scholarly journals Diagnosis and management of Paget?s disease of bone

2014 ◽  
Vol 58 (6) ◽  
pp. 587-599 ◽  
Author(s):  
Luiz Griz ◽  
Daniele Fontan ◽  
Patricia Mesquita ◽  
Marise Lazaretti-Castro ◽  
Victoria Zeghbi Cochenski Borba ◽  
...  

Objective: To conduct a literature review on the diagnosis and management of Paget’s disease of bone. Materials and methods: This scientific statement was generated by a request from the Brazilian Medical Association (AMB) to the Brazilian Society of Endocrinology and Metabolism (SBEM) as part of its Clinical Practice Guidelines program. Articles were identified by searching in PubMed and Cochrane databases as well as abstracts presented at the Endocrine Society, Brazilian Society for Endocrinology Annual Meetings and the American Society for Bone and Mineral Research Annual Meeting during the last 5 years. Grading quality of evidence and strength of recommendation were adapted from the first report of the Oxford Centre for Evidence-based Medicine. All grades of recommendation, including “D”, are based on scientific evidence. The differences between A, B, C and D, are due exclusively to the methods employed in generating evidence. Conclusion: We present a scientific statement on Paget’s disease of bone providing the level of evidence and the degree of recommendation regarding causes, clinical presentation as well as surgical and medical treatment. Arq Bras Endocrinol Metab. 2014;58(6):587-99

2013 ◽  
Vol 57 (6) ◽  
pp. 406-424 ◽  
Author(s):  
Francisco Bandeira ◽  
Luiz Griz ◽  
Narriane Chaves ◽  
Nara Crispim Carvalho ◽  
Lívia Maria Borges ◽  
...  

OBJECTIVE: To conduct a literature review on the diagnosis and management of primary hyperparathyroidism including the classical hipercalcemic form as well as the normocalcemic variant. MATERIALS AND METHODS: This scientific statement was generated by a request from the Brazilian Medical Association (AMB) to the Brazilian Society for Endocrinology as part of its Clinical Practice Guidelines program. Articles were identified by searching in PubMed and Cochrane databases as well as abstracts presented at the Endocrine Society, Brazilian Society for Endocrinology Annual Meetings and the American Society for Bone and Mineral Research Annual Meeting during the last 5 years. Grading quality of evidence and strength of recommendation were adapted from the first report of the Oxford Centre for Evidence-based Medicine. All grades of recommendation, including "D", are based on scientific evidence. The differences between A, B, C and D, are due exclusively to the methods employed in generating evidence. CONCLUSION: We present a scientific statement on primary hyperparathyroidism providing the level of evidence and the degree of recommendation regarding causes, clinical presentation as well as surgical and medical treatment.


2019 ◽  
Vol 34 (4) ◽  
pp. e3657 ◽  
Author(s):  
Stuart H Ralston ◽  
Luis Corral-Gudino ◽  
Cyrus Cooper ◽  
Roger M Francis ◽  
William D Fraser ◽  
...  

2001 ◽  
Vol 16 (8) ◽  
pp. 1379-1387 ◽  
Author(s):  
Kenneth W. Lyles ◽  
Ethel S. Siris ◽  
Frederick R. Singer ◽  
Pierre J. Meunier

2019 ◽  
Vol 27 (1) ◽  
pp. 31-32
Author(s):  
Felipe Augusto Kazan de Oliveira ◽  
Fábio Fernando Eloi Pinto ◽  
Trajano Sardenberg ◽  
Gilberto José Cação Pereira ◽  
Emílio Carlos Curcelli ◽  
...  

ABSTRACT Paget's disease of bone is a chronic condition characterized by focal abnormalities of absorption and formation of bone, and it may lead to anatomical deformities, pain, fractures, and malignant transformation. It is common in the UK, Australia, New Zealand, and North America and has a strong hereditary component, affecting first- to third-degree relatives. The etiology remains unclear and treatment is based on control of the disease with bisphosphonates, with the aim of relieving symptoms and correcting laboratory abnormalities. Surgical treatment may also be necessary to correct deformities or treat pathological fractures. This study evaluated the management and course of 8 patients with Paget's disease of bone, followed in the Orthopedic Clinic of this hospital. Among these patients, 1 had concomitant advanced prostate carcinoma, highlighting the association between Paget's disease and secondary bone diseases that can affect the differential diagnosis. Level of evidence IV, Study type: Case Series.


2014 ◽  
Vol 99 (12) ◽  
pp. 4408-4422 ◽  
Author(s):  
Frederick R. Singer ◽  
Henry G. Bone ◽  
David J. Hosking ◽  
Kenneth W. Lyles ◽  
Mohammad Hassan Murad ◽  
...  

BMJ ◽  
1996 ◽  
Vol 312 (7029) ◽  
pp. 491-494 ◽  
Author(s):  
D. Hosking ◽  
P. J Meunier ◽  
J. D Ringe ◽  
J.-Y. Reginster ◽  
C. Gennari

2006 ◽  
Vol 24 (5) ◽  
pp. 359-367 ◽  
Author(s):  
Shinjiro Takata ◽  
Jun Hashimoto ◽  
Kiyoshi Nakatsuka ◽  
Noriko Yoshimura ◽  
Kousei Yoh ◽  
...  

2006 ◽  
Vol 39 (11) ◽  
pp. 20
Author(s):  
Elizabeth Mechcatie ◽  
Lora T. McGlade

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