class and other group samples in the democratization process.

scholarly journals Comparison of Relationship between Quality of Public Life and Quality Dedicated to Working Life in the Presence of the Mediator role of Work Conflict: A Multi-Group Analysis

2018 ◽  
Author(s):  
Mohtaram Zabihi ◽  
Ghahraman Mahmoudi ◽  
Ghassem Abedi
Keyword(s):  
Public Life ◽  
Health Sector ◽  
Working Life ◽  
Work Life ◽  
Significant Difference ◽  
Mediator Role ◽  
Job Group ◽  
The Relationship

Background and purpose: The concepts of work and life have the strongest and most effective relationship with individuals and society, and making a balance between them can have a direct impact on the achievement of organizational goals. The purpose of this study was to compare the relationship between quality of public life and quality dedicated to working life in the presence of the mediator role of work conflict.Materials and Methods: This applied study was conducted by implementing a descriptive-analytical method in 2017. The study population consisted of 351 working women in the health sector of Mazandaran University of Medical Sciences, who were selected using stratified sampling method. The survey tool was a standard questionnaire which was used to collect the data, and then the collected data was analyzed by SPSS 24 and AMOS 22.Results: The relationship between quality of public life and quality dedicated to work life in the job groups of women’s healthcare providers (P=0.0009,t=3.592), nurses and midwives' job group (P=0.009,t=2.595), and women’s technician/health expert working in health sector was significant (P=0.002, t=3.104). Whereas, there was no significant difference between the average quality of public life (P=0.117, F=1.788) and the quality dedicated to working life among the employees with different job titles (P=0.592, F=0.742). At the same time, the average of work conflicts was significantly different among different occupations (p = 0.009, F=3.152).Conclusion: The results showed that the relationship between quality of public life and the quality dedicated to work life varies from one job group to another. As a result, with proper planning aiming at increasing the quality of public life, an increase in the quality dedicated to work life and a reduction in their work conflicts can be seen.

scholarly journals Role of Interleukin-6 and Interleukin-8 Cytokines as Early Diagnostic Markers of Sepsis

2020 ◽  
Vol 6 (2) ◽  
pp. 34-38
Author(s):  
Mohammad Moniruzzaman ◽  
Ashesh Kumar Chowdhury ◽  
ASM Areef Ahsan ◽  
Md Zakiur Rahman ◽  
Saimun Nahar Rumana ◽  
...  
Keyword(s):  
Metabolic Disorders ◽  
Serum Levels ◽  
Clinicopathological Parameters ◽  
Enzyme Linked Immunosorbent Assay ◽  
Significant Difference ◽  
Relationship Of ◽  
The Relationship ◽  
Culture Positive ◽  
Control Study

Background: Rapid diagnosis is essential for effective therapy among the patients with sepsis. Objectives: The purpose of the present study was to determine the relationship of serum levels of IL-6, IL-8 in patients with various stages of sepsis. Methodology: This case control study was conducted in the Department of Immunology at Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka from January 2015 to December 2015 for a period of one (01) year. All patients had been selected from the ICU of BIRDEM General Hospital with known clinicopathological parameters of sepsis. Serum levels of IL-6 and IL-8 were assessed using Enzyme Linked Immunosorbent Assay (ELISA) method. Results: In this study, a total of 80 subjects was enrolled of which 60 patients were with at least 2 SIRS criteria and 20 healthy age matched controls without SIRS. Significant difference was found in IL-6 and IL-8 values in the patients with bacteriological culture positive and negative group (p<0.05). AUC for IL-6 was 0.710 (95% CI 0.580-0.840), sensitivity 54.16%, specificity 59.09%, PPV 74.28% and NPV 52% with cutoff value >177pg/ml. Conclusion: Elevated levels of serum IL-6 and IL-8 is found in the patients with sepsis Bangladesh Journal of Infectious Diseases 2019;6(2):34-38

scholarly journals Comparative Analysis of Clinical Parameters and Sputum Biomarkers in Establishing the Relevance of Filamentous Fungi in Cystic Fibrosis

2021 ◽  
Vol 10 ◽  
Author(s):  
Deepa Patel ◽  
Keith Chester Dacanay ◽  
Catherine H. Pashley ◽  
Erol A. Gaillard
Keyword(s):  
Filamentous Fungi ◽  
Stable State ◽  
Fungal Culture ◽  
Clinical Parameters ◽  
Intravenous Antibiotic ◽  
Positive Group ◽  
Significant Difference ◽  
Biomarker Analysis ◽  
Parametric Testing

BackgroundThe relationship between fungal culture (FC) positivity and airway inflammation in CF is largely unknown. Identifying the clinical significance of filamentous fungi in CF using both clinical parameters and biomarkers may change our antimicrobial therapeutic strategies.ObjectivesTo investigate the clinical characteristics and airway biomarker profile in relation to the detection of filamentous fungi in respiratory samples obtained from CF patients.MethodsA prospective cohort study over 24 months, including children and adults with CF. Participants provided sputum and/or bronchoalveolar lavage samples, which underwent processing for bacterial and fungal culture, leukocyte differential cell count and biomarker analysis for neutrophil elastase (NE), interleukin-8 (IL-8), galactomannan and tumor necrosis factor receptor type 2 (TNF-R2). We performed FC using neat sputum plugs, an approach shown to be more sensitive compared to routine laboratory testing.ResultsSixty-one patients provided 76 respiratory samples (72 sputum and 4 BAL). Median age was 17 years (range 6 months–59 years). FC positivity was noted in 49% of the cohort. FC positivity was greater during pulmonary exacerbation compared to the stable state (67 versus 50%). Participants aged 5–30 years had a lower FEV1 within the FC positive group. A significant association between FC positivity and non-tuberculosis mycobacterial (NTM) culture was observed on non-parametric testing (p = 0.022) and regression analysis (p = 0.007). Exposure to indoor mold was a predictor for FC positivity (p = 0.047). There was a trend towards increased lung clearance index (LCI), bronchiectasis and intravenous antibiotic use in the FC positive group. There was no significant difference in biomarkers between FC positive and negative patients.ConclusionAspergillus. fumigatus is the commonest filamentous fungi cultured from CF airways. We found no difference in the airway biomarker profile between FC positive and negative patients. The role of galactomannan and TNFR2 as fungal specific biomarkers in CF remains uncertain. FC positivity is associated with a lower FEV1 in younger patients, a lower LCI, NTM positivity, bronchiectasis, and intravenous antibiotic exposure. Larger trials are needed to determine the role of galactomannan and TNF-R2 as potential fungal biomarkers in CF.

scholarly journals Venous thromboembolism and COVID-19: a single center experience from an academic tertiary referral hospital of Northern Italy

2020 ◽  
Author(s):  
Federica Melazzini ◽  
◽  
Marta Colaneri ◽  
Federica Fumoso ◽  
Giulia Freddi ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Inverse Correlation ◽  
Serum Levels ◽  
Northern Italy ◽  
Referral Hospital ◽  
Clinical Predictors ◽  
Tertiary Referral ◽  
Tertiary Referral Hospital ◽  
Inflammatory Status ◽  
Significant Difference

AbstractPreliminary evidence supports the notion that COVID-19 patients may have an increased susceptibility to develop venous thromboembolism (VTE). However, the magnitude of this association still needs to be defined. Furthermore, clinical predictors of thrombogenesis, and the relationship with the inflammatory status are currently unknown. On this basis, we conducted a retrospective, observational study on 259 consecutive COVID-19 patients admitted to an academic tertiary referral hospital in Northern Italy between March 19th and April 6th, 2020. Records of COVID-19 patients with a definite VTE event were reviewed for demographic information, co-morbidities, risk factors for VTE, laboratory tests, and anticoagulation treatment. Twenty-five cases among 259 COVID-19 patients developed VTE (9.6%), all of them having a Padua score > 4, although being under standard anticoagulation prophylaxis since hospital admission. In the VTE subcohort, we found a significant positive correlation between platelet count (PLT) and either C reactive protein (CRP) (p < 0.0001) or lactate dehydrogenase (LDH) (p = 0.0013), while a significant inverse correlation was observed between PLT and mean platelet volume (p < 0.0001). Platelet-to-lymphocyte ratio significantly correlated with CRP (p < 0.0001). The majority of VTE patients was male and younger compared to non-VTE patients (p = 0.002 and p = 0.005, respectively). No significant difference was found in d-dimer levels between VTE and non VTE patients, while significantly higher levels of LDH (p = 0.04) and IL-6 (p = 0.04) were observed in VTE patients in comparison to non-VTE patients. In conclusion, our findings showed a quite high prevalence of VTE in COVID-19 patients. Raised inflammatory indexes and increased serum levels of pro-inflammatory cytokines should raise the clinical suspicion of VTE.

scholarly journals Unexpected Role of Rotavirus G3P[8] Infection in Causing Severe Diarrhea in a Major Tertiary Referral Hospital in the Prevaccine Era

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Wassim Chehadeh
Keyword(s):  
Nucleotide Sequences ◽  
Referral Hospital ◽  
Tertiary Referral ◽  
Tertiary Referral Hospital ◽  
Rotavirus A ◽  
Severe Diarrhea ◽  
National Immunization ◽  
Severe Gastroenteritis ◽  
Stool Samples

Background: Rotavirus A species is associated with severe gastroenteritis in children. Rotavirus G1P[8] was the most prevalent genotype found in Kuwait in a study conducted between 2005 and 2006. The RotaTeq vaccine was included in the Kuwait national immunization program at the end of 2017. Objectives: Since there is no available data on the rotavirus genotypes circulating before the introduction of the vaccine, we conducted a study to investigate the role of rotaviruses in causing severe diarrhea in children hospitalized in a major tertiary referral hospital in Kuwait during the year 2016. Methods: Viral RNA was isolated from the stool samples of 101 children under five years of age, hospitalized for acute gastroenteritis. Rotavirus VP4 and VP7 dsRNA were detected by RT-PCR, and their partial sequences were analyzed by phylogenic analysis. Results: Rotavirus dsRNA was detected in 24.7% of children with median age of 1 year. The genotype G3P[8] accounted for 47% of cases, followed by G1P[8] (26%), G9P[8] (10.5%), G4P[8] (10.5%), and G9P[4] (5%). Only VP7 nucleotide sequences of rotavirus G3 or G4 type clustered in the same lineage as RotaTeq vaccine, while most VP4 nucleotide sequences of rotavirus P[8] type clustered in a different lineage compared to Rotarix and RotaTeq vaccines. Conclusions: Our findings highlight the role of rotavirus G3P[8] in causing severe diarrhea and invites future investigations to know whether the recent introduction of RotaTeq vaccine in Kuwait selects certain genotypes and subgenomic lineages.

scholarly journals The role of different serotypes and dengue virus concentration in the prognosis of dengue shock syndrome in children

2019 ◽  
Vol 10 (3) ◽  
Author(s):  
Tram Van Ta ◽  
Hai Thanh Tran ◽  
Quyen Nguyen Than Ha ◽  
Xuong Tuyet Nguyen ◽  
Vu Kien Tran ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Dengue Infection ◽  
Dengue Shock Syndrome ◽  
Denv Infection ◽  
Virus Concentration ◽  
Denv Serotypes ◽  
Significant Difference ◽  
Almost All ◽  
The Relationship

Dengue haemorrhagic fever (DHF) is a burden of disease in tropical countries, caused by any one of four-dengue virus (DENV) serotypes (DENV-1 to DENV-4). Although there have been many studies on patients with DHF, many things remain unclear, including the role of DENV serotypes and DENV concentration. The objective of this study was to determine the role of different serotypes and DENV concentration in the prognosis of dengue shock syndrome. This was a prospective cohort study, conducted to show information relating to patients’ conditions, such as hematocrit, platelet, leukocytes, and DENV concentration and the differences between DENV serotypes. The study also expressed the relationship between two groups, DHF without shock and DHF with shock, in terms of immune status, different DENV serotypes, and DENV concentration. Two-hundred and thirty-four patients were serologically confirmed as having a DENV infection. On hospital admission day (fever within 72 hours), results showed that almost all patients had a secondary dengue infection (76.5 %). DENV-1 accounted for the highest number of cases (61.11%), and DENV-4 accounted for the lowest (0.43%). No statistically significant difference was found when comparing the two groups (DHF with shock and DHF without shock) or when comparing the groups of different DENV serotypes. The study concluded that different DENV serotypes or DENV concentration in the first day of hospitalization (fever within 72 hours) cannot be used for prognostic of DSS.

Effect of Hope on Resilience in Adolescents: Social Support and Social Connectedness as Mediators

2021 ◽  
Vol 5 (2) ◽  
pp. 136-147
Author(s):  
İlhan Cicek
Keyword(s):  
Social Support ◽  
High School Students ◽  
Social Connectedness ◽  
School Students ◽  
Mediating Role ◽  
Resilience Scale ◽  
Significant Difference ◽  
Study Participants ◽  
The Relationship

The purpose of this study was to investigate the mediating role of social support and social connectedness between hope and resilience in adolescents. A total of 413 high school students (57.1% girls; M= 17.31, SD= 1.61) participated in the study. Participants completed the Children’s Hope Scale (CHS), Brief Resilience Scale (BRS), Brief Perceived Social Support Questionnaire (BPSSQ), and Social Connectedness Scale (SCS). The results showed that there was a positive significant correlation between social support, resilience, social connectedness, and hope. In addition, according to the gender variable, it is seen that the resilience and hope scores of the boys are significantly higher than the girls. On the other hand, no significant difference was found in social connectedness and social support in terms of gender. The results mediation analysis showed that hope significantly and positively predicted social connectedness, social support, and resilience. Also, social connectedness positively and significantly predicted social support, and social support was a significant predictor of resilience. Most importantly, social support and social connectedness acted as mediating roles in the relationship between hope and resilience. These results suggest that social connectedness and social support are two important sources in developing resilience. This has important implications for research and practice.

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