scholarly journals Sugar, fat, saturated and trans fatty acid contents in Iranian cereal-based baked products

2021 ◽  
Author(s):  
Zahra HADIAN ◽  
Amin MOUSAVI KHANEGHAH
Keyword(s):  
Fatty Acid ◽  
Trans Fatty Acid ◽  
Baked Products

scholarly journals Trans Fatty Acid Intake Induces Intestinal Inflammation and Impaired Glucose Tolerance

2021 ◽  
Vol 12 ◽  
Author(s):  
Takuro Okamura ◽  
Yoshitaka Hashimoto ◽  
Saori Majima ◽  
Takafumi Senmaru ◽  
Emi Ushigome ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Trans Fatty Acid ◽  
Trans Fatty Acids ◽  
Intestinal Inflammation ◽  
Fatty Acid Intake ◽  
Acid Intake ◽  
Trans Fatty Acid Intake ◽  
High Sucrose Diet ◽  
High Sucrose

Background and AimsMany nutritional and epidemiological studies have shown that high consumption of trans fatty acids can cause several adverse effects on human health, including cardiovascular disease, diabetes, and cancer. In the present study, we investigated the effect of trans fatty acids on innate immunity in the gut by observing mice fed with a diet high in trans fatty acids, which have been reported to cause dysbiosis.MethodsWe used C57BL6/J mice and fed them with normal diet (ND) or high-fat, high-sucrose diet (HFHSD) or high-trans fatty acid, high-sucrose diet (HTHSD) for 12 weeks. 16S rRNA gene sequencing was performed on the mice stool samples, in addition to flow cytometry, real-time PCR, and lipidomics analysis of the mice serum and liver samples. RAW264.7 cells were used for the in vitro studies.ResultsMice fed with HTHSD displayed significantly higher blood glucose levels and advanced fatty liver and intestinal inflammation, as compared to mice fed with HFHSD. Furthermore, compared to mice fed with HFHSD, mice fed with HTHSD displayed a significant elevation in the expression of CD36 in the small intestine, along with a reduction in the expression of IL-22. Furthermore, there was a significant increase in the populations of ILC1s and T-bet-positive ILC3s in the lamina propria in mice fed with HTHSD. Finally, the relative abundance of the family Desulfovibrionaceae, which belongs to the phylum Proteobacteria, was significantly higher in mice fed with HFHSD or HTHSD, than in mice fed with ND; between the HFHSD and HTHSD groups, the abundance was slightly higher in the HTHSD group.ConclusionsThis study revealed that compared to saturated fatty acid intake, trans fatty acid intake significantly exacerbated metabolic diseases such as diabetes and fatty liver.

scholarly journals Is Trans Fatty Acid Still an Issue for Policy Makers in Iran? A Technical Report

2018 ◽  
Vol 5 (2) ◽  
pp. 47-51 ◽  
Author(s):  
Zahra Saghafi ◽  
Azizollaah Zargaraan ◽  
Mahnaz Tabibiazar ◽  
Hedayat Hosseini ◽  
◽  
...  
Keyword(s):  
Fatty Acid ◽  
Trans Fatty Acid ◽  
Policy Makers ◽  
Technical Report
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