scholarly journals Changes of renal histopathology and the role of Nrf2/HO-1 in asphyxial cardiac arrest model in rats

2021 ◽  
Vol 36 (6) ◽  
Author(s):  
Ali Jawad ◽  
Yeo-Jin Yoo ◽  
Jae Chol Yoon ◽  
Weishun Tian ◽  
Md Sadikul Islam ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Renal Histopathology ◽  
Asphyxial Cardiac Arrest

Disadvantages of Overcorrecting Acidemia in Cardiopulmonary Resuscitation

1985 ◽  
Vol 1 (3) ◽  
pp. 229-236
Author(s):  
G.H. Meuret ◽  
M. Mussler
Keyword(s):  
Cardiac Arrest ◽  
Cardiopulmonary Resuscitation ◽  
Life Support ◽  
Advanced Life Support ◽  
Preceding Paper ◽  
Convincing Evidence ◽  
Phase Iii ◽  
Optimal Sequence ◽  
Asphyxial Cardiac Arrest

Rapid and repeated administration of concentrated NaHCO3 solutions during cardiopulmonary resuscitation (CPR) has become routine since the advent of modern resuscitation techniques (1), although it has been pointed out since the early 1960s that acidemia results from prolonged arrest time and that brief arrests may not require NaHCO3 administration (6,8,13). In spite of the widespread use of large amounts of NaHCO3 there is no convincing evidence that the routine use of this drug offers a clear benefit. Only a few studies have been undertaken to ascertain the role of acidosis and acidemia in survival from cardiac arrest, and the possibility of overcorrecting with NaHCO3 in CPR cases (3,4,8,11). Therefore, the intention of this study was: 1) to clarify the role of acidemia in CPR; 2) to investigate the effects of overcorrection of acidemia (leading to metabolic alkalemia; 3) to test the accurate doses of NaHCO3; 4) to examine the optimal sequence of drug administration in CPR, i.e., whether NaHCO3 or epinephrine should be administered as the first drug.During attempts at restoring spontaneous circulation (CPCR Phase II, advanced life support) (12), and during post-CPR prolonged life support (CPCR Phase III) (12), measurements were made in dogs following resuscitation from asphyxial cardiac arrest. The model and methods used have been described in the preceding paper of this Journal. Asphyxial cardiac arrest (mechanical asystole, electromechanical dissociation) was reversed with open-chest CPR and defibrillation as necessary to 20 min max.

Neuroprotective effects of dexmedetomidine-hypothermia after asphyxial cardiac arrest in rats

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S27-S27
Author(s):  
Tetsu Kimura ◽  
Toru Goyagi ◽  
Makoto Tanaka ◽  
Yoshitsugu Tobe ◽  
Yoko Masaki ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Neuroprotective Effects ◽  
Asphyxial Cardiac Arrest

699 Cardiac Arrest After Cardiac Surgery : Role of Simulation for the Intensive Care Team Performance

2012 ◽  
Vol 28 (5) ◽  
pp. S366 ◽  
Author(s):  
Y. Lamarche ◽  
M. Pagé ◽  
M. Laflamme ◽  
I. El-Hamamsy ◽  
D. Bouchard ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Cardiac Surgery ◽  
Intensive Care ◽  
Team Performance ◽  
Care Team
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