scholarly journals Antimicrobial Photodynamic Therapy in the Endodontic Treatment of Deciduous Teeth: In Vivo Pilot Study

Author(s):  
Maria Luiza da Matta Felisberto Fernandes ◽  
Caroline Andrade Maia ◽  
Alice Machado Carvalho Santos ◽  
Camila Rocha Vilela ◽  
Felipe Ribeiro Araujo ◽  
...  
2018 ◽  
Vol 94 (4) ◽  
pp. 760-764 ◽  
Author(s):  
Camila Basilio Okamoto ◽  
Lara Jansiski Motta ◽  
Renato Araujo Prates ◽  
Ana Carolina Costa da Mota ◽  
Marcela Leticia Leal Gonçalves ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
G. C. Santin ◽  
D. S. B. Oliveira ◽  
R. Galo ◽  
M. C. Borsatto ◽  
S. A. M. Corona

Background. The aim of this study was to perform a systematic review of the literature on the efficacy of antimicrobial photodynamic therapy (PDTa) on cariogenic dental biofilm.Types of Studies Reviewed. Studiesin vivo,in vitro, andin situwere included. Articles that did not address PDTa, those that did not involve cariogenic biofilm, those that used microorganisms in the plankton phase, and reviews were excluded. Data extraction and quality assessments were performed independently by two raters using a scale.Results. Two hundred forty articles were retrieved; only seventeen of them met the eligibility criteria and were analyzed in the present review. Considerable variability was found regarding the methodologies and application protocols for antimicrobial PDTa. Two articles reported unfavorable results.Practical Implications. The present systematic review does not allow drawing any concrete conclusions regarding the efficacy of antimicrobial PDTa, although this method seems to be a promising option.


2012 ◽  
Author(s):  
João Alves dos Reis Júnior ◽  
Patrícia Nascimento de Assis ◽  
Garde^nia Matos Paraguassú ◽  
Isabele Cardoso Vieira de de Castro ◽  
Renan Ferreira Trindade ◽  
...  

2018 ◽  
Vol 11 (6) ◽  
pp. 510-512
Author(s):  
Fernanda Hecksher ◽  
Bruno Vidigal ◽  
Patricia Coelho ◽  
Diassanam Otoni ◽  
Christiano Alvarenga ◽  
...  

2019 ◽  
Vol 12 (3) ◽  
pp. 140 ◽  
Author(s):  
Karem Janeth Rimachi Hidalgo ◽  
Juliana Cabrini Carmello ◽  
Cláudia Carolina Jordão ◽  
Paula Aboud Barbugli ◽  
Carlos Alberto de Sousa Costa ◽  
...  

Background: It has been demonstrated that azole-resistant strains of Candida albicans have a greater resistance to antimicrobial photodynamic therapy (aPDT) when compared to their more susceptible counterparts. For this reason, the present study evaluated the efficacy of aPDT, together with nystatin (NYS), in the treatment of oral candidiasis in vivo. Methods: Mice were infected with fluconazole-resistant C. albicans (ATCC 96901). To perform the combined therapy, aPDT, mediated by Photodithazine (PDZ) and LED light, was used together with NYS. The efficacy of the treatments was evaluated by microbiological, macroscopic, histopathological and Confocal Scanning Laser Microscopy analyses of the lesions. The expression of p21 and p53, proteins associated with cell death, from the tongues of mice, was also performed. Results: The combined therapy reduced the fungal viability by around 2.6 log10 and decreased the oral lesions and the inflammatory reaction. Additionally, it stimulated the production of p53 and p21. Conclusions: The combined therapy is a promising alternative treatment for oral candidiasis induced by C. albicans resistant to fluconazole.


2008 ◽  
Vol 24 (4) ◽  
pp. 521-526 ◽  
Author(s):  
Sérgio Luiz Pinheiro ◽  
Ada Almeida Schenka ◽  
Alexandre Alves Neto ◽  
Cristiane Pedroso de Souza ◽  
Helena Margarita Hiar Rodriguez ◽  
...  

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