scholarly journals Hypocholesterolemic effect of designer yogurts fortified with omega fatty acids and dietary fibers in hypercholesterolemic subjects

2021 ◽  
Author(s):  
Nazir AHMAD ◽  
Umair SHABBIR ◽  
Aysha SAMEEN ◽  
Muhammad Faisal MANZOOR ◽  
Muhammad Haseeb AHMAD ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Hypocholesterolemic Effect ◽  
Dietary Fibers ◽  
Omega Fatty Acids ◽  
Hypercholesterolemic Subjects

scholarly journals Health lipid indices and physicochemical properties of dual fortified yogurt with extruded flaxseed omega fatty acids and fibers for hypercholesterolemic subjects

2019 ◽  
Vol 8 (1) ◽  
pp. 273-280
Author(s):  
Nazir Ahmad ◽  
Muhammad Faisal Manzoor ◽  
Umair Shabbir ◽  
Saeed Ahmed ◽  
Tariq Ismail ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Physicochemical Properties ◽  
Omega Fatty Acids ◽  
Hypercholesterolemic Subjects

scholarly journals Tart Cherry Extract and Omega Fatty Acids Reduce Behavioral Deficits, Gliosis, and Amyloid-Beta Deposition in the 5xFAD Mouse Model of Alzheimer’s Disease

2021 ◽  
Vol 11 (11) ◽  
pp. 1423
Author(s):  
Zackary Bowers ◽  
Panchanan Maiti ◽  
Ali Bourcier ◽  
Jarod Morse ◽  
Kenneth Jenrow ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fatty Acids ◽  
Mouse Model ◽  
Neuronal Morphology ◽  
Omega Fatty Acids ◽  
Tart Cherry ◽  
Therapeutic Benefits ◽  
Model Of Alzheimer’S Disease ◽  
5Xfad Mice

Combined treatments using polyphenols and omega fatty acids provide several therapeutic benefits for a variety of age-related disorders, including Alzheimer’s disease (AD). Previously, we found a commercial product, Total Body Rhythm (TBR), consisting of tart cherry extract, a potent polyphenol, and omega fatty acids, significantly reduced memory, and neuropathological deficits in the 192 IgG-saporin mouse model of AD. The present study assessed the efficacy of TBR for treating behavioral and neuropathological deficits in the 5xFAD model of AD. Both 6- and 12-month-old 5xFAD mice and age-matched wild-type controls received TBR (60 mg/kg) or the equivalent dose of vehicle (0.5% methylcellulose) via oral administration, every other day for two months. All mice were tested in the open field (OF), novel object recognition (NOR), and the Morris water maze (MWM) tasks. In addition, neuronal morphology, neurodegeneration, Aβ plaque load, and glial activation were assessed. TBR treatment reduced memory deficits in the MWM and NOR tests and lessened anxiety levels in the OF task, mostly in the 6-month-old male mice. TBR also protected against neuron loss, reduced activation of astrocytes and microglia, primarily in 6-month-old mice, and attenuated Aβ deposition. These results suggest that the combination of tart cherry extract and omega fatty acids in TBR can reduce AD-like deficits in 5xFAD mice.

scholarly journals Changes in the Contents of Dietary Fibers, Minerals, Free Amino Acids, and Fatty Acids during Processing of Dried Nori.

1994 ◽  
Vol 60 (1) ◽  
pp. 117-123 ◽  
Author(s):  
Yumiko Yoshie ◽  
Takeshi Suzuki ◽  
Takaaki Shirai ◽  
Toshiyuki Hirano
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Free Amino Acids ◽  
Free Amino ◽  
Dietary Fibers

scholarly journals Applying mass spectrometry-based assays to explore gut microbial metabolism and associations with disease

2020 ◽  
Vol 58 (5) ◽  
pp. 719-732 ◽  
Author(s):  
Liam M. Heaney
Keyword(s):  
Mass Spectrometry ◽  
Amino Acids ◽  
Fatty Acids ◽  
Short Chain Fatty Acids ◽  
Dietary Fibers ◽  
Clinical Tool ◽  
Health And Disease ◽  
Research Populations ◽  
The Impact ◽  
By Products

AbstractThe workings of the gut microbiome have gained increasing interest in recent years through the mounting evidence that the microbiota plays an influential role in human health and disease. A principal focus of this research seeks to further understand the production of metabolic by-products produced by bacteria resident in the gut, and the subsequent interaction of these metabolites on host physiology and pathophysiology of disease. Gut bacterial metabolites of interest are predominately formed via metabolic breakdown of dietary compounds including choline and ʟ-carnitine (trimethylamine N-oxide), amino acids (phenol- and indole-containing uremic toxins) and non-digestible dietary fibers (short-chain fatty acids). Investigations have been accelerated through the application of mass spectrometry (MS)-based assays to quantitatively assess the concentration of these metabolites in laboratory- and animal-based experiments, as well as for direct circulating measurements in clinical research populations. This review seeks to explore the impact of these metabolites on disease, as well as to introduce the application of MS for those less accustomed to its use as a clinical tool, highlighting pertinent research related to its use for measurements of gut bacteria-mediated metabolites to further understand their associations with disease.

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