scholarly journals Brain Tumor Stem-Like Cells Identified by Neural Stem Cell Marker CD15

2009 ◽  
Vol 2 (4) ◽  
pp. 247-257 ◽  
Author(s):  
Xing-gang Mao ◽  
Xiang Zhang ◽  
Xiao-yan Xue ◽  
Geng Guo ◽  
Peng Wang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Brain Tumor ◽  
Neural Stem Cell ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Neural Stem Cell Marker

Abstract 3403: The neural stem cell marker GLAST, is involved in proliferation and invasion by glutamate release

2011 ◽  
Author(s):  
Serena Pellegatta ◽  
Federica Pisati ◽  
Gabriele Cantini ◽  
Véronique Frattini ◽  
Pietro Luigi Poliani ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Glutamate Release ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Neural Stem Cell Marker ◽  
Proliferation And Invasion

Expression of the Neural Stem Cell Marker Msi-1 in the Rat Telencephalon

2012 ◽  
Vol 42 (6) ◽  
pp. 617-619
Author(s):  
O. V. Kirik ◽  
O. S. Alekseeva ◽  
D. E. Korzhevskii
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Neural Stem Cell Marker

scholarly journals The neural stem-cell marker CD24 is specifically upregulated in IDH-mutant glioma

2020 ◽  
Vol 13 (10) ◽  
pp. 100819
Author(s):  
Patricia D.B. Tiburcio ◽  
Mary C. Locke ◽  
Srividya Bhaskara ◽  
Mahesh B. Chandrasekharan ◽  
L. Eric Huang
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Neural Stem Cell Marker

POTENTIAL ROLE FOR NESTIN, A NEURAL STEM CELL MARKER, IN THE PATHOPHYSIOLOGY OF INJURY AND REPAIR OF THE CAVERNOUS NERVE

2009 ◽  
Vol 181 (4S) ◽  
pp. 241-241
Author(s):  
Trinity J Bivalacqua ◽  
Travis D Strong ◽  
Edward M Schaeffer ◽  
Christian P Pavlovich ◽  
Hunter C Champion ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Potential Role ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Cavernous Nerve ◽  
Injury And Repair ◽  
Neural Stem Cell Marker

scholarly journals A novel population of myeloid cells responding to coxsackievirus infection in the neonatal CNS nxpress a neural stem cell marker

2008 ◽  
Vol 2 (Suppl 1) ◽  
pp. P65
Author(s):  
Jenna M Tabor-Godwin ◽  
Chelsea M Ruller ◽  
Kelly S Doran ◽  
Christopher T Cornell ◽  
Naili An ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Myeloid Cells ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Neural Stem Cell Marker

scholarly journals Expression of Angiogenic Factors in Invasive Retinoblastoma Tumors Is Associated With Increase in Tumor Cells Expressing Stem Cell Marker Sox2

2015 ◽  
Vol 139 (12) ◽  
pp. 1531-1538 ◽  
Author(s):  
Jesús R. Garcia ◽  
Dan S. Gombos ◽  
Claudia M. Prospero ◽  
Aravindh Ganapathy ◽  
Rebecca L. Penland ◽  
...  
Keyword(s):  
Stem Cell ◽  
High Risk ◽  
Tumor Cells ◽  
Neural Stem Cell ◽  
Angiogenic Factors ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Angiogenic Growth Factors ◽  
Tumor Invasiveness ◽  
Neural Stem Cell Marker

Context Progression of retinoblastoma is associated with increased tumor angiogenesis. However, a clear relationship between the expression of angiogenic markers in specific regions of the tumor and tumor progression has not been established. This study investigates the association between angiogenic factors in retinoblastomas with choroidal and/or optic nerve invasion (high-risk/invasive retinoblastoma) and expression of Sox2, a stem cell marker. Objective To investigate the association between the expression of angiogenic factors and markers of tumor invasiveness, such as the stem cell marker Sox2, in retinoblastoma tissues. Design Immunohistochemistry was used to evaluate coexpression of the angiogenic growth factors vascular endothelial growth factor A (VEGF-A), VEGF receptor 2 (VEGFR-2), and endoglin (CD105); markers of glial differentiation (vimentin and glial fibrillary acidic protein); and a neural stem cell marker (Sox2). Expression was assessed in nonneoplastic and neoplastic ocular tissues collected from enucleated eyes of patients with retinoblastoma. During qualitative data interpretation, evaluating pathologists were masked to patient grouping. Results Expression of VEGF-A and VEGFR-2 in noninvasive (non–high-risk feature) retinoblastoma tumors was lower than in the invasive, or high-risk feature tumors. Moreover, our data indicate that the tumor cells, and not the surrounding stroma, secrete VEGF-A and that angiogenesis is mostly localized to the iris. Finally, our data showed that the expression of the neural stem cell marker Sox2 is associated with eyes with increased VEGF-A expression and tumor invasiveness. Conclusions Increased expression of angiogenic factors, with a concomitant increase in expression of the stem cell marker Sox2 observed in retinoblastoma tissues, may partially explain the aggressiveness of these tumors. The complex interaction of angiogenic and stem cell–related pathways in these tumors, especially in high-risk feature retinoblastoma, suggests that targeting tumor cells capable of secreting vasculogenic factors, as well as proangiogenic genes and signaling pathways, may be necessary for development of effective antimetastatic retinoblastoma drugs.

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