scholarly journals Potential Role of Coregistered Photoacoustic and Ultrasound Imaging in Ovarian Cancer Detection and Characterization

2011 ◽  
Vol 4 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Andres Aguirre ◽  
Yasaman Ardeshirpour ◽  
Mary M. Sanders ◽  
Molly Brewer ◽  
Quing Zhu
Keyword(s):  
Ovarian Cancer ◽  
Ultrasound Imaging ◽  
Cancer Detection ◽  
Potential Role

scholarly journals Potential role of a hybrid intraoperative probe based on OCT and positron detection for ovarian cancer detection and characterization

2011 ◽  
Vol 2 (7) ◽  
pp. 1918 ◽  
Author(s):  
Yi Yang ◽  
Nrusingh C. Biswal ◽  
Tianheng Wang ◽  
Patrick D. Kumavor ◽  
Mozafareddin Karimeddini ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Detection ◽  
Potential Role

scholarly journals Correction: Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
Author(s):  
Carine Bossard ◽  
Muriel Busson ◽  
David Vindrieux ◽  
Françoise Gaudin ◽  
Véronique Machelon ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Estrogen Receptor ◽  
Tumor Suppressor ◽  
Epithelial Ovarian Cancer ◽  
Potential Role ◽  
Estrogen Receptor Beta ◽  
Receptor Beta ◽  
Correction Potential

scholarly journals Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

PLoS ONE ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. e44787 ◽  
Author(s):  
Carine Bossard ◽  
Muriel Busson ◽  
David Vindrieux ◽  
Françoise Gaudin ◽  
Véronique Machelon ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Estrogen Receptor ◽  
Tumor Suppressor ◽  
Epithelial Ovarian Cancer ◽  
Potential Role ◽  
Estrogen Receptor Beta ◽  
Receptor Beta

scholarly journals Potential Role of HE4 in Multimodal Screening for Epithelial Ovarian Cancer

2011 ◽  
Vol 103 (21) ◽  
pp. 1630-1634 ◽  
Author(s):  
N. Urban ◽  
J. D. Thorpe ◽  
L. A. Bergan ◽  
R. M. Forrest ◽  
A. V. Kampani ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Potential Role

scholarly journals The potential role of miRNAs and exosomes in chemotherapy in ovarian cancer

2018 ◽  
Vol 25 (12) ◽  
pp. R663-R685 ◽  
Author(s):  
Mona Alharbi ◽  
Felipe Zuñiga ◽  
Omar Elfeky ◽  
Dominic Guanzon ◽  
Andrew Lai ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Disease Progression ◽  
Potential Role ◽  
Chemotherapy Resistance ◽  
Predictive Biomarker ◽  
Response To Therapy ◽  
Target Cells ◽  
Repair Mechanisms ◽  
Drug Efflux Pumps

Chemoresistance is one of the major obstacles in the treatment of cancer patients. It poses a fundamental challenge to the effectiveness of chemotherapy and is often linked to relapse in patients. Chemoresistant cells can be identified in different types of cancers; however, ovarian cancer has one of the highest rates of chemoresistance-related relapse (50% of patients within 5 years). Resistance in cells can either develop through prolonged cycles of treatment or through intrinsic pathways. Mechanistically, the problem of drug resistance is complex mainly because numerous factors are involved, such as overexpression of drug efflux pumps, drug inactivation, DNA repair mechanisms and alterations to and/or mutations in the drug target. Additionally, there is strong evidence that circulating miRNAs participate in the development of chemoresistance. Recently, miRNAs have been identified in exosomes, where they are encapsulated and hence protected from degradation. These miRNAs within exosomes (exo-miRNAs) can regulate the gene expression of target cells both locally and systemically. Exo-miRNAs play an important role in disease progression and can potentially facilitate chemoresistance in cancer cells. In addition, and from a diagnostic perspective, exo-miRNAs profiles may contribute to the development of predictive models to identify responder and non-responder chemotherapy. Such model may also be used for monitoring treatment response and disease progression. Exo-miRNAs may ultimately serve as both a predictive biomarker for cancer response to therapy and as a prognostic marker for the development of chemotherapy resistance. Therefore, this review examines the potential role of exo-miRNAs in chemotherapy in ovarian cancer.

scholarly journals Potential role of miR-9 and miR-223 in recurrent ovarian cancer

2008 ◽  
Vol 7 (1) ◽  
pp. 35 ◽  
Author(s):  
Alexandros Laios ◽  
Sharon O'Toole ◽  
Richard Flavin ◽  
Cara Martin ◽  
Lynn Kelly ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Potential Role ◽  
Recurrent Ovarian Cancer

Abstract 3904: Potential role of WNT7A in ovarian cancer

2010 ◽  
Author(s):  
Kanako Hayashi ◽  
Shin Yoshioka ◽  
Sophia Ran ◽  
Mary McAsey ◽  
James A. Maclean
Keyword(s):  
Ovarian Cancer ◽  
Potential Role

The potential role of anibamine, a natural product CCR5 antagonist, and its analogues as leads toward development of anti-ovarian cancer agents

2012 ◽  
Vol 22 (15) ◽  
pp. 5093-5097 ◽  
Author(s):  
Yan Zhang ◽  
Christopher K. Arnatt ◽  
Feng Zhang ◽  
Jiannan Wang ◽  
Kendra M. Haney ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Natural Product ◽  
Potential Role ◽  
Ccr5 Antagonist
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