Comparative Osseous and Soft Tissue Morphology following Cleft Lip Repair

2008 ◽  
Vol 45 (5) ◽  
pp. 511-517 ◽  
Author(s):  
Lynn M. Seidenstricker-Kink ◽  
Devra B. Becker ◽  
Daniel P. Govier ◽  
Valerie B. DeLeon ◽  
Lun-Jou Lo ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Soft Tissue ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Three Dimensional ◽  
Processing System ◽  
Distance Matrix ◽  
Euclidean Distance Matrix ◽  
Computed Tomography Scans ◽  
Nasal Region

Objective: To quantify comparative improvement between osseous and soft tissue asymmetry following primary lip repair. Design: Retrospective analysis of preoperative and postoperative computed tomography scans of infants with unilateral cleft lip and palate. Sixteen soft tissue landmarks were placed using an exploratory two-/three-dimensional image processing system and compared for asymmetry. Patients: Computed tomography scans were obtained on 26 patients (13 boys, 13 girls) of Chinese ethnicity (mean age  =  0.25 years) prior to Millard lip repair. Nineteen of these contributed to follow-up comparative studies prior to palatoplasty at a mean age of 0.92 years. There were 18 left-sided and eight right-sided clefts. Main Outcome Measure: Euclidean distance matrix asymmetry analysis was used to determine the amount of soft tissue asymmetry pre- and postlip repair. Similar analyses of the same scans were performed for 41 osseous landmarks. Results: Soft tissue landmarks had 36/39 (92%) preoperative and 13/39 (33%) postoperative asymmetric pairs. Osseous distances demonstrated 77/125 (61%) asymmetric pairs preoperatively and 60/125 (48%) postoperatively. Soft tissue and osseous distances of the lip region demonstrated 32% and 39% postoperative asymmetry, respectively. Soft tissue and osseous distances of the nasal region demonstrated 52% and 72% postoperative asymmetry, respectively. Soft tissue and osseous distances of the facial landmarks demonstrated 24% and 34% postoperative asymmetry, respectively. Conclusions: Primary lip repair appears to effect gains in symmetry in soft tissue and provides sufficient molding forces to cause correlating symmetry changes in underlying osseous structures.

The Hyoid Bone in Malay Infants with Cleft Lip and Palate

2006 ◽  
Vol 43 (5) ◽  
pp. 532-538 ◽  
Author(s):  
Zainul A. Rajion ◽  
Grant C. Townsend ◽  
David J. Netherway ◽  
Peter J. Anderson ◽  
Toby Hughes ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cervical Spine ◽  
Software Package ◽  
Hyoid Bone ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Three Dimensional ◽  
Cross Sectional ◽  
Computed Tomography Scans ◽  
Age Range

Objective: To compare morphological and positional variations of the hyoid bone in unoperated infants with cleft lip and palate (CL/P) with those in noncleft infants. Design: Retrospective, cross sectional. Patients and Methods: Three-dimensional computed tomography scans were obtained from 29 unoperated CL/P infants of Malay origin aged between 0 and 12 months and from 12 noncleft infants in the same age range. Observations were made and measurements were obtained with a software package developed at the Australian Craniofacial Unit. The sizes of the hyoid bones and the position of the hyoid body and epiglottis in relation to the cervical spine were measured. Anatomical anomalies of the hyoid and prevalence of aspiration pneumonia were also documented. Results: The hyoid bones and epiglottis were found to be located more inferiorly in CL/P infants compared with the noncleft infants. Also, 17% (5/29) of the CL/P infants had nonossified hyoid bodies. Conclusion: The results suggest that there are differences in the location and genesis of the hyoid bone in infants with CL/P that warrant further investigation.

Adults With Unilateral Cleft Lip and Palate Present Reduced Internal Nasal Volumes: Findings of a Three-Dimensional Morphometric Assessment in Cone-Beam Computed Tomography Scans

2020 ◽  
Vol 32 (1) ◽  
pp. e15-e19
Author(s):  
Renan Jhordan Mettelziefen dos Inocentes ◽  
Maria Noel Marzano-Rodrigues ◽  
Guilherme Gonçalves de Espíndola ◽  
Michele García-Usó ◽  
Marília Sayako Yatabe-Ioshida ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cone Beam Computed Tomography ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Three Dimensional ◽  
Cone Beam ◽  
Computed Tomography Scans ◽  
Morphometric Assessment

A Three-Dimensional Computed Tomographic Analysis of the Cervical Spine in Unoperated Infants with Cleft Lip and Palate

2006 ◽  
Vol 43 (5) ◽  
pp. 513-518 ◽  
Author(s):  
Zainul A. Rajion ◽  
Grant C. Townsend ◽  
David J. Netherway ◽  
Peter J. Anderson ◽  
Asilah Yusof ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cervical Spine ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Three Dimensional ◽  
Abnormal Development ◽  
Posterior Arch ◽  
Cross Sectional ◽  
Computed Tomography Scans ◽  
Vertebral Bodies

Objective: To investigate anatomical variations and abnormalities of cervical spine morphology in unoperated infants with cleft lip and palate. Design: Retrospective cross-sectional investigation of infants born with nonsyndromic cleft lip and palate using computed tomography scans acquired for investigation of a spectrum of clinical conditions. Setting: Computed tomography scan data were obtained from 29 unoperated cleft lip and palate infants and 12 noncleft infants of Malay origin, ages 0 to 12 months. Methods: Observational study of cervical spine computed tomography scans. Heights of cervical vertebral bodies (C2-C7) and intervertebral spaces were measured from landmarks identified from computed tomography reformats and three-dimensional computed tomography reconstructions. Linear modeling of heights and spaces, with age as a covariate, was undertaken to identify differences between the samples. Results: Anomalous features observed in the cleft lip and palate sample included short posterior arch of C1 (2/29), abnormal development of the anterior arch of C1 (2/29), and fusions of the posterior arch of C2 and C3 (2/29). No anomalies of the cervical spine were observed in the noncleft sample. Although the heights of three cervical vertebral bodies were significantly smaller and two intervertebral spaces were significantly larger in infants with cleft lip and palate compared with noncleft infants (p < .05), overall length of the cervical spine did not differ significantly between the samples. Conclusion: There was evidence for subtle upper spinal anomalies in the infant cleft lip and palate population. Our finding of reduced size of some cervical vertebral bodies may reflect delayed upper spinal development in infants with cleft lip and palate.

A Quantitative Three-Dimensional Assessment of Abnormal Variations in Facial Soft Tissues of Adult Patients with Cleft Lip and Palate

2003 ◽  
Vol 40 (5) ◽  
pp. 544-549 ◽  
Author(s):  
Virgilio F. Ferrario ◽  
Chiarella Sforza ◽  
Claudia Dellavia ◽  
Gianluca M. Tartaglia ◽  
Davide Sozzi ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Cleft Lip ◽  
Soft Tissues ◽  
Cleft Lip And Palate ◽  
Three Dimensional ◽  
Z Score ◽  
Soft Tissue Profile ◽  
Variability Index ◽  
The Mean ◽  
Facial Soft Tissues

Objective To supply quantitative information about the facial soft tissues of adult operated patients with cleft lip and palate (CLP). Design, Setting, and Patients The three-dimensional coordinates of soft tissue facial landmarks were obtained using an electromagnetic digitizer in 18 Caucasian patients with CLP (11 males and 7 females aged 19 to 27 years) and 162 healthy controls (73 females and 89 males aged 18 to 30 years). From the landmarks, 15 facial dimensions and two angles were calculated. Data were compared with those collected in healthy individuals by computing z-scores. Two summary anthropometric measurements for quantifying craniofacial variations were assessed in both the patients and reference subjects: the mean z-score (an index of overall facial size), and its SD, called the craniofacial variability index (an index of facial harmony). Results In treated patients with CLP, facial size was somewhat smaller than in normal individuals, but in all occasions the mean z-score fell inside the normal interval (mean ± 2 SD). Almost all patients had a craniofacial variability index larger than the normal interval, indicating a global disharmonious appearance. Overall, in patients pronasale, subnasale, and pogonion were more posterior, the nose was shorter and larger, the face was narrower, and the soft tissue profile and upper lip were flatter than in the reference population. Conclusions The facial soft tissue structures of adult operated patients with CLP differed from those of normal controls of the same age, sex, and ethnic group. In this patient group, surgical corrections of CLP failed to provide a completely harmonious appearance, even if the deviations from the reference were limited. Further analyses of larger groups of patients are needed.

Comparison of Numeric Techniques in the Analysis of Cleft Palate Dental Arch Form Change

1997 ◽  
Vol 34 (4) ◽  
pp. 281-291 ◽  
Author(s):  
Mona E. McAlarney ◽  
Wei-Kwang Chiu
Keyword(s):  
Finite Element ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Distance Matrix ◽  
Matrix Analysis ◽  
Dental Arch ◽  
Scaling Analysis ◽  
Euclidean Distance Matrix ◽  
Arch Form ◽  
Form Change

Objective: Quantitative descriptions of form (size and shape) changes are significant to the understanding of the development, treatment planning, and prognosis of patients born with cleft lip and palate. This study compared the results of traditional dental arch form change measurements, such as width, depth, perimeter, and area, with four numeric methods: finite element scaling analysis, macroelement method, Euclidean distance matrix analysis, and conventional least-squares and resistant-fit theta rho Procrustes analyses. Design: Using tooth cusp landmarks on maxillary study casts, form change measurements of a male with complete bilateral cleft lip and palate at ages 2, 5, and 6 years were made comparing each age to the next older. Results and Conclusions: With the exception of the 2- to 5-year resistant-fit analysis, all numeric methods: 1) provide comparable results, 2) provide more detailed descriptions than do traditional methods, and 3) provide results that correlate well with the reported effects of increased lip pressure due to lip closure surgery. The use of finite-element scaling analysis on study casts is somewhat limited since: 1) there is more than one solution at teeth shared by many finite elements, 2) gross averaging of form change occurs within triangular elements, and 3) solutions can vary with the choice of element location. The use of the macroelement method circumvented the above finite element limitations with out compromising finite-element advantages. Procrustes results vary with the chosen superposition algorithm. The choice of the most appropriate Procrustes method required some a priori knowledge of form difference. The large number of results obtained by Euclidean distance matrix analysis and the nongraphic presentation of these results hamper quick interpretation but may be best suited for definitive statistical analysis. The graphic representation of both the magnitude and direction of: 1) landmark displacement in the Procrustes analyses (once size difference is eliminated), and 2) the rate of form change in the macroelement method provide an intuitive appreciation of how and where the casts differ.

scholarly journals Three-Dimensional Soft-Tissue Evaluation in Patients with Cleft Lip and Palate

2018 ◽  
Vol 24 ◽  
pp. 8608-8620 ◽  
Author(s):  
Selin Alpagan Ozdemir ◽  
Elçin Esenlik
Keyword(s):  
Soft Tissue ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Three Dimensional
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