scholarly journals Assessment of the frailty level of elderly people with chronic kidney disease undergoing hemodialysis

2014 ◽  
Vol 27 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Fabiana de Souza Orlandi ◽  
Gabriela Dutra Gesualdo

OBJECTIVE: To assess the frailty level of elderly people with chronic kidney disease undergoing hemodialysis.METHODS: This is a cross-sectional study involving 60 participants and carried out at a Renal Replacement Therapy Unit. The Edmonton Frail Scale, translated and validated to Portuguese, was used as the instrument of research.RESULTS: Around 35.0% of the elderly showed no frailty, 26.7% were vulnerable, 20.0% showed mild frailty, 13.3% moderate frailty and 5.0% severe frailty.CONCLUSION: The frailty level of elderly people with chronic kidney disease undergoing hemodialysis was high and the number of elderly people who are vulnerable to frailty was also high.

2021 ◽  
Vol 11 (34) ◽  
pp. 142-151
Author(s):  
Isabel Pires Barra ◽  
Marina De Góes Salvetti ◽  
Viviane Peixoto dos Santos Pennafort ◽  
Francisca Íris Araújo de Brito ◽  
Maria Júlia Guimarães Oliveira Soares ◽  
...  

Identificar a ocorrência de fadiga em idosos com doença renal crônica em hemodiálise. Estudo descritivo, transversal e abordagem quantitativa, realizado de setembro a novembro de 2018 por meio da Escala de Fadiga de Piper-revisada. Participaram do estudo 45 idosos com idades entre 60 a 86 anos, 62,2% eram do sexo masculino. Identificou-se fadiga em 97,7% dos idosos e as causas atribuídas com maior frequência foram às sessões de hemodiálise (37,8%) e estresse (13,3%). Quanto aos fatores que promoveram alívio de fadiga, foram descritos descansar (53,3%), dormir (6,7%) e se alimentar (6,7%). A fadiga mostrou-se um achado relevante entre os idosos pesquisados, por isso merece a atenção da equipe de enfermagem para identificação e adequado manejo.Descritores: Diálise Renal, Idoso, Fadiga. Fatigue in elderly submitted to hemodialysis treatmentAbstract: To identify the occurrence of fatigue in the elderly with chronic kidney disease undergoing hemodialysis. A descriptive, cross-sectional study with a quantitative approach, carried out from September to November 2018 using the revised Piper Fatigue Scale. 45 elderly people aged 60 to 86 years participated on the study, 62.2% were male. Fatigue was identified in 97.7% of the elderly and the most frequently attributed causes were hemodialysis (37.8%) and stress (13.3%). As for the factors that promoted fatigue relief, rest (53.3%), sleep (6.7%) and eating (6.7%) were described. Fatigue proved to be a relevant finding among the elderly surveyed, which is why it deserves the attention of the nursing team for identification and adequate management.Descritores: Renal Dialysis, Age, Fatigue. Fatiga en personas mayores presentadas al tratamiento de hemodiálisisResumen: Identificar la aparición de fatiga en ancianos con enfermedad renal crónica en hemodiálisis. Un estudio descriptivo, transversal con un enfoque cuantitativo, llevado a cabo de septiembre a noviembre de 2018 utilizando la Escala de Fatiga Piper revisada. 45 personas mayores de 60 a 86 años participaron en el estudio, 62.2% eran hombres. La fatiga se identificó en el 97.7% de los ancianos y las causas más frecuentemente atribuidas fueron la hemodiálisis (37.8%) y el estrés (13.3%). En cuanto a los factores que promovieron el alivio de la fatiga, se describió el descanso (53.3%), el sueño (6.7%) y la alimentación (6.7%). La fatiga resultó ser un hallazgo relevante entre los ancianos encuestados, por lo que merece la atención del equipo de enfermería para su identificación y manejo adecuado.Descriptores: Diálisis Renal, Anciano, Fatiga.


Biomedicines ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 19
Author(s):  
Ashani Lecamwasam ◽  
Tiffanie M. Nelson ◽  
Leni Rivera ◽  
Elif I. Ekinci ◽  
Richard Saffery ◽  
...  

(1) Background: Individuals with diabetes and chronic kidney disease display gut dysbiosis when compared to healthy controls. However, it is unknown whether there is a change in dysbiosis across the stages of diabetic chronic kidney disease. We investigated a cross-sectional study of patients with early and late diabetes associated chronic kidney disease to identify possible microbial differences between these two groups and across each of the stages of diabetic chronic kidney disease. (2) Methods: This cross-sectional study recruited 95 adults. DNA extracted from collected stool samples were used for 16S rRNA sequencing to identify the bacterial community in the gut. (3) Results: The phylum Firmicutes was the most abundant and its mean relative abundance was similar in the early and late chronic kidney disease group, 45.99 ± 0.58% and 49.39 ± 0.55%, respectively. The mean relative abundance for family Bacteroidaceae, was also similar in the early and late group, 29.15 ± 2.02% and 29.16 ± 1.70%, respectively. The lower abundance of Prevotellaceae remained similar across both the early 3.87 ± 1.66% and late 3.36 ± 0.98% diabetic chronic kidney disease groups. (4) Conclusions: The data arising from our cohort of individuals with diabetes associated chronic kidney disease show a predominance of phyla Firmicutes and Bacteroidetes. The families Ruminococcaceae and Bacteroidaceae represent the highest abundance, while the beneficial Prevotellaceae family were reduced in abundance. The most interesting observation is that the relative abundance of these gut microbes does not change across the early and late stages of diabetic chronic kidney disease, suggesting that this is an early event in the development of diabetes associated chronic kidney disease. We hypothesise that the dysbiotic microbiome acquired during the early stages of diabetic chronic kidney disease remains relatively stable and is only one of many risk factors that influence progressive kidney dysfunction.


Medicina ◽  
2020 ◽  
Vol 57 (1) ◽  
pp. 15
Author(s):  
Altynay Balmukhanova ◽  
Kairat Kabulbayev ◽  
Harika Alpay ◽  
Assiya Kanatbayeva ◽  
Aigul Balmukhanova

Background and objectives: Chronic kidney disease (CKD) in children is a complex medical and social issue around the world. One of the serious complications is mineral-bone disorder (CKD-MBD) which might determine the prognosis of patients and their quality of life. Fibroblast growth factor 23 (FGF-23) is a phosphaturic hormone which is involved in the pathogenesis of CKD-MBD. The purpose of the study was to determine what comes first in children with CKD: FGF-23 or phosphate. Materials and Methods: This cross-sectional study included 73 children aged 2–18 years with CKD stages 1–5. We measured FGF-23 and other bone markers in blood samples and studied their associations. Results: Early elevations of FGF-23 were identified in children with CKD stage 2 compared with stage 1 (1.6 (1.5–1.8) pmol/L versus 0.65 (0.22–1.08), p = 0.029). There were significant differences between the advanced stages of the disease. FGF-23 correlated with PTH (r = 0.807, p = 0.000) and phosphate (r = 0.473, p = 0.000). Our study revealed that the elevated level of FGF-23 went ahead hyperphosphatemia and elevated PTH. Thus, more than 50% of children with CKD stage 2 had the elevating level of serum FGF-23, and that index became increasing with the disease progression and it achieved 100% at the dialysis stage. The serum phosphate increased more slowly and only 70.6% of children with CKD stage 5 had the increased values. The PTH increase was more dynamic. Conclusions: FGF-23 is an essential biomarker, elevates long before other markers of bone metabolism (phosphate), and might represent a clinical course of disease.


2021 ◽  
Author(s):  
Farzam Tajalli ◽  
Seyed‐Mohamad‐Sadegh Mirahmadi ◽  
Samaneh Mozafarpoor ◽  
Azadeh Goodarzi ◽  
Mitra Nasiri Partovi ◽  
...  

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