scholarly journals Pulmonary Oxidative Stress is not Increased by Short-period High Intensity Exercise in Healthy Young Subjects

2011 ◽  
Vol 26 (2) ◽  
pp. 287-290 ◽  
Author(s):  
Sayaka DOMEN ◽  
Shunsuke TAITO ◽  
Kana KONISHI ◽  
Makoto TAKAHASHI ◽  
Kiyokazu SEKIKAWA ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Short Period ◽  
Young Subjects

Effects of high-amount–high-intensity exercise on in vivo platelet activation: Modulation by lipid peroxidation and AGE/RAGE axis

2013 ◽  
Vol 110 (12) ◽  
pp. 1232-1240 ◽  
Author(s):  
Francesca Santilli ◽  
Natale Vazzana ◽  
Pierpaolo Iodice ◽  
Stefano Lattanzio ◽  
Rossella Liani ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Exercise Training ◽  
Platelet Activation ◽  
High Intensity ◽  
Plasma Levels ◽  
High Intensity Exercise ◽  
Similar Amount ◽  
Activation Markers

SummaryPhysical activity is associated with cardiovascular risk reduction, but the effects of exercise on platelet activation remain controversial. We investigated the effects of regular high-amount, high intensity aerobic exercise on in vivo thromboxane (TX)-dependent platelet activation and plasma levels of platelet-derived proteins, CD40L and P-selectin, and whether platelet variables changes may be related to changes in high-density lipoprotein (HDL) and in the extent of oxidative stress and oxidative stress-related inflammation, as reflected by urinary isoprostane excretion and endogenous soluble receptor for advanced glycation end-products (esRAGE), respectively. Urinary excretion of 11-dehydro-TXB2 and 8-iso-prostaglandin (PG)F2α and plasma levels of P-selectin, CD40L and esRAGE were measured before and after a eight-week standardised aerobic high-amount–high-intensity training program in 22 sedentary subjects with low-to-intermediate risk. Exercise training had a clear beneficial effect on HDL cholesterol (+10%, p=0.027) and triglyceride (-27%, p=0.008) concentration. In addition, a significant (p<0.0001) decrease in urinary 11-dehydro-TXB2 (26%), 8-iso-PGF2α (21 %), plasma P-selectin (27%), CD40L (35%) and a 61% increase in esRAGE were observed. Multiple regression analysis revealed that urinary 8-iso-PGF2α [beta=0.33, SEM=0.116, p=0.027] and esRAGE (beta=-0.30, SEM=31.3, p=0.046) were the only significant predictors of urinary 11-dehydro-TXB2 excretion rate over the training period. In conclusion, regular high-amount–high-intensity exercise training has broad beneficial effects on platelet activation markers, paralleled and possibly associated with changes in the lipoprotein profile and in markers of lipid peroxidation and AGE/RAGE axis. Our findings may help explaining why a similar amount of exercise exerts significant benefits in preventing cardiovascular events.

High-intensity Exercise Modifies the Effects of Stanozolol on Brain Oxidative Stress in Rats

2015 ◽  
Vol 36 (12) ◽  
pp. 984-991 ◽  
Author(s):  
D. Camiletti-Moirón ◽  
V. Aparicio ◽  
E. Nebot ◽  
G. Medina ◽  
R. Martínez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Brain Oxidative Stress

Pre-exercise low-level laser therapy improves performance and levels of oxidative stress markers in mdx mice subjected to muscle fatigue by high-intensity exercise

2015 ◽  
Vol 30 (6) ◽  
pp. 1719-1727 ◽  
Author(s):  
Andreia Aparecida de Oliveira Silva ◽  
Ernesto Cesar Pinto Leal-Junior ◽  
Katia de Angelis Lobo D’Avila ◽  
Andrey Jorge Serra ◽  
Regiane Albertini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Muscle Fatigue ◽  
Laser Therapy ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Low Level Laser Therapy ◽  
Mdx Mice ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Level Laser

scholarly journals Collective occurrence of rhabdomyolysis after high-intensity resistance training--- A prospective study

2020 ◽  
Author(s):  
Haitao Tu ◽  
Xiaoqing Cai ◽  
Liangliang Wang ◽  
Xingbo Wu ◽  
Liangyou Zhang ◽  
...  
Keyword(s):  
High Intensity ◽  
Military Training ◽  
Signs And Symptoms ◽  
Serum Lactate ◽  
High Intensity Exercise ◽  
Electrolyte Imbalance ◽  
Serum Lactate Dehydrogenase ◽  
Sample Mean ◽  
Short Period ◽  
Average Serum

Abstract Background: Rhabdomyolysis is a syndrome characterized by muscle necrosis and release of intracellular muscle components into systemic circulation. Common causes include high-intensity exercise, crush injury, high fever, drugs, and inflammation. Here, we have a prospective observational study of collective rhabdomyolysis caused by infrequent short-term high-intensity exercise. Methods: The patients were a group of adolescents, of which 35 developed severe muscle pain and dark-brown urine after military training and were hospitalized, while others developed mild symptoms and returned to school after relief of symptoms following outpatient treatment. We used SPSS 13.0 to calculate the sample mean and standard deviation of various laboratory indicators. Results: The average serum creatinine kinase was 33532.43±39982.95 U/L, and average serum lactate dehydrogenase was 1816.97±1413.59 U/L at the time of admission. When they were discharged, the above two indicators became 1902.2±1366.37 U/L and 210.31±61.27 U/L. Signs and symptoms improved in all patients after the intravenous injection of average 5000ml within 5.5 days of normal saline and balance solution and implementation of a bed rest regimen. No complications occurred (e.g., acute renal failure, disseminated intravascular coagulation, or electrolyte imbalance). All patients were relieved of symptoms and discharged after an average of 5.47 days of hospitalization. Of these, 20 patients were prescribed medical treatment and returned to the clinic within 1 month after discharge. Conclusions: Suddenly and dramatically increase the amount of exercises in a short period of time is easy to cause rhabdomyolysis. We hope that everyone can avoid similar situations.

scholarly journals Exercise-Induced Muscle Damage and Running Economy in Humans

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Cláudio de Oliveira Assumpção ◽  
Leonardo Coelho Rabello Lima ◽  
Felipe Bruno Dias Oliveira ◽  
Camila Coelho Greco ◽  
Benedito Sérgio Denadai
Keyword(s):  
Muscle Damage ◽  
High Intensity ◽  
Energy Demand ◽  
Negative Impact ◽  
High Intensity Exercise ◽  
Running Economy ◽  
Running Performance ◽  
Downhill Running ◽  
Short Period ◽  
Exercise Induced

Running economy (RE), defined as the energy demand for a given velocity of submaximal running, has been identified as a critical factor of overall distance running performance. Plyometric and resistance trainings, performed during a relatively short period of time (~15–30 days), have been successfully used to improve RE in trained athletes. However, these exercise types, particularly when they are unaccustomed activities for the individuals, may cause delayed onset muscle soreness, swelling, and reduced muscle strength. Some studies have demonstrated that exercise-induced muscle damage has a negative impact on endurance running performance. Specifically, the muscular damage induced by an acute bout of downhill running has been shown to reduce RE during subsequent moderate and high-intensity exercise (>65% VO2max). However, strength exercise (i.e., jumps, isoinertial and isokinetic eccentric exercises) seems to impair RE only for subsequent high-intensity exercise (~90% VO2max). Finally, a single session of resistance exercise or downhill running (i.e., repeated bout effect) attenuates changes in indirect markers of muscle damage and blunts changes in RE.

scholarly journals The effects of a novel high intensity exercise intervention on established markers of cardiovascular disease and health in Scottish adolescent youth

2012 ◽  
Vol 1 (2) ◽  
pp. 24 ◽  
Author(s):  
Duncan S. Buchan ◽  
John D. Young ◽  
Alan D. Simpson ◽  
Non E. Thomas ◽  
Stephen-Mark Cooper ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Physical Fitness ◽  
Cardiorespiratory Fitness ◽  
High Intensity ◽  
Exercise Intervention ◽  
High Intensity Exercise ◽  
Control Group ◽  
Cvd Risk ◽  
Exercise Interventions ◽  
Short Period

This study examined the effects of high intensity exercise on physical fitness components and cardiovascular disease (CVD) risk factors in youth. Forty-one participants (15-17 years) were divided into a control and an intervention (high intensity exercise, HIT) group. The HIT group (15 boys, 2 girls) performed three weekly sessions over seven weeks consisting of either four to six repeats of maximal sprint running with 20-30 s recovery. The control group (20 boys, 4 girls) continued their normal activity patterns. All participants had indices of obesity and blood pressure (BP) recorded in addition to four physical performance measures pre-and post-intervention: cardiorespiratory fitness, muscular power, sprint speed and agility. In the HIT group, significant improvements in cardiorespiratory fitness (P&lt;0.01) and agility (P&lt;0.05) were noted. Participants in the control group, meanwhile, experienced a significant decrease in counter movement jump performance. These findings demonstrate that brief, intense exercise interventions are useful for improving indices of physical fitness in a short period of time.

Effective Nutritional Ergogenic Aids

1999 ◽  
Vol 9 (2) ◽  
pp. 229-239 ◽  
Author(s):  
Elizabeth Applegate
Keyword(s):  
Oxidative Stress ◽  
High Intensity ◽  
Ergogenic Aids ◽  
Cellular Component ◽  
High Intensity Exercise ◽  
Amino Acid Supplementation ◽  
Intense Exercise ◽  
Short Term ◽  
Glycogen Stores ◽  
High Effort

Athletes use a variety of nutritional ergogenic aids to enhance performance. Most nutritional aids can be categorized as a potential energy source, an anabolic enhancer, a cellular component, or a recovery aid. Studies have consistently shown that carbohydrates consumed immediately before or after exercise enhance performance by increasing glycogen stores and delaying fatigue. Protein and amino acid supplementation may serve an anabolic role by optimizing body composition crucial in strength-related sports. Dietary antioxidants, such as vitamins C and E and carotenes, may prevent oxidative stress that occurs with intense exercise. Performance during high-intensity exercise, such as sprinting, may be improved with short-term creatine loading, and high-effort exercise lasting 1-7 min may be improved through bicarbonate loading immediately prior to activity. Caffeine dosing before exercise delays fatigue and may enhance performance of high-intensity exercise.

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