Zolpidem Addiction in a Pregnant Woman with a History of Second-Trimester Bleeding

2007 ◽  
Vol 27 (2) ◽  
pp. 306-308 ◽  
Author(s):  
Jennifer P Askew
Keyword(s):  
Pregnant Woman ◽  
Second Trimester ◽  
History Of

Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?

2017 ◽  
Vol 68 (10) ◽  
pp. 2234-2236
Author(s):  
Dan Navolan ◽  
Florin Birsasteanu ◽  
Adrian Carabineanu ◽  
Octavian Cretu ◽  
Diana Liana Badiu ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Cigarette Smoke ◽  
Chorionic Gonadotropin ◽  
Reference Values ◽  
Biochemical Markers ◽  
Smoking Status ◽  
Active Smoking ◽  
Second Trimester ◽  
Harmful Effects

Cigarette smoke contains over 7000 different substances some of them exerting harmful effects on embryo and pregnant woman. Nowadays 15 % of adult people and around 10-15% of pregnant women smoke. Previous studies showed that cigarette smoke compounds could exert pharmacodinamic effects and influence some of the second trimester biochemical markers concentration. Therefore there is a need to adjust the reference values of second trimester markers depending of the smoker status. The aim of our study was to analyse which of the markers are influenced by smoking and whether the software used to calculate the risk for aneuploidies is able to counterbalance this influence. Alpha-fetoprotein (AFP), chorionic gonadotropin hormone (hCG) and free estriol (uE3) values were measured in second trimester sera of 1242 pregnant women: 1089 non-smokers and 153 smokers. Only hCG second trimester values were influenced by smoking whereas AFP and uE3 values were not. The correction of medians according to the smoking status was able to counterbalance this effect.

scholarly journals To Give or Not to Give: RhD Immunoglobulin for an RHD*39 Pregnant Woman with Sickle Cell Disease

2021 ◽  
pp. 1-5
Author(s):  
Justin E. Juskewitch ◽  
Craig D. Tauscher ◽  
Sheila K. Moldenhauer ◽  
Jennifer E. Schieber ◽  
Eapen K. Jacob ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Pregnancy Termination ◽  
Acute Chest Syndrome ◽  
Cell Disease ◽  
Childbearing Age ◽  
Procedural Complications ◽  
History Of ◽  
Chronic Hemolysis

Introduction: Patients with sickle cell disease (SCD) have repeated episodes of red blood cell (RBC) sickling and microvascular occlusion that manifest as pain crises, acute chest syndrome, and chronic hemolysis. These clinical sequelae usually increase during pregnancy. Given the racial distribution of SCD, patients with SCD are also more likely to have rarer RBC antigen genotypes than RBC donor populations. We present the management and clinical outcome of a 21-year-old pregnant woman with SCD and an RHD*39 (RhD[S103P], G-negative) variant. Case Presentation: Ms. S is B positive with a reported history of anti-D, anti-C, and anti-E alloantibodies (anti-G testing unknown). Genetic testing revealed both an RHD*39 and homozygous partial RHCE*ceVS.02 genotype. Absorption/elution testing confirmed the presence of anti-G, anti-C, and anti-E alloantibodies but could not definitively determine the presence/absence of an anti-D alloantibody. Ms. S desired to undergo elective pregnancy termination and the need for postprocedural RhD immunoglobulin (RhIG) was posed. Given that only the G antigen site is changed in an RHD*39 genotype and the potential risk of RhIG triggering a hyperhemolytic episode in an SCD patient, RhIG was not administered. There were no procedural complications. Follow-up testing at 10 weeks showed no increase in RBC alloantibody strength. Discussion/Conclusion: Ms. S represents a rare RHD*39 and partial RHCE*ceVS.02 genotype which did not further alloimmunize in the absence of RhIG administration. Her case also highlights the importance of routine anti-G alloantibody testing in women of childbearing age with apparent anti-D and anti-C alloantibodies.

A Pregnant Woman with Type 2 Diabetes Unintentionally Exposed to Metformin and Voglibose until the Second Trimester of Pregnancy: A Case Report

2016 ◽  
Vol 17 (4) ◽  
pp. 277
Author(s):  
Yeo Un Kim ◽  
Jae Hoon Kwak ◽  
Se Hwan Yeo ◽  
Seong Su Moon ◽  
Young Sil Lee
Keyword(s):  
Type 2 Diabetes ◽  
Case Report ◽  
Pregnant Woman ◽  
Second Trimester

The Natural History of Trisomy 21: Outcome Data from a Large Tertiary Referral Centre

2021 ◽  
pp. 1-7
Author(s):  
Clare O’Connor ◽  
Rebecca Moore ◽  
Peter McParland ◽  
Heather Hughes ◽  
Barbara Cathcart ◽  
...  
Keyword(s):  
Trisomy 21 ◽  
Pregnancy Loss ◽  
Loss Rate ◽  
Outcome Data ◽  
Second Trimester ◽  
Referral Centre ◽  
Tertiary Referral ◽  
Tertiary Referral Centre ◽  
History Of ◽  
Baseline Demographic

<b><i>Objective:</i></b> The aim of the study was to prospectively gather data on pregnancy outcomes of prenatally diagnosed trisomy 21 (T21) in a large tertiary referral centre. <b><i>Methods:</i></b> Data were gathered prospectively in a large tertiary referral centre over 5 years from 2013 to 2017 inclusively. Baseline demographic and pregnancy outcome data were recorded on an anonymized computerized database. <b><i>Results:</i></b> There were 1,836 congenital anomalies diagnosed in the study period including 8.9% (<i>n</i> = 165) cases of T21. 79% (<i>n</i> = 131) were age 35 or older at diagnosis. 79/113 (69.9%) women chose a termination of pregnancy (TOP) following a diagnosis of T21. Amongst pregnancies that continued, there were 4 second-trimester miscarriages (4/34, 11.7%), 9 stillbirths (9/34, 26.4%), and 1 neonatal death, giving an overall pregnancy and neonatal loss rate of 14/34 (41.1%). <b><i>Conclusion:</i></b> The risk of foetal loss in prenatally diagnosed T21 is high at 38% with an overall pregnancy loss rate of 41.1%. This information may be of benefit when counselling couples who are faced with a diagnosis of T21 particularly in the context of limited access to TOP.

scholarly journals When Death Is Not the End: Continuing Somatic Care during Postmortem Pregnancy

2019 ◽  
Vol 86 (4) ◽  
pp. 275-282
Author(s):  
Jennifer J. Barr
Keyword(s):  
Pregnant Woman ◽  
Brain Death ◽  
Artificial Ventilation ◽  
Second Trimester ◽  
Brain Dead

Brain death during the second trimester of pregnancy creates a unique situation in which the mother is deceased, but life of the developing fetus still depends on somatic functions in the mother’s body. In this article, I show that when a pregnant woman becomes brain dead during the second trimester, it is morally licit, though not morally obligatory, to continue somatic support while the fetus develops. The interventions on the mother’s body are justified for the life of the fetus, especially in light of the unique mother–child dyad and the responsibilities the mother has for her child. However, this therapy is not frequently employed, and its success is unpredictable. In many cases, the expense and uncertain nature of the therapy may make it disproportionate. In such cases, somatic support of the mother’s body may be discontinued. Summary: When brain death is diagnosed during pregnancy, it is a challenging decision whether to use artificial ventilation and other heroic measures to support the developing fetus. This paper demonstrates that while these interventions are acceptable, they are not obligatory.

scholarly journals Acute Hemoperitoneum after Administration of Prostaglandin E2for Induction of Labour

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Zhenyu Zhang ◽  
Jiangyan Lou
Keyword(s):  
Laparoscopic Surgery ◽  
Pregnant Woman ◽  
Pregnant Women ◽  
Stage Iv ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Prostaglandin E ◽  
History Of

Prostaglandin E2is widely used in obstetrics and is thought to be relatively safe for cervical ripening and induction of labour. Here we present a case in which acute hemoperitoneum was observed after administration of prostaglandin E2in a pregnant woman. The patient had a history of endometriosis, and a severe pelvic adhesion (ASRM stage IV) was found during her last laparoscopic surgery 3 years previously. In cases with endometriosis, use of prostaglandin E2for induction of labour in pregnant women must be done cautiously.

A Pregnant Woman with Cranial Aneurysm Rupture in the Second Trimester of Pregnancy

2020 ◽  
Vol 140 ◽  
pp. 229-232
Author(s):  
Emine Karabuk ◽  
Pinar Kadirogullari ◽  
Talat Umut Kutlu Dilek ◽  
Enes Ozluk ◽  
Gulsah Ozturk
Keyword(s):  
Pregnant Woman ◽  
Aneurysm Rupture ◽  
Second Trimester

scholarly journals Management of Locally Advanced Esthesioneuroblastoma in a Pregnant Woman

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Inês Maria Guerreiro ◽  
Cláudia Vieira ◽  
André Soares ◽  
António Braga ◽  
Manuel Jácome ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Nasal Obstruction ◽  
Standard Treatment ◽  
Combined Treatment ◽  
Locally Advanced ◽  
Cervical Lymphadenopathy ◽  
Complete Response ◽  
High Grade ◽  
History Of ◽  
Worse Prognosis

Esthesioneuroblastoma (ENB) is a rare malignant tumor that commonly develops in the upper nasal cavity. Standard treatment is not established, especially in locally advanced disease which portends the worse prognosis. Hereby, we report a case of a 27-year-old, 23-week pregnant woman, with a 2-month history of progressively growing right cervical lymphadenopathy, nasal obstruction, anosmia, frequent episodes of epistaxis, and right frontal headache. Imagiological evaluation revealed a lesion with 7×5,2×3,2 cm in the nasal fossae with extension to the ethmoidal complex and right olfactive fend and invasion of the endocranial compartment associated with lymphadenopathy. The biopsy revealed a high-grade EBN. Neoadjuvant chemotherapy with cisplatin and etoposide was administrated during pregnancy and continued after delivery up to 6 cycles of treatment with partial response. Radiotherapy followed, with complete response. This case report is intended to highlight that a high grade of suspicion should be kept in the presence of nonspecific symptoms of nasal obstruction, anosmia, facial pain, and/or headache and focus that chemotherapy is an important component of a combined-treatment modality for locally advanced ENB that can be used during pregnancy in a lifesaving situation.

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