scholarly journals Effects of Knee Internal Rotation Exercises on Knee Adduction Moment and Function of Elderly Women with Knee Osteoarthritis: A Randomized Controlled Trial

2015 ◽  
Vol 30 (3) ◽  
pp. 339-344 ◽  
Author(s):  
Futoshi IKUTA ◽  
Hiroki DEGUCHI ◽  
Koichi OKAMOTO ◽  
Koji NAGOYA ◽  
Fumiya SATO ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Knee Osteoarthritis ◽  
Internal Rotation ◽  
Elderly Women ◽  
Controlled Trial ◽  
Knee Adduction Moment ◽  
Randomized Controlled ◽  
And Function

Long-term use of minimal footwear on pain, self-reported function, analgesic intake, and joint loading in elderly women with knee osteoarthritis: A randomized controlled trial

2015 ◽  
Vol 30 (10) ◽  
pp. 1194-1201 ◽  
Author(s):  
Francis Trombini-Souza ◽  
Alessandra B. Matias ◽  
Mariane Yokota ◽  
Marco K. Butugan ◽  
Claudia Goldenstein-Schainberg ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Knee Osteoarthritis ◽  
Elderly Women ◽  
Controlled Trial ◽  
Joint Loading ◽  
Randomized Controlled

scholarly journals Effectiveness And Safety of Acupotomy For Knee Osteoarthritis: Study Protocol For A Randomized Controlled Trial

2021 ◽  
Author(s):  
Wu-Zhong Cheng ◽  
Tian-Li Li ◽  
Ren Guo ◽  
Ping Chen ◽  
Wei-Shuai Du ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Knee Osteoarthritis ◽  
Controlled Trial ◽  
Joint Fluid ◽  
Clinical Trial Registry ◽  
Randomized Controlled ◽  
Group A ◽  
And Function ◽  
Group D ◽  
Topical Diclofenac

Abstract Background: Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders. Acupotomy may be effective for KOA, but evidence is limited. The aim of this trial is to determine the effectiveness and safety of acupotomy for KOA.Methods/design: This is a parallel-group, assessor-blinded randomized controlled trial. Two hundred patients with KOA will be recruited and randomly assigned to two groups (group A or group D) in a 1:1 ratio. Patients in group A will receive acupotomy and topical diclofenac diethylamine for 4 weeks, while patients in group D will receive topical diclofenac diethylamine alone for 4 weeks. The primary outcome will be the response rate—the proportion of patients who achieve the minimal clinically important improvement in pain and function at week 4 compared with baseline. Secondary outcomes will include pain, function, quality of life, the use of rescue medicine (loxoprofen sodium) and adverse events at weeks 4, 8 and 24 after randomization. Besides, joint fluid and serum will be collected to assess the level of inflammatory cytokines, like TNF-α, IL-1β and MMP-3.Discussion: This study will contribute to a better understanding of the effectiveness and safety of acupotomy in combination with topical nonsteroidal anti-inflammatory drugs. Results of the study will be of great importance for the guidelines of clinical therapy.Trial registration: Chinese Clinical Trial Registry (No. ChiCTR2100043005, http://www.chictr.org.cn/showproj.aspx?proj=121348) Registered on 4 February 2021.

scholarly journals Effectiveness and safety of acupotomy for knee osteoarthritis: study protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shu-Ming Li ◽  
Tian-Li Li ◽  
Ren Guo ◽  
Ping Chen ◽  
Wei-Shuai Du ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Knee Osteoarthritis ◽  
Controlled Trial ◽  
Joint Fluid ◽  
Clinical Trial Registry ◽  
Randomized Controlled ◽  
Group A ◽  
And Function ◽  
Group D ◽  
Topical Diclofenac

Abstract Background Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders. Acupotomy may be effective for KOA, but the evidence is limited. This trial aims to determine the effectiveness and safety of acupotomy for KOA. Methods/design This is a parallel-group, assessor-blinded randomized controlled trial. Two hundred patients with KOA will be recruited and randomly assigned to two groups (group A or group D) in a 1:1 ratio. Patients in group A will receive acupotomy and topical diclofenac diethylamine for 4 weeks, while patients in group D will receive topical diclofenac diethylamine alone for 4 weeks. The primary outcome will be the response rate—the proportion of patients who achieve the minimal clinically important improvement in pain and function at week 4 compared with baseline. Secondary outcomes will include pain, function, quality of life, the use of rescue medicine (loxoprofen sodium), and adverse events at weeks 4, 8, and 24 after randomization. Besides, joint fluid and serum will be collected to assess the level of inflammatory cytokines, like TNF-α, IL-1β, and MMP-3. Discussion This study will contribute to a better understanding of the effectiveness and safety of acupotomy in combination with topical nonsteroidal anti-inflammatory drugs. If the hypothesis is confirmed, acupotomy may be recommended as adjunctive therapy for patients with KOA. Results of the study will be of great importance for the guidelines of clinical therapy. Trial registration Chinese Clinical Trial Registry ChiCTR2100043005 Registered on 4 February 2021.

A Meta-Analysis of Knee Orthosis Uptake in Reducing Pain in Patients with Knee Osteoarthritis

2020 ◽  
Author(s):  
Atika Febri Anggriani ◽  
◽  
Agus Kristiyanto ◽  
Setyo Sri Rahardjo ◽  
◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Knee Osteoarthritis ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Knee Adduction Moment ◽  
Valgus Knee ◽  
Randomized Controlled ◽  
Central Java ◽  
Keywords Osteoarthritis ◽  
Knee Orthosis

ABSTRACT Background: Osteoarthritis (OA) of knee joint is a degenerative disease that results in decreased function and pain. Orthotic devices can reduce knee adduction moment, pain, and improve function in knee OA. The purpose of this study was to examine knee orthosis uptake in reducing pain in patients with knee osteoarthritis. Subjects and Method: A meta-analysis and systematic review was conducted by search published articles from PubMed, Science Direct, Google Sscholar, Mendeley, and Clinical key databases. Keywords used “knee orthosis” OR “KO” AND “valgus knee brace” AND “brace” AND “knee support” AND “valgus knee support” AND “osteoarthritis” AND “patellofemoral osteoarthritis” AND “knee pain” AND “effect knee orthosis for osteoarthritis” AND “randomized controlled trial”. The inclusion criteria were full text and using randomized controlled trial study design. The articles were selected by PRISMA flow chart and the quantitative data were analyzed by Revman 5.3. Results: 6 studies reported that knee orthosis uptake reduces pain in patients with knee osteoarthritis (Mean Difference= -0.53; 95% CI= -1.39 to 0.33; p= 0.230) with heterogeneity I2= 95%. Conclusion: Knee orthosis uptake reduces pain in patients with knee osteoarthritis. Keywords: osteoarthritis, pain, knee orthosis, knee valgus brace Correspondence: Atika Febri Anggriani. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085728794960. DOI: https://doi.org/10.26911/the7thicph.05.44

Exercise on balance and function for knee osteoarthritis: A randomized controlled trial

2018 ◽  
Vol 22 (1) ◽  
pp. 76-82 ◽  
Author(s):  
Roberta de Matos Brunelli Braghin ◽  
Elisa Cavalheiro Libardi ◽  
Carina Junqueira ◽  
Marcello Henrique Nogueira – Barbosa ◽  
Daniela Cristina Carvalho de Abreu
Keyword(s):  
Randomized Controlled Trial ◽  
Knee Osteoarthritis ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
And Function
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