SV40 virus-like particles as an effective delivery system and its application to a vaccine carrier

2013 ◽  
Vol 12 (2) ◽  
pp. 199-210 ◽  
Author(s):  
Masaaki Kawano ◽  
Masanori Matsui ◽  
Hiroshi Handa
Keyword(s):  
Delivery System ◽  
Sv40 Virus ◽  
Virus Like Particles ◽  
Effective Delivery ◽  
Vaccine Carrier

scholarly journals Salmonella vaccine carrier strains: effective delivery system to trigger anti-tumor immunity by oral route

1999 ◽  
Vol 29 (2) ◽  
pp. 693-699 ◽  
Author(s):  
Eva Medina ◽  
Carlos A. Guzmán ◽  
Lothar H. Staendner ◽  
Mario P. Colombo ◽  
Paola Paglia
Keyword(s):  
Tumor Immunity ◽  
Delivery System ◽  
Oral Route ◽  
Effective Delivery ◽  
Vaccine Carrier

Development of a microRNA delivery system based on bacteriophage MS2 virus-like particles

FEBS Journal ◽  
2012 ◽  
Vol 279 (7) ◽  
pp. 1198-1208 ◽  
Author(s):  
Yang Pan ◽  
Yuan Zhang ◽  
Tingting Jia ◽  
Kuo Zhang ◽  
Jinming Li ◽  
...  
Keyword(s):  
Delivery System ◽  
Virus Like Particles ◽  
Bacteriophage Ms2 ◽  
Microrna Delivery

scholarly journals A Systematic Review on Drug Delivery Systems Based on Their Mechanism of Drug Release and Their Applications

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Amit Prakash ◽  
Amit Prakash
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Oral Drug Delivery ◽  
Cost Effective ◽  
Delivery Systems ◽  
Oral Drug ◽  
Effective Delivery ◽  
Route Of Delivery

Oral drug delivery is the most commonly used and preferred route of delivery of pharmaceuticals which has been successfully treating wide number of diseases. The advantages of this method of delivery are patient friendly, cost effective, established delivery system, noninvasiveness and convenient, and In the pharmaceutical field it is the most favored drug delivery system. Oral drug delivery systems along with other effective delivery system types that are effective and promising are discussed in this paper based on the mechanism of drug release.

MF59 Emulsion Is an Effective Delivery System for a Synthetic TLR4 Agonist (E6020)

2009 ◽  
Vol 26 (6) ◽  
pp. 1477-1485 ◽  
Author(s):  
Barbara C. Baudner ◽  
Vanessa Ronconi ◽  
Daniele Casini ◽  
Marco Tortoli ◽  
Jina Kazzaz ◽  
...  
Keyword(s):  
Delivery System ◽  
Tlr4 Agonist ◽  
Effective Delivery

Platelet microparticles: An effective delivery system for anti-viral drugs

2019 ◽  
Vol 51 ◽  
pp. 290-296 ◽  
Author(s):  
Sepehr Soleymani ◽  
Fatemeh Yari ◽  
Azam Bolhassani ◽  
Haleh Bakhshandeh
Keyword(s):  
Delivery System ◽  
Effective Delivery ◽  
Platelet Microparticles

scholarly journals Curcumin-Loaded Nanoparticles Based on Amphiphilic Hyaluronan-Conjugate Explored as Targeting Delivery System for Neurodegenerative Disorders

2020 ◽  
Vol 21 (22) ◽  
pp. 8846
Author(s):  
Giuseppe Pepe ◽  
Enrica Calce ◽  
Valentina Verdoliva ◽  
Michele Saviano ◽  
Vittorio Maglione ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Delivery System ◽  
Neurodegenerative Disorders ◽  
Natural Polysaccharide ◽  
Promising Therapeutic Approach ◽  
Targeting Delivery ◽  
Effective Delivery ◽  
Vitro Model

Identification of molecules able to promote neuroprotective mechanisms can represent a promising therapeutic approach to neurodegenerative disorders including Huntington’s disease. Curcumin is an antioxidant and neuroprotective agent, even though its efficacy is limited by its poor absorption, rapid metabolism, systemic elimination, and limited blood–brain barrier (BBB) permeability. Herein, we report on novel biodegradable curcumin-containing nanoparticles to favor the compound delivery and potentially enhance its brain bioavailability. The prepared hyaluronan-based materials able to self-assemble in stable spherical nanoparticles, consist of natural fatty acids chemically conjugated to the natural polysaccharide. The aim of this study is to provide a possible effective delivery system for curcumin with the expectation that, after having released the drug at the specific site, the biopolymer can degrade to nontoxic fragments before renal excretion, since all the starting materials are provided by natural resource. Our findings demonstrate that curcumin-encapsulated nanoparticles enter the cells and reduce their susceptibility to apoptosis in an in vitro model of Huntington’s disease.

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